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Sounds as if your friend is having a bad time of it. She needs to concentrate

on the fact that this is going to be a temporary situation.

She has been in the hospital more than she's been out since her operation and

although they just checked to make sure everything's OK, she did have a second

operation when they reopened her. It is no wonder she is without any appetite.

It is very common to be able to take in only a couple sips of water at a time at

the beginning, it is like she is beginning all over again. She should have a

water bottle with her constantly and sip all day. She is probably on a soft

diet, so soup is good to sip on as much as possible. Chicken egg drop soup adds

some extra protein.

She should eat every 2 or 3 hours also, don't drink any water for about 1/2 hour

before eating so the stomach is empty.

An open incision isn't fun, but if she follows instructions, it'll be fine.

Also since she is probably on antibiotics, she should eat yougurt with the live

cultures.

Rita Black

Open DS Dr. Macura 4/28/01

<My friend had her open ds on July 2nd with Dr. Macura of Staten

Island. Since then, she's been hospitalized twice. The first time,

they didn't know what was wrong with her so they reopened her

incision to see if it was surgery related - it wasn't. She spent 2

weeks in ICU and the doctor's didn't know what was wrong with her.

They treated her for TSS (toxic shock syndrome) and sent her home.

Now she's back in the hospital (4 days after being released) because

her incision started to reopen. Anyway, she's complaining of having

NO APPETITE. Of getting full after 2 sips of water and SERIOUSLY

regretting the whole surgery.>

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Sounds as if your friend is having a bad time of it. She needs to concentrate

on the fact that this is going to be a temporary situation.

She has been in the hospital more than she's been out since her operation and

although they just checked to make sure everything's OK, she did have a second

operation when they reopened her. It is no wonder she is without any appetite.

It is very common to be able to take in only a couple sips of water at a time at

the beginning, it is like she is beginning all over again. She should have a

water bottle with her constantly and sip all day. She is probably on a soft

diet, so soup is good to sip on as much as possible. Chicken egg drop soup adds

some extra protein.

She should eat every 2 or 3 hours also, don't drink any water for about 1/2 hour

before eating so the stomach is empty.

An open incision isn't fun, but if she follows instructions, it'll be fine.

Also since she is probably on antibiotics, she should eat yougurt with the live

cultures.

Rita Black

Open DS Dr. Macura 4/28/01

<My friend had her open ds on July 2nd with Dr. Macura of Staten

Island. Since then, she's been hospitalized twice. The first time,

they didn't know what was wrong with her so they reopened her

incision to see if it was surgery related - it wasn't. She spent 2

weeks in ICU and the doctor's didn't know what was wrong with her.

They treated her for TSS (toxic shock syndrome) and sent her home.

Now she's back in the hospital (4 days after being released) because

her incision started to reopen. Anyway, she's complaining of having

NO APPETITE. Of getting full after 2 sips of water and SERIOUSLY

regretting the whole surgery.>

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  • 10 months later...
Guest guest

I too am driving to distraction by the itchiness. After years of use

of different products and I'm sure I am not done yet, I am currently

using the rosacea care cleanser and will soon start the rosacea

disks. I have tried the Sy products and I like them too. I

believe that my sensitivity has increased over the years by too much

product use. All the prescription creams just seemed to increase my

itchiness so about a year ago I stopped all use of them. So then it

was on to finding something on my own that would not irritate my

skin. Bar soaps seem to be the worst ofender. Had a severe reaction

to the Cetaphil soap that was recommened to use with the disks. So

now am preparing my skin by just using the rosacea care cleanser and

waiting for the itchiness and inflamations to subside before starting

on the disks. So my advice to you is go slow and it really is a

trial and error for everyone's different skin types and different

reactions to various products. The old adage of what works for one

rosacean does not work for the other rosacean is so true. Cindy

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  • 1 year later...

1. I have fought weight most of my life. SA

2. I use to feel ashamed around other people. SD

3. It was hard for me to look into the mirror. D

4. I used to secretly eat. D

5. I felt my physical and mental health suffered. A

6. I felt like I was always dieting. SA

7. When I dieted, I gained it all back, plus some. SA

8. I felt that I tried every other option available to me. SA

9. Food was my escape from life and reality. SD

10. I thoroughly researched Bariatric Surgery. SA

11. I was/am ready to commit to a better way of life. SA

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1. I have fought weight most of my life. SA

2. I use to feel ashamed around other people. SD

3. It was hard for me to look into the mirror. D

4. I used to secretly eat. D

5. I felt my physical and mental health suffered. A

6. I felt like I was always dieting. SA

7. When I dieted, I gained it all back, plus some. SA

8. I felt that I tried every other option available to me. SA

9. Food was my escape from life and reality. SD

10. I thoroughly researched Bariatric Surgery. SA

11. I was/am ready to commit to a better way of life. SA

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> I am doing a research class in my degree program and need to get

> some answers from anyone that will help me out. I won't be using

> any names so don't worry that you will be giving information that

> others may see. This survey is how people felt before surgery. .

> Please answer the following questions in this manner so that I may

> collect accurate information for my report. SA, A, D, SD, or DA,

at

> the end of each stated sentence.

>

> Strongly agree Agree Disagree Strongly disagree Doesn't

apply

> (SA) (A) (D) (SD) (DA)

>

> 1. I have fought weight most of my life. A

>

> 2. I use to feel ashamed around other people. SA

>

> 3. It was hard for me to look into the mirror. SA

>

> 4. I used to secretly eat. A

>

> 5. I felt my physical and mental health suffered. SA

>

> 6. I felt like I was always dieting. A

>

> 7. When I dieted, I gained it all back, plus some. SA

>

> 8. I felt that I tried every other option available to me. SA

>

> 9. Food was my escape from life and reality. A

>

> 10. I thoroughly researched Bariatric Surgery. A

>

> 11. I was/am ready to commit to a better way of life. SA

>

> Thank you in advance for your help.

>

> Tammy

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> I am doing a research class in my degree program and need to get

> some answers from anyone that will help me out. I won't be using

> any names so don't worry that you will be giving information that

> others may see. This survey is how people felt before surgery. .

> Please answer the following questions in this manner so that I may

> collect accurate information for my report. SA, A, D, SD, or DA,

at

> the end of each stated sentence.

>

> Strongly agree Agree Disagree Strongly disagree Doesn't

apply

> (SA) (A) (D) (SD) (DA)

>

> 1. I have fought weight most of my life. A

>

> 2. I use to feel ashamed around other people. SA

>

> 3. It was hard for me to look into the mirror. SA

>

> 4. I used to secretly eat. A

>

> 5. I felt my physical and mental health suffered. SA

>

> 6. I felt like I was always dieting. A

>

> 7. When I dieted, I gained it all back, plus some. SA

>

> 8. I felt that I tried every other option available to me. SA

>

> 9. Food was my escape from life and reality. A

>

> 10. I thoroughly researched Bariatric Surgery. A

>

> 11. I was/am ready to commit to a better way of life. SA

>

> Thank you in advance for your help.

>

> Tammy

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In a message dated 2/22/2004 6:24:25 PM Eastern Standard Time,

tammy_s1959@... writes:

I am doing a research class in my degree program and need to get

some answers from anyone that will help me out. I won't be using

any names so don't worry that you will be giving information that

others may see. This survey is how people felt before surgery. .

Please answer the following questions in this manner so that I may

collect accurate information for my report. SA, A, D, SD, or DA, at

the end of each stated sentence.

Strongly agree Agree Disagree Strongly disagree Doesn't apply

(SA) (A) (D) (SD) (DA)

1. I have fought weight most of my life. A

2. I use to feel ashamed around other people. A

3. It was hard for me to look into the mirror. SA

4. I used to secretly eat. A

5. I felt my physical and mental health suffered. A

6. I felt like I was always dieting. A

7. When I dieted, I gained it all back, plus some. SA

8. I felt that I tried every other option available to me. A

9. Food was my escape from life and reality. A

10. I thoroughly researched Bariatric Surgery. A

11. I was/am ready to commit to a better way of life. SA

Thank you in advance for your help.

Tammy

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In a message dated 2/22/2004 6:24:25 PM Eastern Standard Time,

tammy_s1959@... writes:

I am doing a research class in my degree program and need to get

some answers from anyone that will help me out. I won't be using

any names so don't worry that you will be giving information that

others may see. This survey is how people felt before surgery. .

Please answer the following questions in this manner so that I may

collect accurate information for my report. SA, A, D, SD, or DA, at

the end of each stated sentence.

Strongly agree Agree Disagree Strongly disagree Doesn't apply

(SA) (A) (D) (SD) (DA)

1. I have fought weight most of my life. A

2. I use to feel ashamed around other people. A

3. It was hard for me to look into the mirror. SA

4. I used to secretly eat. A

5. I felt my physical and mental health suffered. A

6. I felt like I was always dieting. A

7. When I dieted, I gained it all back, plus some. SA

8. I felt that I tried every other option available to me. A

9. Food was my escape from life and reality. A

10. I thoroughly researched Bariatric Surgery. A

11. I was/am ready to commit to a better way of life. SA

Thank you in advance for your help.

Tammy

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  • 1 year later...
Guest guest

Hi - I remember you from amitys. :) I've actually been

thinking about you and Emma alot lately and wondering how to get in

contact with you again.

I'm sorry to hear that Emma hasn't been doing well- we go through

phases with Lea with ups and downs for no apparent reason. To me the

episodes you are describing sound alot like seizures. Has she had

seizures in the past? Another thing that came to mind with the

drooling-- have you noticed any stroke-like episodes?

Hope you find some answers very soon!

le and Lea, living with partial complex 1

and 6 other very healthy kiddos

> Ive been a member off and on for the last 3 years, but recently

there have been some changes with my daughter. I am not sure how

many of you remember Emma (www.emmas2hearts.com) She is 3, almost 4,

and is a heart transplant patient with complex 1 and 3. (diagnosed

after transplant)

>

> We have been doing amazingly well, no set backs whatsover. We

almost forgot that she was sick. Over the last 3 weeks things have

changed. It started with just behavior, we chalked it up to

terrible 3's. Then it turned into not sleeping, and now things have

gotten really odd.

>

> She doesnt sleep. She is going on about 3 hours of sleep a day.

She is also making repetitive sounds all night long, similar to what

tourrets patient do. Her speech has also become somewhat slurred,

and she has regressed to sucking her thumb and drooling (although

not all the time). Emma was a typical 3 year old up until this all

started less than a month ago.

>

> We have met with her geneticist/mito doctor. He believes that she

is having seizures, we are trying to get in for an EEG next week.

What else could this be? It is like she has periods of the " old

emma " and then other times she is almost in a daze, just wondering

around the house. She has times where she is very verbal, then she

has times where she doesnt speak, or she repeats the same sounds

over and over (she laid in bed last night and repeated the same

sequence of sounds for 3 hours)

>

> Any thoughts would be greatly appreciated. She is starting Adavan

tonight to help sleep, and hopefully the EEG will shine some light

on this, although I have heard that they dont always come out

accurate. Our next step is an MRI, but right now I am very

concerned about the changes I have seen in my little girl.

>

> Thank you for reading this, any response would be greatly

appreciated.

>

>

> www.emmas2hearts.com

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  • 8 months later...

My neurologist suspects that I am suffering from an unknown mitochondrial

disease. I am very depressed and worried. Can anyone provide me with the contact

address (preferably email address ), of some experts in mitochondrial disorders.

Regards,

MQ

pamelama33 pamelama33@...> wrote: Hi Joanne - here's my experience

with cardiac arrhythmias (palpitations, tachycardia, fibrillation etc). They

started one day when I was in my mid twenties. Doctors were not concerned as

said it was a common thing. When I was 28 and had my first child I had trouble

breastfeeding but was encouraged by Nursing Mothers to just keep on feeding and

the milk would come. I took it to extreme and had my baby on the breast almost

all the time (and still could not produce enough (Mito??)) Anyway during that

period I had the most shocking palpitations which I put down to the extra stress

my body was experiencing during that period. My whole body would shake and

heart pounding sometimes up to an hour at a time. As it was coming on blood

would rush into my neck and my head would get dizzy so I knew it was coming on.

Resting would not help . I felt nauseated but moving around was better, but

nothing stopped it till it was ready to stop. Over

the years the palpitations continued (doctors not concerned), no telling what

triggered them, except that I noticed sometimes they would start when I had bent

over say to tie shoelaces and straightened up after that, and I could sometimes

stop them by holding my breath and going back down again for a while, and after

a while coming up slowly while exhaling.

I am 56 now and at this age doctors have been more concerned when palpitations

have occurred, as they have said there is more likelihood for blockages like

plaque in the arteries. I had a bad episode and went to the doc several years

ago but wouldn't you know it it stopped just as I was sitting down in the chair.

He sent me to a cardiologist who gave me exercise stress test and echo which

were normal (exercise was not normally a trigger so this was not really a good

test though). So they said don wurry be appy. So I threw myself into my high

stress IT job, but when I worked for long hours my heart would start pounding.

Two months later I had a heart attack and was in intensive coronary care for

three days. Angiogram showed clear arteries so they were all completely

confused as my heart was in spasm (still four years later ECG shows damage). It

was called coronary artery spasm, and one called it tako tsubo syndrome although

current cardio says it was due to high cholesterol and

plaque not evident at the time .

I don't know if the heart attack had anything to do with the palpitations. I

had atrial fibrillation recorded during the infarction (but not the worse one

ventricular fibrillation). I was put on heaps of medications including statins

and couldnt tolerate (now know why). I still had pounding episodes during

periods of stress (either physical or emotional) and caught one episode of

atrial fibrillation on a 24-hour monitor so cardio now has me on Isoptin

(Verapamil) 120mg. ( I also take Questran and Ezetrol for cholesterol). The

Isoptin seems to have stopped the arrhythmia - I can sometimes feel it wanting

to come on but it doesn't continue. I think Isoptin lowers blood pressure but

not sure so it may just be for certain people.

I don't know if any of this helps. Now I know I have mito (Melas) I can't help

but think they are all connected. I feel continuing stress is a factor (and

certainly was for my infarct), although as you say one often " feels " relaxed

when they start. Maybe its a conduction malfunction which I understand can be

part of mito (and according to what I have read, a pacemaker may rectify this).

Since you do have this problem I would recommend keeping a close eye on your

body's cholesterol levels. I also am interested to hear of other cardiac

stories. pamela

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Hi Pamela,

OK, I will ask a specific question. Do any of you have optic nerve atrophy. I

was diagnosed with this condition in 1995, but it is only now that my vision is

declining very fast. Besides, this I have hearng loss, ataxia and peripheral

neuropathy.

I want to know how long will it take for my vision to be lost completely or

how long before I can no longer read. I am very depressed .

Can alternative treatment like acupuncture help my vision?

Is stem cell treatment an option in mitochondrial disorders.

Since my doctor says that I am suffering from an unknown mito disease, many of

you may not have similar symptoms.

Regards

MQ

pamelama33 pamelama33@...> wrote: Hi MQ - I am fairly new but this

forum is a wealth of information - ask specific questions and you will get

responses. If you want a doctor to respond you can email the Ask the Mito Doc

on the UMDF site, at www.umdf.org/MitoDoc.aspx pamela

please help

My neurologist suspects that I am suffering from an unknown mitochondrial

disease. I am very depressed and worried. Can anyone provide me with the contact

address (preferably email address ), of some experts in mitochondrial disorders.

Regards,

MQ

pamelama33 pamelama33@...> wrote: Hi Joanne - here's my experience

with cardiac arrhythmias (palpitations, tachycardia, fibrillation etc). They

started one day when I was in my mid twenties. Doctors were not concerned as

said it was a common thing. When I was 28 and had my first child I had trouble

breastfeeding but was encouraged by Nursing Mothers to just keep on feeding and

the milk would come. I took it to extreme and had my baby on the breast almost

all the time (and still could not produce enough (Mito??)) Anyway during that

period I had the most shocking palpitations which I put down to the extra stress

my body was experiencing during that period. My whole body would shake and

heart pounding sometimes up to an hour at a time. As it was coming on blood

would rush into my neck and my head would get dizzy so I knew it was coming on.

Resting would not help . I felt nauseated but moving around was better, but

nothing stopped it till it was ready to stop. Over

the years the palpitations continued (doctors not concerned), no telling what

triggered them, except that I noticed sometimes they would start when I had bent

over say to tie shoelaces and straightened up after that, and I could sometimes

stop them by holding my breath and going back down again for a while, and after

a while coming up slowly while exhaling.

I am 56 now and at this age doctors have been more concerned when palpitations

have occurred, as they have said there is more likelihood for blockages like

plaque in the arteries. I had a bad episode and went to the doc several years

ago but wouldn't you know it it stopped just as I was sitting down in the chair.

He sent me to a cardiologist who gave me exercise stress test and echo which

were normal (exercise was not normally a trigger so this was not really a good

test though). So they said don wurry be appy. So I threw myself into my high

stress IT job, but when I worked for long hours my heart would start pounding.

Two months later I had a heart attack and was in intensive coronary care for

three days. Angiogram showed clear arteries so they were all completely

confused as my heart was in spasm (still four years later ECG shows damage). It

was called coronary artery spasm, and one called it tako tsubo syndrome although

current cardio says it was due to high cholesterol

and

plaque not evident at the time .

I don't know if the heart attack had anything to do with the palpitations. I

had atrial fibrillation recorded during the infarction (but not the worse one

ventricular fibrillation). I was put on heaps of medications including statins

and couldnt tolerate (now know why). I still had pounding episodes during

periods of stress (either physical or emotional) and caught one episode of

atrial fibrillation on a 24-hour monitor so cardio now has me on Isoptin

(Verapamil) 120mg. ( I also take Questran and Ezetrol for cholesterol). The

Isoptin seems to have stopped the arrhythmia - I can sometimes feel it wanting

to come on but it doesn't continue. I think Isoptin lowers blood pressure but

not sure so it may just be for certain people.

I don't know if any of this helps. Now I know I have mito (Melas) I can't

help but think they are all connected. I feel continuing stress is a factor

(and certainly was for my infarct), although as you say one often " feels "

relaxed when they start. Maybe its a conduction malfunction which I understand

can be part of mito (and according to what I have read, a pacemaker may rectify

this). Since you do have this problem I would recommend keeping a close eye

on your body's cholesterol levels. I also am interested to hear of other

cardiac stories. pamela

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What part of the country are you in? How far are you willing to travel?

Most of the mito docs do NOT correspond with patients via email (several are

at facilities that prohibit it). I'd be happy to supply names and geographic

locations privately. If that would help, let me know.

medical question mark medical_questionmark@...> wrote:

My neurologist suspects that I am suffering from an unknown mitochondrial

disease. I am very depressed and worried. Can anyone provide me with the

contact address (preferably email address ), of some experts in mitochondrial

disorders.

Regards,

MQ

pamelama33 pamelama33@...> wrote: Hi Joanne - here's my experience

with cardiac arrhythmias (palpitations, tachycardia, fibrillation etc). They

started one day when I was in my mid twenties. Doctors were not concerned as

said it was a common thing. When I was 28 and had my first child I had

trouble breastfeeding but was encouraged by Nursing Mothers to just keep on

feeding and the milk would come. I took it to extreme and had my baby on the

breast almost all the time (and still could not produce enough (Mito??))

Anyway during that period I had the most shocking palpitations which I put down

to the extra stress my body was experiencing during that period. My whole body

would shake and heart pounding sometimes up to an hour at a time. As it was

coming on blood would rush into my neck and my head would get dizzy so I knew

it was coming on. Resting would not help . I felt nauseated but moving around

was better, but nothing stopped it till it was ready

to stop. Over

the years the palpitations continued (doctors not concerned), no telling what

triggered them, except that I noticed sometimes they would start when I had

bent over say to tie shoelaces and straightened up after that, and I could

sometimes stop them by holding my breath and going back down again for a while,

and after a while coming up slowly while exhaling.

I am 56 now and at this age doctors have been more concerned when

palpitations have occurred, as they have said there is more likelihood for

blockages like plaque in the arteries. I had a bad episode and went to the doc

several years ago but wouldn't you know it it stopped just as I was sitting

down in the chair. He sent me to a cardiologist who gave me exercise stress

test and echo which were normal (exercise was not normally a trigger so this

was not really a good test though). So they said don wurry be appy. So I

threw myself into my high stress IT job, but when I worked for long hours my

heart would start pounding. Two months later I had a heart attack and was in

intensive coronary care for three days. Angiogram showed clear arteries so

they were all completely confused as my heart was in spasm (still four years

later ECG shows damage). It was called coronary artery spasm, and one called

it tako tsubo syndrome although current cardio says it was due to high

cholesterol and

plaque not evident at the time .

I don't know if the heart attack had anything to do with the palpitations. I

had atrial fibrillation recorded during the infarction (but not the worse one

ventricular fibrillation). I was put on heaps of medications including statins

and couldnt tolerate (now know why). I still had pounding episodes during

periods of stress (either physical or emotional) and caught one episode of

atrial fibrillation on a 24-hour monitor so cardio now has me on Isoptin

(Verapamil) 120mg. ( I also take Questran and Ezetrol for cholesterol). The

Isoptin seems to have stopped the arrhythmia - I can sometimes feel it wanting

to come on but it doesn't continue. I think Isoptin lowers blood pressure but

not sure so it may just be for certain people.

I don't know if any of this helps. Now I know I have mito (Melas) I can't

help but think they are all connected. I feel continuing stress is a factor

(and certainly was for my infarct), although as you say one often " feels "

relaxed when they start. Maybe its a conduction malfunction which I understand

can be part of mito (and according to what I have read, a pacemaker may rectify

this). Since you do have this problem I would recommend keeping a close eye

on your body's cholesterol levels. I also am interested to hear of other

cardiac stories. pamela

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I don't know if any of the adults on this list have optic nerve atrophy but I

do know several of the children on the general mito list do. My girls

(teen/young adults) both have peripheral neuropathy, hearing loss and

intermittent ataxia. My 20 year old has vision issues that seem to be related

to the lack of energy. The last time she saw her Neuro-ophthamologist he

indicated that in the context of mitochondrial disease he could NOT predict the

rate of progression of vision loss. Some days are good and others are not.

I have never heard that acupuncture is a treatment for visual preservation.

Stem cell research is still far in the future in the context of mitochondrial

disease. General gene therapy is being used on a very limited RESEARCH basis

for several of the other diseases in the dystrophy family. Note: the results

have been far from promising across the board in the dystrophies. Solid organ

transplants have been done successfully incarefully selected patients with

mitochondrial disase.

I can understand the resultant depression. Are you being helped? The mito

maze and all of the implications are difficult to swallow. Sometimes being

proactive can help. You know what you cannot change. Can you look ahead in

regards to what you can do to accommodate to the changes? Example: my girls

have service dogs to respond to apnea, monitor/ventilator alarms, balance

support, etc. We have introduced training for " hearing alert " tasks as there

are sounds we don't want the girls to miss when their hearing is not as acute.

medical question mark medical_questionmark@...> wrote: Hi

Pamela,

OK, I will ask a specific question. Do any of you have optic nerve atrophy.

I was diagnosed with this condition in 1995, but it is only now that my vision

is declining very fast. Besides, this I have hearng loss, ataxia and peripheral

neuropathy.

I want to know how long will it take for my vision to be lost completely or

how long before I can no longer read. I am very depressed .

Can alternative treatment like acupuncture help my vision?

Is stem cell treatment an option in mitochondrial disorders.

Since my doctor says that I am suffering from an unknown mito disease, many

of you may not have similar symptoms.

Regards

MQ

Joanne Kocourek (mom to , lies, and )

visit us at: http://www.caringbridge.org/il/annakris

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MQ,

Regarding finding a doctor through UMDF, I wanted to mention that when

I did that, the doctors they referred me to were not doctors that

anyone else on this list said they went to. Also, the hospital they

were at was not one that the people on this list said they go to and

trust (at least with mito; otherwise, it was a fine hospital). It is

not clear to me that the names that UMDF offers are ones that they

have actual exprience with or not. If you get names from them, you

might want to check with this group and see if other people have had

experience with those doctors.

Hi Joanne - here's my

experience with cardiac arrhythmias (palpitations, tachycardia,

fibrillation etc). They started one day when I was in my mid

twenties. Doctors were not concerned as said it was a common thing.

When I was 28 and had my first child I had trouble breastfeeding but

was encouraged by Nursing Mothers to just keep on feeding and the milk

would come. I took it to extreme and had my baby on the breast almost

all the time (and still could not produce enough (Mito??)) Anyway

during that period I had the most shocking palpitations which I put

down to the extra stress my body was experiencing during that period.

My whole body would shake and heart pounding sometimes up to an hour

at a time. As it was coming on blood would rush into my neck and my

head would get dizzy so I knew it was coming on. Resting would not

help . I felt nauseated but moving around was better, but nothing

stopped it till it was ready to stop. Over

> the years the palpitations continued (doctors not concerned), no

telling what triggered them, except that I noticed sometimes they

would start when I had bent over say to tie shoelaces and straightened

up after that, and I could sometimes stop them by holding my breath

and going back down again for a while, and after a while coming up

slowly while exhaling.

>

> I am 56 now and at this age doctors have been more concerned when

palpitations have occurred, as they have said there is more likelihood

for blockages like plaque in the arteries. I had a bad episode and

went to the doc several years ago but wouldn't you know it it stopped

just as I was sitting down in the chair. He sent me to a cardiologist

who gave me exercise stress test and echo which were normal (exercise

was not normally a trigger so this was not really a good test though).

So they said don wurry be appy. So I threw myself into my high

stress IT job, but when I worked for long hours my heart would start

pounding. Two months later I had a heart attack and was in intensive

coronary care for three days. Angiogram showed clear arteries so they

were all completely confused as my heart was in spasm (still four

years later ECG shows damage). It was called coronary artery spasm,

and one called it tako tsubo syndrome although current cardio says it

was due to high cholesterol and

> plaque not evident at the time .

>

> I don't know if the heart attack had anything to do with the

palpitations. I had atrial fibrillation recorded during the

infarction (but not the worse one ventricular fibrillation). I was

put on heaps of medications including statins and couldnt tolerate

(now know why). I still had pounding episodes during periods of

stress (either physical or emotional) and caught one episode of atrial

fibrillation on a 24-hour monitor so cardio now has me on Isoptin

(Verapamil) 120mg. ( I also take Questran and Ezetrol for

cholesterol). The Isoptin seems to have stopped the arrhythmia - I

can sometimes feel it wanting to come on but it doesn't continue. I

think Isoptin lowers blood pressure but not sure so it may just be for

certain people.

>

> I don't know if any of this helps. Now I know I have mito (Melas) I

can't help but think they are all connected. I feel continuing

stress is a factor (and certainly was for my infarct), although as you

say one often " feels " relaxed when they start. Maybe its a conduction

malfunction which I understand can be part of mito (and according to

what I have read, a pacemaker may rectify this). Since you do have

this problem I would recommend keeping a close eye on your body's

cholesterol levels. I also am interested to hear of other cardiac

stories. pamela

>

>

>

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I have never been told that I have optic atrophy, but that my retinas aRE

DEGENERATING. I also have right sided deafness. My retinal specialist doesn't

know if my retina degeneration is related to the mito or not because he doesn't

have anyone to compare me to. medical

question mark medical_questionmark@...> wrote: Hi Pamela,

OK, I will ask a specific question. Do any of you have optic nerve atrophy. I

was diagnosed with this condition in 1995, but it is only now that my vision is

declining very fast. Besides, this I have hearng loss, ataxia and peripheral

neuropathy.

I want to know how long will it take for my vision to be lost completely or

how long before I can no longer read. I am very depressed .

Can alternative treatment like acupuncture help my vision?

Is stem cell treatment an option in mitochondrial disorders.

Since my doctor says that I am suffering from an unknown mito disease, many of

you may not have similar symptoms.

Regards

MQ

pamelama33 pamelama33@...> wrote: Hi MQ - I am fairly new but this

forum is a wealth of information - ask specific questions and you will get

responses. If you want a doctor to respond you can email the Ask the Mito Doc

on the UMDF site, at www.umdf.org/MitoDoc.aspx pamela

please help

My neurologist suspects that I am suffering from an unknown mitochondrial

disease. I am very depressed and worried. Can anyone provide me with the contact

address (preferably email address ), of some experts in mitochondrial disorders.

Regards,

MQ

pamelama33 pamelama33@...> wrote: Hi Joanne - here's my experience

with cardiac arrhythmias (palpitations, tachycardia, fibrillation etc). They

started one day when I was in my mid twenties. Doctors were not concerned as

said it was a common thing. When I was 28 and had my first child I had trouble

breastfeeding but was encouraged by Nursing Mothers to just keep on feeding and

the milk would come. I took it to extreme and had my baby on the breast almost

all the time (and still could not produce enough (Mito??)) Anyway during that

period I had the most shocking palpitations which I put down to the extra stress

my body was experiencing during that period. My whole body would shake and

heart pounding sometimes up to an hour at a time. As it was coming on blood

would rush into my neck and my head would get dizzy so I knew it was coming on.

Resting would not help . I felt nauseated but moving around was better, but

nothing stopped it till it was ready to stop. Over

the years the palpitations continued (doctors not concerned), no telling what

triggered them, except that I noticed sometimes they would start when I had bent

over say to tie shoelaces and straightened up after that, and I could sometimes

stop them by holding my breath and going back down again for a while, and after

a while coming up slowly while exhaling.

I am 56 now and at this age doctors have been more concerned when palpitations

have occurred, as they have said there is more likelihood for blockages like

plaque in the arteries. I had a bad episode and went to the doc several years

ago but wouldn't you know it it stopped just as I was sitting down in the chair.

He sent me to a cardiologist who gave me exercise stress test and echo which

were normal (exercise was not normally a trigger so this was not really a good

test though). So they said don wurry be appy. So I threw myself into my high

stress IT job, but when I worked for long hours my heart would start pounding.

Two months later I had a heart attack and was in intensive coronary care for

three days. Angiogram showed clear arteries so they were all completely

confused as my heart was in spasm (still four years later ECG shows damage). It

was called coronary artery spasm, and one called it tako tsubo syndrome although

current cardio says it was due to high cholesterol

and

plaque not evident at the time .

I don't know if the heart attack had anything to do with the palpitations. I

had atrial fibrillation recorded during the infarction (but not the worse one

ventricular fibrillation). I was put on heaps of medications including statins

and couldnt tolerate (now know why). I still had pounding episodes during

periods of stress (either physical or emotional) and caught one episode of

atrial fibrillation on a 24-hour monitor so cardio now has me on Isoptin

(Verapamil) 120mg. ( I also take Questran and Ezetrol for cholesterol). The

Isoptin seems to have stopped the arrhythmia - I can sometimes feel it wanting

to come on but it doesn't continue. I think Isoptin lowers blood pressure but

not sure so it may just be for certain people.

I don't know if any of this helps. Now I know I have mito (Melas) I can't

help but think they are all connected. I feel continuing stress is a factor

(and certainly was for my infarct), although as you say one often " feels "

relaxed when they start. Maybe its a conduction malfunction which I understand

can be part of mito (and according to what I have read, a pacemaker may rectify

this). Since you do have this problem I would recommend keeping a close eye

on your body's cholesterol levels. I also am interested to hear of other

cardiac stories. pamela

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  • 1 month later...
Guest guest

Hello,

Thanks friends for replying back.

Actually I live in outside USA, India. My neurologist says that I am suffering

from an unknown mitochondrial disorder, though he is not sure. He says that we

could reach a definite diagnosis if a detailed genetic analysis is carried out,

which is a expensive test, and may only be possible in the US. And even if the

diagnosis is made, there is no cure.

I have some questions to ask.

Has anyone undergone a detailed genetic analysis, and what is the cost.

For Joanne, I have specific question. Since your girls have similar symptoms

like me, peripheral neuropathy, hearing lossand intermittent ataxia, and vision

problems, it is possible that my condition is similar to theirs. Can u let me

know the name of the disease they are suffering from.

Please also let me know the address of the general mito list.

Regards

MQ

Joanne Kocourek servedogmom@...> wrote: I don't know if any of the

adults on this list have optic nerve atrophy but I do know several of the

children on the general mito list do. My girls (teen/young adults) both have

peripheral neuropathy, hearing loss and intermittent ataxia. My 20 year old

has vision issues that seem to be related to the lack of energy. The last time

she saw her Neuro-ophthamologist he indicated that in the context of

mitochondrial disease he could NOT predict the rate of progression of vision

loss. Some days are good and others are not.

I have never heard that acupuncture is a treatment for visual preservation.

Stem cell research is still far in the future in the context of mitochondrial

disease. General gene therapy is being used on a very limited RESEARCH basis

for several of the other diseases in the dystrophy family. Note: the results

have been far from promising across the board in the dystrophies. Solid organ

transplants have been done successfully incarefully selected patients with

mitochondrial disase.

I can understand the resultant depression. Are you being helped? The mito

maze and all of the implications are difficult to swallow. Sometimes being

proactive can help. You know what you cannot change. Can you look ahead in

regards to what you can do to accommodate to the changes? Example: my girls

have service dogs to respond to apnea, monitor/ventilator alarms, balance

support, etc. We have introduced training for " hearing alert " tasks as there

are sounds we don't want the girls to miss when their hearing is not as acute.

medical question mark medical_questionmark@...> wrote: Hi

Pamela,

OK, I will ask a specific question. Do any of you have optic nerve atrophy.

I was diagnosed with this condition in 1995, but it is only now that my vision

is declining very fast. Besides, this I have hearng loss, ataxia and peripheral

neuropathy.

I want to know how long will it take for my vision to be lost completely or

how long before I can no longer read. I am very depressed .

Can alternative treatment like acupuncture help my vision?

Is stem cell treatment an option in mitochondrial disorders.

Since my doctor says that I am suffering from an unknown mito disease, many

of you may not have similar symptoms.

Regards

MQ

Joanne Kocourek (mom to , lies, and )

visit us at: http://www.caringbridge.org/il/annakris

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Guest guest

First, very few individuals with a diagnosis of mitochondrial disease actually

know the genetic abnormality (the last I heard was around 15% total between

blood and muscle studies). We do NOT know the specific genetic defect in my

girls. This is what we do know: they have abnormalities in Complex I, III, IV

and ANT function. They also have issues with the metabolism of fat that are

secondary to mitochondrial disease. One of the physician is doing a study of

the entire mitochondrial genome for my girls. He has had the tissue sample over

three years and we still have no results. THe cost, if it was not being done

onm a research basis, would be well into the $100,000 range (US).

Second: While it is true that there is NO cure. There is treatment that may

slow the progression of the disease in soem individuals. My girls definitely

feel better when taking the mito cocktail.

The general mito list is one of the yahoo groups called mito. (You will find

in in the same search where you likely found .

medical question mark medical_questionmark@...> wrote:

Hello,

Thanks friends for replying back.

Actually I live in outside USA, India. My neurologist says that I am suffering

from an unknown mitochondrial disorder, though he is not sure. He says that we

could reach a definite diagnosis if a detailed genetic analysis is carried out,

which is a expensive test, and may only be possible in the US. And even if the

diagnosis is made, there is no cure.

I have some questions to ask.

Has anyone undergone a detailed genetic analysis, and what is the cost.

For Joanne, I have specific question. Since your girls have similar symptoms

like me, peripheral neuropathy, hearing lossand intermittent ataxia, and vision

problems, it is possible that my condition is similar to theirs. Can u let me

know the name of the disease they are suffering from.

Please also let me know the address of the general mito list.

Joanne Kocourek (mom to , lies, and )

visit us at: http://www.caringbridge.org/il/annakris

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Share on other sites

Guest guest

How did the doctors conclude that your girls had abnormalities in Complex I,

III, IV and ANT function. What tests were performed?

My neurologist has prescribed vitamin e, vitamin b ,vitamin c and CQ10. I

have read that the mito cocktail also includes other vitamins also. What kind

ofvitamins and other supplements do your girls take.

I did not have much problem with my vision until recently, when I went on a

low carb diet. Prior to this I had suffered from an eye infection, it is only

now that I have come to know that mito disease sufferers should eat three

regular meals.

Can you let me know the names of institutes in US, where such genetic

analysis is done on a research basis,

Have your girls ever tried any alternative medicine

Regards

Mq

Joanne Kocourek servedogmom@...> wrote: First, very few individuals with

a diagnosis of mitochondrial disease actually know the genetic abnormality (the

last I heard was around 15% total between blood and muscle studies). We do NOT

know the specific genetic defect in my girls. This is what we do know: they

have abnormalities in Complex I, III, IV and ANT function. They also have

issues with the metabolism of fat that are secondary to mitochondrial disease.

One of the physician is doing a study of the entire mitochondrial genome for my

girls. He has had the tissue sample over three years and we still have no

results. THe cost, if it was not being done onm a research basis, would be well

into the $100,000 range (US).

Second: While it is true that there is NO cure. There is treatment that may

slow the progression of the disease in soem individuals. My girls definitely

feel better when taking the mito cocktail.

The general mito list is one of the yahoo groups called mito. (You will find

in in the same search where you likely found .

medical question mark medical_questionmark@...> wrote:

Hello,

Thanks friends for replying back.

Actually I live in outside USA, India. My neurologist says that I am suffering

from an unknown mitochondrial disorder, though he is not sure. He says that we

could reach a definite diagnosis if a detailed genetic analysis is carried out,

which is a expensive test, and may only be possible in the US. And even if the

diagnosis is made, there is no cure.

I have some questions to ask.

Has anyone undergone a detailed genetic analysis, and what is the cost.

For Joanne, I have specific question. Since your girls have similar symptoms

like me, peripheral neuropathy, hearing lossand intermittent ataxia, and vision

problems, it is possible that my condition is similar to theirs. Can u let me

know the name of the disease they are suffering from.

Please also let me know the address of the general mito list.

Joanne Kocourek (mom to , lies, and )

visit us at: http://www.caringbridge.org/il/annakris

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Share on other sites

Guest guest

The diagnosis was obtained by skin fibroblast studies and fresh muscle biopsies.

(Multiple).

My girls take the following: Coenzyme Q10 (very high doses), Carnitor, Vit E,

High dose riboflavin, B50 Complex, Vit C, Niacinamide, Selenium, Alpha Lipoic

Acid, a mulitvitamin, and multiple meds to address each of the affected organ

systems. This is considered a component of alternative medicine. Over time

we've tried guided imagry, biofeedback, massage, etc without any improvement.

They are on a high, complex carb, very low fat diet with 5-6 smaller meals each

day and lots of oral fluids (3,000-3500cc).

AS far as I know the genetics studies are being done in Atlanta, UC Irvine,

possibly Columbia and UCSF.

medical question mark medical_questionmark@...> wrote:

How did the doctors conclude that your girls had abnormalities in Complex I,

III, IV and ANT function. What tests were performed?

What kind ofvitamins and other supplements do your girls take.

I did not have much problem with my vision until recently, when I went on a

low carb diet. Prior to this I had suffered from an eye infection, it is only

now that I have come to know that mito disease sufferers should eat three

regular meals.

Can you let me know the names of institutes in US, where such genetic analysis

is done on a research basis,

Have your girls ever tried any alternative medicine

Joanne Kocourek (mom to , lies, and )

visit us at: http://www.caringbridge.org/il/annakris

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Share on other sites

Guest guest

Thanks a lot for answering my questions,

I will be asking doctors in India, if I could benefit from a skin and muscle

biopsy.

I have also read that mitochondrial diseases can affect any organ any time.

How true is that?

Also, that many mito diseases are characterizd by mental retardation and

cognitive involvement . could we say that one day my intellectual

capabilities may be affected.

Are your girls still studying or have they entered the worforce.

I am a writer-working from home. Please give my best to youdaughters .

I will be praying for them.

Regards

Mq

Joanne Kocourek servedogmom@...> wrote: The diagnosis was obtained by

skin fibroblast studies and fresh muscle biopsies. (Multiple).

My girls take the following: Coenzyme Q10 (very high doses), Carnitor, Vit E,

High dose riboflavin, B50 Complex, Vit C, Niacinamide, Selenium, Alpha Lipoic

Acid, a mulitvitamin, and multiple meds to address each of the affected organ

systems. This is considered a component of alternative medicine. Over time

we've tried guided imagry, biofeedback, massage, etc without any improvement.

They are on a high, complex carb, very low fat diet with 5-6 smaller meals each

day and lots of oral fluids (3,000-3500cc).

AS far as I know the genetics studies are being done in Atlanta, UC Irvine,

possibly Columbia and UCSF.

medical question mark medical_questionmark@...> wrote:

How did the doctors conclude that your girls had abnormalities in Complex I,

III, IV and ANT function. What tests were performed?

What kind ofvitamins and other supplements do your girls take.

I did not have much problem with my vision until recently, when I went on a

low carb diet. Prior to this I had suffered from an eye infection, it is only

now that I have come to know that mito disease sufferers should eat three

regular meals.

Can you let me know the names of institutes in US, where such genetic analysis

is done on a research basis,

Have your girls ever tried any alternative medicine

Joanne Kocourek (mom to , lies, and )

visit us at: http://www.caringbridge.org/il/annakris

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Share on other sites

Guest guest

MQ

When the number of normally functioning mitochondria goes below that

level needed to function properly, then that organ system begins to

mal-function. This is my belief - taking the mito cocktail (lots of

antioxidents) helps to protect the good mitochondria from being

damaged and maintains function longer.

Mental retardation is more apt to be found in children as far as I

understand. There are those with specific defects (in adults and

children) that are more apt to get dementia. Since the aging process

is due to damage and inadequate functioning of the mitochondria, early

aging of the brain is possible. Some of us have problems with finding

the word we want to use as easily as we would like, but the rest of

our brains work fine. Loosing my mental functioning is one of my

greatest fears.

laurie

>

>

> Thanks a lot for answering my questions,

> I will be asking doctors in India, if I could benefit from a skin and

> muscle biopsy.

>

> I have also read that mitochondrial diseases can affect any organ any

> time. How true is that?

>

> Also, that many mito diseases are characterizd by mental retardation and

> cognitive involvement . could we say that one day my intellectual

> capabilities may be affected.

>

> Are your girls still studying or have they entered the worforce.

>

> I am a writer-working from home. Please give my best to youdaughters .

>

> I will be praying for them.

>

> Regards

> Mq

>

> Joanne Kocourek servedogmom@...> wrote: The diagnosis was obtained

> by skin fibroblast studies and fresh muscle biopsies. (Multiple).

>

>

> My girls take the following: Coenzyme Q10 (very high doses), Carnitor, Vit

> E, High dose riboflavin, B50 Complex, Vit C, Niacinamide, Selenium, Alpha

> Lipoic Acid, a mulitvitamin, and multiple meds to address each of the

> affected organ systems. This is considered a component of alternative

> medicine. Over time we've tried guided imagry, biofeedback, massage, etc

> without any improvement.

>

> They are on a high, complex carb, very low fat diet with 5-6 smaller meals

> each day and lots of oral fluids (3,000-3500cc).

>

> AS far as I know the genetics studies are being done in Atlanta, UC Irvine,

> possibly Columbia and UCSF.

>

> medical question mark medical_questionmark@...> wrote:

> How did the doctors conclude that your girls had abnormalities in

> Complex I, III, IV and ANT function. What tests were performed?

>

> What kind ofvitamins and other supplements do your girls take.

>

>

> I did not have much problem with my vision until recently, when I went

> on a low carb diet. Prior to this I had suffered from an eye infection, it

> is only now that I have come to know that mito disease sufferers should eat

> three regular meals.

>

> Can you let me know the names of institutes in US, where such genetic

> analysis is done on a research basis,

>

> Have your girls ever tried any alternative medicine

>

>

>

>

>

> Joanne Kocourek (mom to , lies, and )

> visit us at: http://www.caringbridge.org/il/annakris

>

>

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Guest guest

Laurie, I feel the same way. I have been battling this

dementia for awhile now. Plus I have thyroid

problems,which also does not help with the brain

functioning properly. But since I feel the melas

(mito) problem is getting worse, I can't comprehend,I

say things that are totally off the wall,can't think

about certain things,and I can't remember much.It has

taken away my love for reading, etc. I can't fill out

the simplest of forms.So I fear for the loss also. I

am not a child and believe me it is very hard to

except. I do childrens books, trying to keep up some

part of my brain working.

--- Laurie Fitzgerald laurie.fitzgerald@...>

wrote:

> MQ

>

> When the number of normally functioning mitochondria

> goes below that

> level needed to function properly, then that organ

> system begins to

> mal-function. This is my belief - taking the mito

> cocktail (lots of

> antioxidents) helps to protect the good mitochondria

> from being

> damaged and maintains function longer.

>

> Mental retardation is more apt to be found in

> children as far as I

> understand. There are those with specific defects

> (in adults and

> children) that are more apt to get dementia. Since

> the aging process

> is due to damage and inadequate functioning of the

> mitochondria, early

> aging of the brain is possible. Some of us have

> problems with finding

> the word we want to use as easily as we would like,

> but the rest of

> our brains work fine. Loosing my mental functioning

> is one of my

> greatest fears.

>

> laurie

>

> On 3/3/06, medical question mark

> medical_questionmark@...> wrote:

> >

> >

> > Thanks a lot for answering my questions,

> > I will be asking doctors in India, if I could

> benefit from a skin and

> > muscle biopsy.

> >

> > I have also read that mitochondrial diseases

> can affect any organ any

> > time. How true is that?

> >

> > Also, that many mito diseases are characterizd

> by mental retardation and

> > cognitive involvement . could we say that one

> day my intellectual

> > capabilities may be affected.

> >

> > Are your girls still studying or have they

> entered the worforce.

> >

> > I am a writer-working from home. Please give my

> best to youdaughters .

> >

> > I will be praying for them.

> >

> > Regards

> > Mq

> >

> > Joanne Kocourek servedogmom@...> wrote:

> The diagnosis was obtained

> > by skin fibroblast studies and fresh muscle

> biopsies. (Multiple).

> >

> >

> > My girls take the following: Coenzyme Q10 (very

> high doses), Carnitor, Vit

> > E, High dose riboflavin, B50 Complex, Vit C,

> Niacinamide, Selenium, Alpha

> > Lipoic Acid, a mulitvitamin, and multiple meds to

> address each of the

> > affected organ systems. This is considered a

> component of alternative

> > medicine. Over time we've tried guided imagry,

> biofeedback, massage, etc

> > without any improvement.

> >

> > They are on a high, complex carb, very low fat

> diet with 5-6 smaller meals

> > each day and lots of oral fluids (3,000-3500cc).

> >

> > AS far as I know the genetics studies are being

> done in Atlanta, UC Irvine,

> > possibly Columbia and UCSF.

> >

> > medical question mark

> medical_questionmark@...> wrote:

> > How did the doctors conclude that your girls

> had abnormalities in

> > Complex I, III, IV and ANT function. What tests

> were performed?

> >

> > What kind ofvitamins and other supplements do

> your girls take.

> >

> >

> > I did not have much problem with my vision

> until recently, when I went

> > on a low carb diet. Prior to this I had suffered

> from an eye infection, it

> > is only now that I have come to know that mito

> disease sufferers should eat

> > three regular meals.

> >

> > Can you let me know the names of institutes in

> US, where such genetic

> > analysis is done on a research basis,

> >

> > Have your girls ever tried any alternative

> medicine

> >

> >

> >

> >

> >

> > Joanne Kocourek (mom to , lies, and

> )

> > visit us at:

> http://www.caringbridge.org/il/annakris

> >

> > [Non-text portions of this message have been

> removed]

> >

> >

> >

> > Medical advice, information, opinions, data and

> statements contained herein

> > are not necessarily those of the list moderators.

> The author of this e mail

> > is entirely responsible for its content. List

> members are reminded of their

> > responsibility to evaluate the content of the

> postings and consult with

> > their physicians regarding changes in their own

> treatment.

> >

> > Personal attacks are not permitted on the list

> and anyone who sends one is

> > automatically moderated or removed depending on

> the severity of the attack.

> >

> >

> >

> >

> >

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Guest guest

Irene

I admire your determination and your gift to write children's books. I

have tried my hand at writing and illustrating early phonic books for

my students, and it is not an easy task.

Does saving your energy by sitting to do things and taking a nap help

with the mental function?

I'll keep you in my thoughts,

laurie

> Laurie, I feel the same way. I have been battling this

> dementia for awhile now. Plus I have thyroid

> problems,which also does not help with the brain

> functioning properly. But since I feel the melas

> (mito) problem is getting worse, I can't comprehend,I

> say things that are totally off the wall,can't think

> about certain things,and I can't remember much.It has

> taken away my love for reading, etc. I can't fill out

> the simplest of forms.So I fear for the loss also. I

> am not a child and believe me it is very hard to

> except. I do childrens books, trying to keep up some

> part of my brain working.

>

> --- Laurie Fitzgerald laurie.fitzgerald@...>

>

> wrote:

>

> > MQ

> >

> > When the number of normally functioning mitochondria

> > goes below that

> > level needed to function properly, then that organ

> > system begins to

> > mal-function. This is my belief - taking the mito

> > cocktail (lots of

> > antioxidents) helps to protect the good mitochondria

> > from being

> > damaged and maintains function longer.

> >

> > Mental retardation is more apt to be found in

> > children as far as I

> > understand. There are those with specific defects

> > (in adults and

> > children) that are more apt to get dementia. Since

> > the aging process

> > is due to damage and inadequate functioning of the

> > mitochondria, early

> > aging of the brain is possible. Some of us have

> > problems with finding

> > the word we want to use as easily as we would like,

> > but the rest of

> > our brains work fine. Loosing my mental functioning

> > is one of my

> > greatest fears.

> >

> > laurie

> >

> > On 3/3/06, medical question mark

> > medical_questionmark@...> wrote:

> > >

> > >

> > > Thanks a lot for answering my questions,

> > > I will be asking doctors in India, if I could

> > benefit from a skin and

> > > muscle biopsy.

> > >

> > > I have also read that mitochondrial diseases

> > can affect any organ any

> > > time. How true is that?

> > >

> > > Also, that many mito diseases are characterizd

> > by mental retardation and

> > > cognitive involvement . could we say that one

> > day my intellectual

> > > capabilities may be affected.

> > >

> > > Are your girls still studying or have they

> > entered the worforce.

> > >

> > > I am a writer-working from home. Please give my

> > best to youdaughters .

> > >

> > > I will be praying for them.

> > >

> > > Regards

> > > Mq

> > >

> > > Joanne Kocourek servedogmom@...> wrote:

> > The diagnosis was obtained

> > > by skin fibroblast studies and fresh muscle

> > biopsies. (Multiple).

> > >

> > >

> > > My girls take the following: Coenzyme Q10 (very

> > high doses), Carnitor, Vit

> > > E, High dose riboflavin, B50 Complex, Vit C,

> > Niacinamide, Selenium, Alpha

> > > Lipoic Acid, a mulitvitamin, and multiple meds to

> > address each of the

> > > affected organ systems. This is considered a

> > component of alternative

> > > medicine. Over time we've tried guided imagry,

> > biofeedback, massage, etc

> > > without any improvement.

> > >

> > > They are on a high, complex carb, very low fat

> > diet with 5-6 smaller meals

> > > each day and lots of oral fluids (3,000-3500cc).

> > >

> > > AS far as I know the genetics studies are being

> > done in Atlanta, UC Irvine,

> > > possibly Columbia and UCSF.

> > >

> > > medical question mark

> > medical_questionmark@...> wrote:

> > > How did the doctors conclude that your girls

> > had abnormalities in

> > > Complex I, III, IV and ANT function. What tests

> > were performed?

> > >

> > > What kind ofvitamins and other supplements do

> > your girls take.

> > >

> > >

> > > I did not have much problem with my vision

> > until recently, when I went

> > > on a low carb diet. Prior to this I had suffered

> > from an eye infection, it

> > > is only now that I have come to know that mito

> > disease sufferers should eat

> > > three regular meals.

> > >

> > > Can you let me know the names of institutes in

> > US, where such genetic

> > > analysis is done on a research basis,

> > >

> > > Have your girls ever tried any alternative

> > medicine

> > >

> > >

> > >

> > >

> > >

> > > Joanne Kocourek (mom to , lies, and

> > )

> > > visit us at:

> > http://www.caringbridge.org/il/annakris

> > >

> > > [Non-text portions of this message have been

> > removed]

> > >

> > >

> > >

> > > Medical advice, information, opinions, data and

> > statements contained herein

> > > are not necessarily those of the list moderators.

> > The author of this e mail

> > > is entirely responsible for its content. List

> > members are reminded of their

> > > responsibility to evaluate the content of the

> > postings and consult with

> > > their physicians regarding changes in their own

> > treatment.

> > >

> > > Personal attacks are not permitted on the list

> > and anyone who sends one is

> > > automatically moderated or removed depending on

> > the severity of the attack.

> > >

> > >

> > >

> > >

> > >

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  • 2 weeks later...
Guest guest

Hello everyone,

It is Wanda from Australia here, I haven't posted lately due to very ill

health and 2 Hospital visits.

I am so new to these groups, I marvel at how you can banter around your

great knowledge for the benefit of us still learning.

My Mito is progressing and has been like this for 6 months now. I have had 3

Muscle biopsies (2 needle and one large muscle) My diagnosis has alterd over

6 1/2 years due to technology in the DNA testing procedures. I was given the

initial diagnosis of Mitochondrial Myopathy in 1998 but since seeing my

latest Neurologist and having a new biopsy she has told me it is

Mitochondrial Cytopathy. I have seen my test and it said numerous cox

negative fibres and " ragged red " fibres with type 2B fibre atrophy.

COX1gene-nucleotide position 5904-7445

reveals a G-A change in position 6261 and C-T change in position 7028.

Cytochrome B Oxidase deficiency.

Some fresh and some frozen testing was done and is still being done on

frozen muscle in the future.

To a layman it is so confusing being that their are so many variations of

this disease. All I know is that I now need a shower chair a walking stick

and a wheelchair for outside journeys.

I do hope that we can get to know each other in the future and I hope to

hear from you all,and if anyone else has similar testing results I would

love to hear from you.

Stay safe

Regards Wanda

>

>Reply-To:

>To:

>Subject: Re: please help

>Date: Thu, 2 Mar 2006 16:23:14 -0800 (PST)

>

>The diagnosis was obtained by skin fibroblast studies and fresh muscle

>biopsies. (Multiple).

>

>My girls take the following: Coenzyme Q10 (very high doses), Carnitor, Vit

>E, High dose riboflavin, B50 Complex, Vit C, Niacinamide, Selenium, Alpha

>Lipoic Acid, a mulitvitamin, and multiple meds to address each of the

>affected organ systems. This is considered a component of alternative

>medicine. Over time we've tried guided imagry, biofeedback, massage, etc

>without any improvement.

>

>They are on a high, complex carb, very low fat diet with 5-6 smaller meals

>each day and lots of oral fluids (3,000-3500cc).

>

>AS far as I know the genetics studies are being done in Atlanta, UC Irvine,

>possibly Columbia and UCSF.

>

>medical question mark medical_questionmark@...> wrote:

> How did the doctors conclude that your girls had abnormalities in

>Complex I, III, IV and ANT function. What tests were performed?

>

>What kind ofvitamins and other supplements do your girls take.

>

>

> I did not have much problem with my vision until recently, when I went

>on a low carb diet. Prior to this I had suffered from an eye infection, it

>is only now that I have come to know that mito disease sufferers should eat

>three regular meals.

>

>Can you let me know the names of institutes in US, where such genetic

>analysis is done on a research basis,

>

>Have your girls ever tried any alternative medicine

>

>

>

>

>

>Joanne Kocourek (mom to , lies, and )

>visit us at: http://www.caringbridge.org/il/annakris

>

>

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