Re: creatine/ dysautonia site

[Guest guest]

>It seems that more and more people are

> adding creatine to their mito cocktail. Is this recommended now? I',m

> wondering about trying it. (currently I take the Co Q, carnetine and B

> vits, plus lots of meds) How should I start it? Gradually? Are their

> any drug interactions to be careful about. Thanks again, Celia

" Creatine monohydrate is a substance synthesized in the human body and is

found in all meats. Creatine functions as an energy buffer/alternative

energy source in the cell, a weak but abundant antioxidant, and can protect

against ischemic injury in the brain.

Studies: Several small clinical trials in one case report have shown that

creatine supplementation can improve high intensity and aerobic exercise

performance, timed

exhaustion on a cycle ergometer, and some indicators of daily activity

performance. We have recently shown that creatine reversed paracrystalline

inclusions in the muscle of a patient with a cytochrome b mutation and that

creatine improved cell survival in cultured cells made from this patient

(Tarnopolsky, M.A., Muscle and Nerve, IN PRESS, 2004).Usual dose: 5 grams

per day; 0.1-0.15 grams/kg/day. "

http://www.umdf.org/library/UMDF%20Winter%202004.pdf

Quote from a lengthy article by Dr. Mark Tarnopolsky with thorough

discussion of many aspects of the mito cocktail, including a summary of the

clinical studies available for each. Written in easy-to-understand lay

language. He explains, among other things, why large scale studies have not

yet been done for these treatments.

He also says, " The decision to initiate therapy for mitochondrial disorders

and the choice of the agents must be made on a case by case basis and with

consultation from a physician with experience in the theory and practical

issues related to mitochondrial therapies. The purpose of this article is to

outline theoretical issues, clinical studies, and practical issues such as

doses and side effects of therapies for mitochondrial disorders. "

Barbara

[Guest guest]

I have never heard one way or the other from other people regarding

whether or not to go straight to the full daily dose or ramp up, but

myself, I have had to ramp up as I had problems starting with the full

dose. I have now started it with 1/4 of the dose to begin with now up

to 1/2 the dose. It has taken me two weeks to do this, but I haven't

had a problem with it so far this way. YMMV.

cghng888 wrote:

>Hi groupies, I hope everyone is feeling well today. I just have a

>couple of questions. Someone mentioned a good site for info about

>dyautonia (regarding my tachecardia) and I didn't take good enough

>note of it. Could you possibly post it again. many thanks in advance.

>aLSO A question about creatine. It seems that more and more people are

>adding creatine to their mito cocktail. Is this recommended now? I',m

>wondering about trying it. (currently I take the Co Q, carnetine and B

>vits, plus lots of meds) How should I start it? Gradually? Are their

>any drug interactions to be careful about. Thanks again, Celia

>

>

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