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I am going to start taking riboflavin, per my newest doctor's advice.

Anyone take it now? What dosage? Is it on the mito cocktail list?

I recall that B complex was on the list, and niacin, but don't

remember if riboflavin was on separately.

Has anyone found any chewable or liquid forms?

Thanks,

RH

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RH,

Dr. Cohen had me taking 400 mg's of B-2 in the morning and 200 mg's at night.

There are B complex vitamins but you won't find enough B-2 in there.

I haven't tried to find it in liquid of chewable, but you can find many in

liquid at Vitamin World---- some places it's called Puritan's Pride.

Cindy

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400 mg a day every day all at once. It has been a REAL important

addition for my daughter and I with our migraine headaches. Yes, it is

considered to be part of the mito cocktail by most. No chewable or

liquid that I am aware of. Another good thing about it, it is one of

the few cheap supplements suggested. It will make your pee bright

yellow and may have a strong odor the one time you go to the bathroom

after taking the dose.

ohgminion wrote:

>I am going to start taking riboflavin, per my newest doctor's advice.

>Anyone take it now? What dosage? Is it on the mito cocktail list?

>

>I recall that B complex was on the list, and niacin, but don't

>remember if riboflavin was on separately.

>

>Has anyone found any chewable or liquid forms?

>

>Thanks,

>RH

>

>

>

>

>

>

>Medical advice, information, opinions, data and statements contained herein are

not necessarily those of the list moderators. The author of this e mail is

entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with their

physicians regarding changes in their own treatment.

>

>Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

>

>

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Riboflavin has been a part of the mito cocktail since the 80s. I started

taking riboflavin in 1988 at the suggestion of Wortmann, MD, a

metabolic myopathy expert. At that time there were a few reports in the

literature about riboflavin helping patients with defects in beta oxidation

(which I have). It is cofactor for a number of beta oxidation pathways. I

had a remarkable response to riboflavin and have not heard of any other

patient with this response. In 1988 I was having attacks of muscle breakdown

on average one every ten days. Milder attacks were incapacitating for 3-4

days, more severe ones took weeks to recover. Obviously, sometimes I didn't

fully recover before the next one hit. When I started riboflavin, I had NO

attacks of muscle breakdown for 6 months. This had never happened before. I

also had a major reduction in muscle pain (best pain pill I've ever had!)

and increased strength and activity tolerance. Riboflavin saved my

functional life at that time. It did NOT halt progression, but it put me way

back up the hill. I also have to credit riboflavin for opening the door to

further testing for OXPHOS and ultimately the second diagnosis. As you know,

riboflavin is also a cofactor for OXPHOS pathways, and partly because I was

so riboflavin-responsive, I was urged to have another muscle biopsy. My son

also responded remarkably to riboflavin and it allowed him to complete his

education.

Wortmann and others set up some studies for me to document the biochemical

effects of the riboflavin, along with Carnitor. Each was studied separately

through a 3-biopsy study, pre and post treatment. Riboflavin did

significantly increase my ATP and nucleotides in muscle, though both

remained well below normal.

We also did some informal, unpublished studies re riboflavin and my

glucose/insulin response. Off ribo, my GTT glucose and insulin levels are

abnormally high. On ribo the upper end of the glucose curve normalized,

though it still dropped to 30 something at 4 hours. My hyperinsulinism also

was significantly reduced, though still many times higher than normal. There

are reports of a few other patients with beta oxidation defects, such as

glutaric aciduria, where riboflavin has either normalized or greatly

improved an abnormal glucose curve.

Possibly we are unusually response to riboflavin because we have a broad

mitochondrial defect that impairs many pathways, and ribo is a cofactor for

many of those pathways. Boosting those impaired pathways clearly benefited

us in a major way. (It does not help with my migraines, however.)

Hope you get at least some help. Definitely worth a try, and I have rarely

heard of adverse reactions.

Barbara

> Riboflavin - vitamin B2

>

> I am going to start taking riboflavin, per my newest doctor's advice.

> Anyone take it now? What dosage? Is it on the mito cocktail list?

>

> I recall that B complex was on the list, and niacin, but don't

> remember if riboflavin was on separately.

>

> Has anyone found any chewable or liquid forms?

>

> Thanks,

> RH

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Hi,

The only place I've found plain B2 was at GNC...it was also surprisingly cheap

there too....like $4 for a bottle of 100 or more. From the replies to your

question....it looks like we need to increase Dewayne's dosage. Take care.

Lynda R.

Riboflavin - vitamin B2

I am going to start taking riboflavin, per my newest doctor's advice.

Anyone take it now? What dosage? Is it on the mito cocktail list?

I recall that B complex was on the list, and niacin, but don't

remember if riboflavin was on separately.

Has anyone found any chewable or liquid forms?

Thanks,

RH

Medical advice, information, opinions, data and statements contained herein

are not necessarily those of the list moderators. The author of this e mail is

entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with their

physicians regarding changes in their own treatment.

Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

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I order mine from Puritan's Pride.

rose farm wrote:

>Hi,

>The only place I've found plain B2 was at GNC...it was also surprisingly cheap

there too....like $4 for a bottle of 100 or more. From the replies to your

question....it looks like we need to increase Dewayne's dosage. Take care.

>Lynda R.

> Riboflavin - vitamin B2

>

>

> I am going to start taking riboflavin, per my newest doctor's advice.

> Anyone take it now? What dosage? Is it on the mito cocktail list?

>

> I recall that B complex was on the list, and niacin, but don't

> remember if riboflavin was on separately.

>

> Has anyone found any chewable or liquid forms?

>

> Thanks,

> RH

>

>

>

>

>

> Medical advice, information, opinions, data and statements contained herein

are not necessarily those of the list moderators. The author of this e mail is

entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with their

physicians regarding changes in their own treatment.

>

> Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

>

>

>

>

>

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I buy Optimum and special order them a dozen at a time through our Wal-Mart

pharmacy. They can get them overnight or in 2 days. Optimum is manufactured

by Magno-Humphries. We chose this brand because they seem to have fewer

binders and break down more quickly for absorption. You can buy them online

but then you pay shipping.

http://www.magno-humphries.com/categories.asp?a=r&Id=2

Barbara

> Re: Riboflavin - vitamin B2

>

> I order mine from Puritan's Pride.

>

>

> rose farm wrote:

>

> >Hi,

> >The only place I've found plain B2 was at GNC...it was also surprisingly

cheap

> there too....like $4 for a bottle of 100 or more. From the replies to

your question....it

> looks like we need to increase Dewayne's dosage. Take care.

> >Lynda R.

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Thank you (and others) so much for the info! I guess I'm a bit

afraid because B-100 complex gave me a problem, but I certainly

understand that taking it separately could be a great thing for me.

Take care,

RH

>

> Riboflavin has been a part of the mito cocktail since the 80s. I

started

> taking riboflavin in 1988 at the suggestion of Wortmann, MD,

a

> metabolic myopathy expert. At that time there were a few reports in

the

> literature about riboflavin helping patients with defects in beta

oxidation

> (which I have). It is cofactor for a number of beta oxidation

pathways. I

> had a remarkable response to riboflavin and have not heard of any

other

> patient with this response. In 1988 I was having attacks of muscle

breakdown

> on average one every ten days. Milder attacks were incapacitating

for 3-4

> days, more severe ones took weeks to recover. Obviously, sometimes

I didn't

> fully recover before the next one hit. When I started riboflavin, I

had NO

> attacks of muscle breakdown for 6 months. This had never happened

before. I

> also had a major reduction in muscle pain (best pain pill I've ever

had!)

> and increased strength and activity tolerance. Riboflavin saved my

> functional life at that time. It did NOT halt progression, but it

put me way

> back up the hill. I also have to credit riboflavin for opening the

door to

> further testing for OXPHOS and ultimately the second diagnosis. As

you know,

> riboflavin is also a cofactor for OXPHOS pathways, and partly

because I was

> so riboflavin-responsive, I was urged to have another muscle

biopsy. My son

> also responded remarkably to riboflavin and it allowed him to

complete his

> education.

>

> Wortmann and others set up some studies for me to document the

biochemical

> effects of the riboflavin, along with Carnitor. Each was studied

separately

> through a 3-biopsy study, pre and post treatment. Riboflavin did

> significantly increase my ATP and nucleotides in muscle, though both

> remained well below normal.

>

> We also did some informal, unpublished studies re riboflavin and my

> glucose/insulin response. Off ribo, my GTT glucose and insulin

levels are

> abnormally high. On ribo the upper end of the glucose curve

normalized,

> though it still dropped to 30 something at 4 hours. My

hyperinsulinism also

> was significantly reduced, though still many times higher than

normal. There

> are reports of a few other patients with beta oxidation defects,

such as

> glutaric aciduria, where riboflavin has either normalized or greatly

> improved an abnormal glucose curve.

>

> Possibly we are unusually response to riboflavin because we have a

broad

> mitochondrial defect that impairs many pathways, and ribo is a

cofactor for

> many of those pathways. Boosting those impaired pathways clearly

benefited

> us in a major way. (It does not help with my migraines, however.)

>

> Hope you get at least some help. Definitely worth a try, and I have

rarely

> heard of adverse reactions.

>

> Barbara

>

> > Riboflavin - vitamin B2

> >

> > I am going to start taking riboflavin, per my newest doctor's

advice.

> > Anyone take it now? What dosage? Is it on the mito cocktail

list?

> >

> > I recall that B complex was on the list, and niacin, but don't

> > remember if riboflavin was on separately.

> >

> > Has anyone found any chewable or liquid forms?

> >

> > Thanks,

> > RH

>

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B2 is in B 50 Complex, but only 50 mg. My girls currently take 200 mg of B2

four times/day and B 50 Complex twice/day. The high dose B2 has made a

significant difference in the number of migraine headaches they get.

MitomomX3@... wrote:Is B2 in the B5o

Joanne Kocourek (mom to , lies, and )

visit us at: http://www.caringbridge.org/il/annakris

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FYI, I had a problem with B-50 and B-100 also. Not sure which B or whether

it was the combo.

Barbara

> Thank you (and others) so much for the info! I guess I'm a bit

> afraid because B-100 complex gave me a problem, but I certainly

> understand that taking it separately could be a great thing for me.

>

> Take care,

> RH

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http://www.swansonvitamins.com/

is my favorite for price and availability, including more expensive stuff.

Swanson Premium Brand [store-brand, their cheapest, in green plastic

bottles]

Vitamin B-2 (Riboflavin) Item# SW018 100 Mg 100 Caps $2.39

Steve D.

> Date: Thu, 20 Oct 2005 15:21:49 -0700

>

> Subject: Re: Riboflavin - vitamin B2

>

> I order mine from Puritan's Pride.

>

>

> rose farm wrote:

>

>>Hi,

>>The only place I've found plain B2 was at GNC...it was also surprisingly

>>cheap there too....like $4 for a bottle of 100 or more. From the replies

>>to your question....it looks like we need to increase Dewayne's dosage.

>>Take care.

>>Lynda R.

>> Riboflavin - vitamin B2

>>

>>

>> I am going to start taking riboflavin, per my newest doctor's advice.

>> Anyone take it now? What dosage? Is it on the mito cocktail list?

>>

>> I recall that B complex was on the list, and niacin, but don't

>> remember if riboflavin was on separately.

>>

>> Has anyone found any chewable or liquid forms?

>>

>> Thanks,

>> RH

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The doc who diagnosed me I am supposed to take 100 mg three times a day. I

seldom do just because I am not good at taking stuff and have mild symptoms.

But it, the Qgel, and Carnitor do help greatly when I take them along with the

1000 mg vitamin C I am supposed to take four times a day.

Someone on the mito kids list posted that they get a liquid cherry flavored

riboflavin. she posted the name of the I believe manufacturer. I cannot find

it in my email though--it was posted a couple of days ago or even a week ago.

Janet Sample

Riboflavin - vitamin B2

I am going to start taking riboflavin, per my newest doctor's advice.

Anyone take it now? What dosage? Is it on the mito cocktail list?

I recall that B complex was on the list, and niacin, but don't

remember if riboflavin was on separately.

Has anyone found any chewable or liquid forms?

Thanks,

RH

Medical advice, information, opinions, data and statements contained herein

are not necessarily those of the list moderators. The author of this e mail is

entirely responsible for its content. List members are reminded of their

responsibility to evaluate the content of the postings and consult with their

physicians regarding changes in their own treatment.

Personal attacks are not permitted on the list and anyone who sends one is

automatically moderated or removed depending on the severity of the attack.

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Share on other sites

Thank you Janet, I found this, it sounds similar but not sure if it

is the same thing:

http://www.amazon.com/exec/obidos/tg/detail/-/B0001ITURA/103-3567420-

0036606?v=glance

Here is the company's website (company is HoneyCombs Industries),

they sell a lot of single vitamins in liquid form.

https://secure5.nexternal.com/shared/StoreFront/default.asp?

CS=honeycombs&BusType=BtoC&Count1=232341945&Count2=149482369&CategoryI

D=2&Target=products.asp

100 mg three times a day seems like a lot according to the RDA (yes,

I know RDA's are notoriously low and of course we are treating a

medical condition). I'll probably start on 100 mg total per day.

I did see on their website that you can buy 1, 8, or 16 oz. of it (I

only saw 1 oz. available through Amazon). There are 408 mg/ounce.

There's a lot of glycerine in it, I wonder if that would increase

motility a bit (or too much LOL).

I also found B2 powder from LEF:

http://www.lef.org/newshop/items/item00092.html

Sounds like the powder might be more cost-effective (and amenable if

anyone would want it for tube feeding).

Thanks,

RH

>

> The doc who diagnosed me I am supposed to take 100 mg three times a

day. I seldom do just because I am not good at taking stuff and have

mild symptoms. But it, the Qgel, and Carnitor do help greatly when I

take them along with the 1000 mg vitamin C I am supposed to take four

times a day.

>

> Someone on the mito kids list posted that they get a liquid cherry

flavored riboflavin. she posted the name of the I believe

manufacturer. I cannot find it in my email though--it was posted a

couple of days ago or even a week ago.

>

> Janet Sample

> Riboflavin - vitamin B2

>

>

> I am going to start taking riboflavin, per my newest doctor's

advice.

> Anyone take it now? What dosage? Is it on the mito cocktail

list?

>

> I recall that B complex was on the list, and niacin, but don't

> remember if riboflavin was on separately.

>

> Has anyone found any chewable or liquid forms?

>

> Thanks,

> RH

>

>

>

>

>

> Medical advice, information, opinions, data and statements

contained herein are not necessarily those of the list moderators.

The author of this e mail is entirely responsible for its content.

List members are reminded of their responsibility to evaluate the

content of the postings and consult with their physicians regarding

changes in their own treatment.

>

> Personal attacks are not permitted on the list and anyone who

sends one is automatically moderated or removed depending on the

severity of the attack.

>

>

>

>

>

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RH

Just some more info on subject. Several docs recommend 400mg of B2 to

help with migraines. I take mine all at once. Large doses cause the

urine to be very yellow and smell, so most I know take it at dinner or

bedtime to be able to get rid of the smelly urine before meeting the

world.

I spoke with a researcher from CA who is now in MI. He researched B2

as a migraine proventer. He said that they used amounts as high as

1200 mg. He said it seems to either work or not work, but is safer

than the meds they usually use if it does work.

I'm not suggesting that anyone do any of this without a doctor's input.

laurie

> Thank you Janet, I found this, it sounds similar but not sure if it

> is the same thing:

>

> http://www.amazon.com/exec/obidos/tg/detail/-/B0001ITURA/103-3567420-

> 0036606?v=glance

>

> Here is the company's website (company is HoneyCombs Industries),

> they sell a lot of single vitamins in liquid form.

>

> https://secure5.nexternal.com/shared/StoreFront/default.asp?

> CS=honeycombs&BusType=BtoC&Count1=232341945&Count2=149482369&CategoryI

> D=2&Target=products.asp

>

> 100 mg three times a day seems like a lot according to the RDA (yes,

> I know RDA's are notoriously low and of course we are treating a

> medical condition). I'll probably start on 100 mg total per day.

>

> I did see on their website that you can buy 1, 8, or 16 oz. of it (I

> only saw 1 oz. available through Amazon). There are 408 mg/ounce.

> There's a lot of glycerine in it, I wonder if that would increase

> motility a bit (or too much LOL).

>

> I also found B2 powder from LEF:

> http://www.lef.org/newshop/items/item00092.html

>

> Sounds like the powder might be more cost-effective (and amenable if

> anyone would want it for tube feeding).

>

> Thanks,

> RH

>

>

>

> >

> > The doc who diagnosed me I am supposed to take 100 mg three times a

> day. I seldom do just because I am not good at taking stuff and have

> mild symptoms. But it, the Qgel, and Carnitor do help greatly when I

> take them along with the 1000 mg vitamin C I am supposed to take four

> times a day.

> >

> > Someone on the mito kids list posted that they get a liquid cherry

> flavored riboflavin. she posted the name of the I believe

> manufacturer. I cannot find it in my email though--it was posted a

> couple of days ago or even a week ago.

> >

> > Janet Sample

> > Riboflavin - vitamin B2

> >

> >

> > I am going to start taking riboflavin, per my newest doctor's

> advice.

> > Anyone take it now? What dosage? Is it on the mito cocktail

> list?

> >

> > I recall that B complex was on the list, and niacin, but don't

> > remember if riboflavin was on separately.

> >

> > Has anyone found any chewable or liquid forms?

> >

> > Thanks,

> > RH

> >

> >

> >

> >

> >

> > Medical advice, information, opinions, data and statements

> contained herein are not necessarily those of the list moderators.

> The author of this e mail is entirely responsible for its content.

> List members are reminded of their responsibility to evaluate the

> content of the postings and consult with their physicians regarding

> changes in their own treatment.

> >

> > Personal attacks are not permitted on the list and anyone who

> sends one is automatically moderated or removed depending on the

> severity of the attack.

> >

> >

> >

> >

> >

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Thanks Laurie, Dr. Garganta (Dr. Korson's colleague) at NEMC told me

to try taking riboflavin, but didn't give me any guidelines, I am

waiting to hear about test results from her soon. I'll make sure to

ask her how much to take, I think I can wait until I hear about my

results.

Take care,

RH

>

> RH

>

> Just some more info on subject. Several docs recommend 400mg of B2

to

> help with migraines. I take mine all at once. Large doses cause the

> urine to be very yellow and smell, so most I know take it at dinner

or

> bedtime to be able to get rid of the smelly urine before meeting the

> world.

>

> I spoke with a researcher from CA who is now in MI. He researched B2

> as a migraine proventer. He said that they used amounts as high as

> 1200 mg. He said it seems to either work or not work, but is safer

> than the meds they usually use if it does work.

>

> I'm not suggesting that anyone do any of this without a doctor's

input.

>

> laurie

>

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Hi RH,

As you know I am a patient of Dr. Korson's and he told me to

continue to take the B2.

It was my MDA Neuro who first put me on the B2. When I saw Dr. Korson

he increased my dosage. I am now taking up to 600mgs. It really helps

keep my migraines at bay, it doesn't stop them completely, but they

have decreased. I have been on B2 for almost 4 yrs. now.

You can always email or call Dr. Garganta and ask her what dosage she

wants you

to start at, if you think it might be awhile until your test results are back.

Hugs,

Ann-Marie

At 12:07 PM 10/28/2005, you wrote:

>Thanks Laurie, Dr. Garganta (Dr. Korson's colleague) at NEMC told me

>to try taking riboflavin, but didn't give me any guidelines, I am

>waiting to hear about test results from her soon. I'll make sure to

>ask her how much to take, I think I can wait until I hear about my

>results.

>

>Take care,

>RH

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