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About

8 weeks ago she started having problems with her blood. Her red blood

cells, white blood cells, hemoglobin, and blood platelets are all very

low. They are declining at a rapid pace. Her Hemotalogist has no idea

why. He has checked her bone marrow, it shows that it is not working

right, but is inconclusive as to why. He is not sure if it's all the

meds she is taking.

Do you know what meds she is on. It is very possible that she may be developing medication induced leukemia. Sarc can get into the bone marrow, and if she is on some heavy duty immunosuppresants, they can deplete the white cells. This is something that we have to watch for, and most of the docs know at least to have CBC's and LFT's (complete blood counts and liver function tests) on a monthly basis. That way if something starts up, they can discontinue the immunosupressants and get the blood levels back up where they belong.

You might want to have her talk to her pharmacist and see if low blood counts are a side effect of the meds she's on.

Take care, and thank you for helping your aunt figure out this puzzle.

Sincerely,

Tracie

NS Co-owner/moderator************************************** AOL now offers free email to everyone. Find out more about what's free from AOL at http://www.aol.com.

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My Aunt was diagnosed with Neurosarcoidosis about 10 years ago. About

8 weeks ago she started having problems with her blood. Her red blood

cells, white blood cells, hemoglobin, and blood platelets are all very

low. They are declining at a rapid pace. Her Hemotalogist has no idea

why. He has checked her bone marrow, it shows that it is not working

right, but is inconclusive as to why. He is not sure if it's all the

meds she is taking.Or if it is another symptom of her progressing

disease. He is not familiar with Neurosarcoidosis. She has had 3 blood

transfusions in the last 6 weeks. The doctor is very concerned about

all of her numbers, but the low platelet is the biggest worry. Today

when she had her blood checked everything had gone down again despite

the treatments she has been given. Her platelet count is 9000, normal

is 150,000- 400,000, 10,000 or less is considered dangerous.

What I would like to know is there anyone who has had a similar

problem, and what did they do for treatment.

I would really appreciate any information.

Thanks,

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  • 2 weeks later...
Guest guest

>

> In a message dated 3/15/07 9:22:44 PM Pacific Standard Time,

> estellakeyes@... writes:

>

>

> > About

> > 8 weeks ago she started having problems with her blood. Her red blood

> > cells, white blood cells, hemoglobin, and blood platelets are all very

> > low. They are declining at a rapid pace. Her Hemotalogist has no idea

> > why. He has checked her bone marrow, it shows that it is not working

> > right, but is inconclusive as to why. He is not sure if it's all the

> > meds she is taking.

>

> Do you know what meds she is on. It is very possible that she may be

> developing medication induced leukemia. Sarc can get into the bone

marrow, and if

> she is on some heavy duty immunosuppresants, they can deplete the

white cells.

> This is something that we have to watch for, and most of the docs

know at

> least to have CBC's and LFT's (complete blood counts and liver

function tests) on

> a monthly basis. That way if something starts up, they can

discontinue the

> immunosupressants and get the blood levels back up where they belong.

> You might want to have her talk to her pharmacist and see if low

blood counts

> are a side effect of the meds she's on.

>

> Take care, and thank you for helping your aunt figure out this puzzle.

> Sincerely,

> Tracie

> NS Co-owner/moderator

>

>

> **************************************

Tracie,

Thank you for the information. Her Hemotalogist has diagnosed her with

Myelosdyplastic.She is on so many different meds, Neurontin,

Methadone, Prevacid, Valtrex,Zanaflex, just to name a few. They have

taken her off of Cytoxen and Prednisone. Two weeks ago she had five

treatments of a new chemo, Dacogen. But her levels continued to

decline, she has had 6 units of blood and 2 bags of platelets in three

weeks. She went in the hospital yesterday, more blood, the good news

is her platelets are back up to 23,000 and her hemoglobin is 11. Bad

news her white cells are 0.002 and she has an infection, they have her

on antibiotics. So we are hoping the white cells started going up also

and the infection gets cleared up. Doc is hopeful that the chemo is

working, I hope do she has to go for five more treatments next week.

We are just going day by day, it's all we can do! Thanks again for

listening to me.

>

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Estella, I'd get an opinion from a second hematologist. For cryin' out loud, this is his specialty & the guy has no clue? Like Tracie, I think it's wonderful that you are standing up for you aunt & advocating for her.

Ramblin' Rose

Moderator

Reply-To: Neurosarcoidosis To: Neurosarcoidosis Subject: Re: low blood plateletsDate: Wed, 28 Mar 2007 04:20:16 -0000

>> > > > > About> > 8 weeks ago she started having problems with her blood. Her red blood> > cells, white blood cells, hemoglobin, and blood platelets are all very> > low. They are declining at a rapid pace. Her Hemotalogist has no idea> > why. He has checked her bone marrow, it shows that it is not working> > right, but is inconclusive as to why. He is not sure if it's all the> > meds she is taking.> > Do you know what meds she is on. It is very possible that she may be > developing medication induced leukemia. Sarc can get into the bonemarrow, and if > she is on some heavy duty immunosuppresants, they can deplete thewhite cells. > This is something that we have to watch for, and most of the docsknow at > least to have CBC's and LFT's (complete blood counts and liverfunction tests) on > a monthly basis. That way if something starts up, they candiscontinue the > immunosupressants and get the blood levels back up where they belong.> You might want to have her talk to her pharmacist and see if lowblood counts > are a side effect of the meds she's on. > > Take care, and thank you for helping your aunt figure out this puzzle.> Sincerely,> Tracie> NS Co-owner/moderator> > > **************************************Tracie,Thank you for the information. Her Hemotalogist has diagnosed her withMyelosdyplastic.She is on so many different meds, Neurontin,Methadone, Prevacid, Valtrex,Zanaflex, just to name a few. They havetaken her off of Cytoxen and Prednisone. Two weeks ago she had fivetreatments of a new chemo, Dacogen. But her levels continued todecline, she has had 6 units of blood and 2 bags of platelets in threeweeks. She went in the hospital yesterday, more blood, the good newsis her platelets are back up to 23,000 and her hemoglobin is 11. Badnews her white cells are 0.002 and she has an infection, they have heron antibiotics. So we are hoping the white cells started going up alsoand the infection gets cleared up. Doc is hopeful that the chemo isworking, I hope do she has to go for five more treatments next week.We are just going day by day, it's all we can do! Thanks again forlistening to me. >

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,

It sounds like she has a ways to go, and it also sounds like her hematologist is on top of what she needs.

The prednisone and Cytoxan will wipe out the white cells- so she was compromised from them, then to get sick- takes alot out of you.

I'll have to read up on her dx-- I've heard of it, but not very familiar with it.

Take care-- of yourself also, I know that being the caregiver can be equally as tough as being the patient.

Sincerely,

Tracie

NS Co-owner/moderator************************************** See what's free at http://www.aol.com.

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Hello,

I just thought i should butt in and mention they i have had problems

with my bone marrow and sarcoidosis. I developed a disease called

TTP - Thrombotic Thrombocytopenia Purpura. It has in no way been

linked to sarcoidosis but i fell very ill with it last year and ended

up in ICU for a week. I don't think this is what your aunt has but i

do believe it was sparked by sarcodosis. I had a very low RCC,

Platlets, Haemoglobin etc. Do you know how low her platlets have

been? The other level called LD or LDH usually is increased

dramatically with TTP. Steroids can apparently help this problem.

Anyway i hope she is ok.

>

> ,

> It sounds like she has a ways to go, and it also sounds like her

hematologist

> is on top of what she needs.

> The prednisone and Cytoxan will wipe out the white cells- so she

was

> compromised from them, then to get sick- takes alot out of you.

> I'll have to read up on her dx-- I've heard of it, but not very

familiar with

> it.

>

> Take care-- of yourself also, I know that being the caregiver can

be equally

> as tough as being the patient.

>

> Sincerely,

> Tracie

> NS Co-owner/moderator

>

>

> **************************************

> See what's free

> at http://www.aol.com.

>

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