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Restless Legs Syndrome

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Dear Dawna,

I forgot to say that often it helps to make sure you're getting enough calcium, magnesium, and potassium late in the day. And as someone else said in response to your post, nix on the caffeine after lunch: at least that's my policy.

You'll be getting relief soon.

All the best,

Robyn

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  • 4 years later...

Hi Dolores,

Restless Legs Syndrome is common in adults with underlying neuromuscular

problems. Given mito is a neuromuscular related disease it would not be an

uncommon finding. The sleep lab where my girls have their studies done has

observed RLS in several teen swith mito or suspected mito. It is very uncommon

in children and teenagers. I don't know of any formal studies that have been

done in sleep medicine that have looked specifically at mitochondrial disease

and RLS. I suspect too few mito patients have been diagnosed at most sleep

centers for them to have the ability to do a formal study looking at this

specific process in this specific patient group for publication. They wouldn't

have the volume required to be statistically significant. On the other hand,

sleep abnormalities are very common although they seem to be a mix of

obstructive apnea, central apnea, hypoventilation, hypoxia, etc. These

abnormalities have all been reported and published (at least in some of the

critical

care journals). Both of our daughters receive ventilatory support durign sleep

because of sleep disordered breathing.

Joanne Kocourek (mom to , lies, and )

visit us at: http://www.caringbridge.org/il/annakris

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My son has restless leg syndrome. It's a neurological

problem. My boy is now 16. He's probably had it for

about five years, give or take. I think that

neurological problems are pretty common in mito.

Mom to the two best kids in the world!

http://www.caringbridge.org/visit/thomasandkatie

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Yahoo! Mail - PC Magazine Editors' Choice 2005

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Myoclonus can be misdiagnosed as restless leg, especially when it

occurs at night. The key seems to be the creepy crawly feeling that

makes it necessary to move the legs when relaxing. I have significant

myoclonus, even with treatment, but not RLS.

laurie

> Hi Dolores,

>

> Restless Legs Syndrome is common in adults with underlying neuromuscular

problems.

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I haven't done any reading about nighttime leg movements for several years,

but what I remember from previous reading suggested that periodic limb

movement disorder PLMD was the diagnosis for involuntary leg movements at

night when there was no neuromuscular disorder present to account for these

events. Restless leg syndrome was at that time defined as the night-time

creepy-crawly sensation that made one want to move the legs, but these

movements were voluntary in response to a neural sensation, not involuntary

twitches and jerks.

For us this issue arose when my hubby began having frequent strong jerks in

his legs at night, sometimes continuing for hours at a time. He was

completely unaware of them though they were strong enough to shake the bed

and wake me up--sometimes keeping ME awake for hours! He has no

neuromuscular disorders, thus the label benign PLMD. It turns out the

problem eventually resolved when he repaired his sleeping habits---he was

not getting enough sleep at the time, very sleep deprived. Once he paid his

sleep debt with 7+ hours sleep every night, the PLMD went away.

Anyway, at that time, they were differentiating between PLMD and RLS, the

former being involuntary night-time jerks and the latter night-time

voluntary movements in response to a neural sensation.

I have jerks in all muscles, legs included, anything from small twitches and

fasciculations to whole body myoclonic jerks, but no one has ever suggested

PLMD or RLS. In other words, for me the underlying neuromuscular disease

would account for them, day or night.

Barbara

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Thanks so much I really appreciate any info at all. Dolores

Joanne Kocourek servedogmom@...> wrote:Hi Dolores,

Restless Legs Syndrome is common in adults with underlying neuromuscular

problems. Given mito is a neuromuscular related disease it would not be an

uncommon finding. The sleep lab where my girls have their studies done has

observed RLS in several teen swith mito or suspected mito. It is very uncommon

in children and teenagers. I don't know of any formal studies that have been

done in sleep medicine that have looked specifically at mitochondrial disease

and RLS. I suspect too few mito patients have been diagnosed at most sleep

centers for them to have the ability to do a formal study looking at this

specific process in this specific patient group for publication. They wouldn't

have the volume required to be statistically significant. On the other hand,

sleep abnormalities are very common although they seem to be a mix of

obstructive apnea, central apnea, hypoventilation, hypoxia, etc. These

abnormalities have all been reported and published (at least in some of the

critical

care journals). Both of our daughters receive ventilatory support durign sleep

because of sleep disordered breathing.

Joanne Kocourek (mom to , lies, and )

visit us at: http://www.caringbridge.org/il/annakris

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> Thanks so much I really appreciate any info at all. Dolores

Dolores,

i agree with Laurie on the common misdiagnosis of myoclonus as RLS.

in my experience, people (MDs included), who don't understand the

difference between myoclonus, fibrillations and fasciculations call

any movement of the legs at night (even if they also occur during the

day) RLS. isn't it a shame that RLS is more well known than mito?

kent

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Kent,

You can lump Chronic Fatigue in there too. Many that have been misdx'ed

as having CFS find out later they have mito.

>isn't it a shame that RLS is more well known than mito?

>kent

>

>

>

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,

i suspect you are right.

CFS (or Myalgic Ecehalopathy, as I and many others prefer) has been my

diagnosis since 1999. but i know my body well enough and have found

out enough about mito and IBM that i suspect i don't have ME.

kent

> Kent,

>

> You can lump Chronic Fatigue in there too. Many that have been

misdx'ed

> as having CFS find out later they have mito.

>

>

>

> >isn't it a shame that RLS is more well known than mito?

> >kent

> >

> >

> >

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