Guest guest Posted April 6, 2006 Report Share Posted April 6, 2006 I still have a long way to go for my quest for diagnosis, but Dr. Tarnopolsky has ruled out Mito ... he thinks i have FOD (inability to metabolize fats in muscle) ... in many respects i guess similar to mito, but i would be lucky in that it is more localized, and not going to produce the more challenging gut issues etc that so many of you struggle with. Still, is not curable and apparently my muscles are damaged ... however, I have a direction now and some strategies. My goal is to walk some, I am currently unable to walk far at all. I will still lurk here, would be nearly impossible to leave this group cold turkey after leaning on it for so long now .... Thank you all for everything -- *********************************************************** Kelta Vineyard --------------------------------- 7 bucks a month. This is Huge Yahoo! Music Unlimited Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2006 Report Share Posted April 6, 2006 Hi , Please don't leave us too abruptly. THe following article (recently published) referrs to the relationship between FOD's and mitochondrial disease. I honestly believe too few people understand ro respect the interrelationship. 1: Tidsskr Nor Laegeforen. 2006 Mar 9;126(6):756-9. Related Articles, Links [Mitochondrial beta-oxidation defects] [Article in Norwegian] Woldseth B, Rootwelt T. Avdeling for medisinsk biokjemi, Barneklinikken, Rikshospitalet-Radiumhospitalet, 0027 Oslo. berit.woldseth@... BACKGROUND: Mitochondrial beta-oxidation of fatty acids is an important source of energy for the cells, especially during fasting. Since 1973 several inherited defects in beta-oxidation have been described. Defects in mitochondrial beta-oxidation are one of the largest groups of inborn errors of metabolism. MATERIAL AND METHODS: This review article is based on the experience of the authors and on literature studies. The authors' experience is from laboratory diagnostics and clinical experience in the departments of medical biochemistry and peadiatrics at our hospital. RESULTS AND INTERPRETATION: Beta-oxidation defects are potentially fatal disorders. Symptoms are usually seen during fasting, e.g. during childhood infections. Organs which preferably oxidize fatty acids or ketone bodies are especially vulnerable. Often, but not always, the patients have hypoketotic hypoglycaemia. In addition one can see affection of the liver, heart, muscular and nervous systems. The diseases can manifest both in childhood and adulthood and are often less severe in adulthood. The main principles of symptomatic treatment are avoidance of fasting and regular intake of a low-fat, high-carbohydrate diet. The diagnosis can be difficult to establish, especially in asymptomatic phases. Publication Types: Case Reports Review PMID: 16541168 [PubMed - indexed for MEDLINE] Drotos rdrotos@...> wrote: I still have a long way to go for my quest for diagnosis, but Dr. Tarnopolsky has ruled out Mito ... he thinks i have FOD (inability to metabolize fats in muscle) ... in many respects i guess similar to mito, but i would be lucky in that it is more localized, and not going to produce the more challenging gut issues etc that so many of you struggle with. Still, is not curable and apparently my muscles are damaged ... however, I have a direction now and some strategies. My goal is to walk some, I am currently unable to walk far at all. I will still lurk here, would be nearly impossible to leave this group cold turkey after leaning on it for so long now .... Thank you all for everything -- *********************************************************** Kelta Vineyard --------------------------------- 7 bucks a month. This is Huge Yahoo! Music Unlimited Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2006 Report Share Posted April 6, 2006 --- Drotos rdrotos@...> wrote: > I still have a long way to go for my quest for > diagnosis, but Dr. Tarnopolsky has ruled out Mito > ... he thinks i have FOD FODs can cause secondary mito dysfunction. How did they rule out mito? Mom to the two best kids in the world! http://www.caringbridge.org/visit/thomasandkatie __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2006 Report Share Posted April 6, 2006 , I'm sorry to hear that your biopsy/tests hasn't brought you any closer to a real diagnosis. But I too am wondering how they can completely rule out mito? As my neuro likes to remind me, doctors haven't even yet identified all the diseases people like us have If you search back on the archives for " FOD " you will find several discussions in the last year here that indicate links between the two, including the fact that mito can cause secondary FODs issues. Cindy > > > I still have a long way to go for my quest for > > diagnosis, but Dr. Tarnopolsky has ruled out Mito > > ... he thinks i have FOD > > FODs can cause secondary mito dysfunction. How did > they rule out mito? > > > > Mom to the two best kids in the world! > http://www.caringbridge.org/visit/thomasandkatie > > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2006 Report Share Posted April 7, 2006 Oh my, Joanne, what would I or anyone do without this group. Thank you for this article, and yes I have read much about how confused the medical community is on this stuff. Especially the adult forms, obviously the child forms are vital to understand (since so much is preventable if they are screened) .. however, it can as we know be frustrating to be an adult onset patient .. The doc was categorical in his opinion mine was not mito, but perhaps it was a semantics thing ... or, perhaps, he is convinced it is an autosomal recessive. Time will tell ... and, as we know, time for this kind of thing means years. Onward and upward ... thanks again . Hi , Please don't leave us too abruptly. THe following article (recently published) referrs to the relationship between FOD's and mitochondrial disease. I honestly believe too few people understand ro respect the interrelationship. -- *********************************************************** Kelta Vineyard --------------------------------- 7 bucks a month. This is Huge Yahoo! Music Unlimited Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2006 Report Share Posted April 7, 2006 Hi , One of my biggest frustrations when startign down this road around 1996 was the attitude of many physicians who declared that if an individual had a FOD they didn't/couldn't have mito or if an individual had mito thye didn't/couldn't have a FOD. But, from almost everything I have been able to read, just the opposite is true. It is very common for individuals that have a primary FOD to have secondary mitochondrial dysfunction and it is also very common for individuals that have primary mitochondrial disease to have secondary FOD's. It is almost like a " who gets the funding for what wars " . The other BIG consideration is the multitude of inconsistancies in biopsy results from tissue sampkle to tissue sample in affected individuals. Consider my daughters. Between the two of them, they have had a total of 6 skin biopsies and 4 muscle biopsies. Every SAMPLE and every ANALYSIS of those tissues ahve yielded differing results. Some for FOD's (yes, differing FOD's) and some for a variety of differing mitochondrial associated deficiencies. The only thing a majority of the physicians believe is they definitely have a problem related to mitochondrial function and some fatty acid oxidation function. *Then, of course, there are the doubters, who feel they are fine and makign the whole medical picture up because all of the studies differ.* I hope that your specific medical challenges are being appropriately addressed and the actual biochemical " cause " is not clouding the overall picture. Either way, the signs, symptoms and treatment have a fair amount of overlap and I encourage you to remain a part of thsi group. Drotos rdrotos@...> wrote: Oh my, Joanne, what would I or anyone do without this group. Thank you for this article, and yes I have read much about how confused the medical community is on this stuff. Especially the adult forms, obviously the child forms are vital to understand (since so much is preventable if they are screened) .. however, it can as we know be frustrating to be an adult onset patient .. The doc was categorical in his opinion mine was not mito, but perhaps it was a semantics thing ... or, perhaps, he is convinced it is an autosomal recessive. Time will tell ... and, as we know, time for this kind of thing means years. Onward and upward ... thanks again . Hi , Please don't leave us too abruptly. THe following article (recently published) referrs to the relationship between FOD's and mitochondrial disease. I honestly believe too few people understand ro respect the interrelationship. -- *********************************************************** Kelta Vineyard --------------------------------- 7 bucks a month. This is Huge Yahoo! Music Unlimited Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2006 Report Share Posted April 7, 2006 I'm glad you are going to stick around. You are part of this family. I'm glad you are finally getting some answers. laurie > I still have a long way to go for my quest for diagnosis, but Dr. > Tarnopolsky has ruled out Mito ... he thinks i have FOD (inability to > metabolize fats in muscle) ... in many respects i guess similar to mito, > but i would be lucky in that it is more localized, and not going to produce > the more challenging gut issues etc that so many of you struggle with. > > Still, is not curable and apparently my muscles are damaged ... however, > I have a direction now and some strategies. My goal is to walk some, I am > currently unable to walk far at all. I will still lurk here, would be > nearly impossible to leave this group cold turkey after leaning on it for > so long now ... > > Thank you all for everything > > > > > -- > > *********************************************************** > Kelta Vineyard > > --------------------------------- > 7 bucks a month. This is Huge Yahoo! Music Unlimited > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2006 Report Share Posted April 8, 2006 Well, my one data point: I have MERRF, a very rare mito mutation. I also have MSL (Multiple Symmetrical Lipomatosis), EXTREMELY rare. 20% of MSL patients have MERRF, leading one to think that is no coincidence, duh. MSL is still poorly understood, but there is strong suspicion now that there is some fundamental FOD amongst the causes, or at least the triggers. Stands to reason, anyway, since MSL is essentially just fatty acid storage dysfunction in extremis, which must be the result of something. I haven't been tested specifically for FOD (I presume this is done by cellular metabolism analysis of fresh muscle?). Nonetheless, I think it is reasonably likely that I, for one, have both FOD and mito, probably inter-related. Steve D. Re: i don't have mito , I'm sorry to hear that your biopsy/tests hasn't brought you any closer to a real diagnosis. But I too am wondering how they can completely rule out mito? As my neuro likes to remind me, doctors haven't even yet identified all the diseases people like us have If you search back on the archives for " FOD " you will find several discussions in the last year here that indicate links between the two, including the fact that mito can cause secondary FODs issues. Cindy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2006 Report Share Posted April 8, 2006 , Since there are no standards to use when dx mito within the same country, there will most certainly not be agreement between docs in different countries either. There are far from standard tests, so even though Dr. Tarnopolsky doesn't feel you have mito using " his " standards, doesn't mean you don't according to others. Hang in there and please stick around. You sure don't need to leave because one doc doesn't feel you have mito. Hugs, Drotos wrote: >I still have a long way to go for my quest for diagnosis, but Dr. Tarnopolsky has ruled out Mito ... he thinks i have FOD (inability to metabolize fats in muscle) ... in many respects i guess similar to mito, but i would be lucky in that it is more localized, and not going to produce the more challenging gut issues etc that so many of you struggle with. > > Still, is not curable and apparently my muscles are damaged ... however, I have a direction now and some strategies. My goal is to walk some, I am currently unable to walk far at all. I will still lurk here, would be nearly impossible to leave this group cold turkey after leaning on it for so long now .... > > Thank you all for everything > > > > >-- > >*********************************************************** >Kelta Vineyard > >--------------------------------- >7 bucks a month. This is Huge Yahoo! Music Unlimited > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2006 Report Share Posted April 8, 2006 Hi , I just can't resist sticking my 2 cents in! I've decided to stay with this group even though I'm not sure whether I really have mito. For me, the reason is that my symptoms are closer to mito than anything else. Also, my doctor thinks it's so possible that I have mito, she's treating me for it. I'm gradually adding in ingredients of the cocktail and I follow many of the same lifestyle guidelines that people with confirmed mito follow. Whether the dx is right or wrong, I need support and want to feel connected to others who are going through similar experiences. And this group is so understanding and supportive. I realize that your doctor is telling you that you don't have mito and s/he doesn't want to treat you for it, so our situations are slightly different. But for me, the bottom line is, who can we relate to and what kind of support do we want? Even medical mysteries like us deserve support! Best, Shayna > > >I still have a long way to go for my quest for diagnosis, but Dr. Tarnopolsky has ruled out Mito ... he thinks i have FOD (inability to metabolize fats in muscle) ... in many respects i guess similar to mito, but i would be lucky in that it is more localized, and not going to produce the more challenging gut issues etc that so many of you struggle with. > > > > Still, is not curable and apparently my muscles are damaged ... however, I have a direction now and some strategies. My goal is to walk some, I am currently unable to walk far at all. I will still lurk here, would be nearly impossible to leave this group cold turkey after leaning on it for so long now ... > > > > Thank you all for everything > > > > > > > > > >-- > > > >*********************************************************** > >Kelta Vineyard > > > >--------------------------------- > >7 bucks a month. This is Huge Yahoo! Music Unlimited > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2006 Report Share Posted April 8, 2006 Hi , I am glad to see another post that you are deciding to stay. I don't remember whether you stated how mito was actually ruled out. I would be curious to find this out b/c my understanding is there isn't one single way to rule it out. I had a fresh muscle biopsy done in 2003 which was negative. However, I have had multiple bloodwork abnormalities pointing toward mito and several other tests (MRS of my muscle, exercise test, etc) that are also pointing in the mito direction. Most recently, I had two skin biopsies done--one sent to Dr in Toronto and one sent to Dr Enns at Stanford in CA--that have been positive for mito. The one sent to Toronto showed a very high lactate: pyruvate ratio and the one sent to Dr Enns is brand new testing and my results just came back two days ago showing mtDNA defects in Complexes 1 & 4. All this to say that even if something as definitive as a muscle biopsy is negative, it doesn't necessarily mean you don't have mito. Oftentimes getting a diagnosis is like building a case....you have to take clinical history, family history, labwork, muscle biopsy and other factors into account and keep adding them together over the years. Hopefully science will keep improving and those of us without positive muscle biopsies will find other absolute ways of diagnosing mito. Good luck! Malisa In a message dated 4/8/2006 10:59:30 A.M. Eastern Standard Time, dgregori@... writes: I still have a long way to go for my quest for diagnosis, but Dr. Tarnopolsky has ruled out Mito ... he thinks i have FOD (inability to metabolize fats in muscle) ... in many respects i guess similar to mito, but i would be lucky in that it is more localized, and not going to produce the more challenging gut issues etc that so many of you struggle with. > > Still, is not curable and apparently my muscles are damaged ... however, I have a direction now and some strategies. My goal is to walk some, I am currently unable to walk far at all. I will still lurk here, would be nearly impossible to leave this group cold turkey after leaning on it for so long now ... > > Thank you all for everything > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2006 Report Share Posted April 8, 2006 It is an interesting topic - my understanding is that patients with " mild " mitochondrial disease (namely in my mind mild symptoms) can have heterogeneous mitochondrial populations, thus there are " good " and " bad " mitochondria. This is thought to be part of the reason that strenuous exercise helps some mito patients; it may be related to the age of mitochondria. I hate when people say " not curable " as if mito is different from many other diseases in that respect. Treatment of symptoms and resumption of a normal life is close enough for me - YMMV. Even regaining one ability or slowing or stopping the loss of an ability is a victory. Take care, RH > > > > > I still have a long way to go for my quest for > > > diagnosis, but Dr. Tarnopolsky has ruled out Mito > > > ... he thinks i have FOD > > > > FODs can cause secondary mito dysfunction. How did > > they rule out mito? > > > > > > > > Mom to the two best kids in the world! > > http://www.caringbridge.org/visit/thomasandkatie > > > > __________________________________________________ > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2006 Report Share Posted April 8, 2006 >For me, the reason is that my symptoms are closer to mito than > anything else. Also, my doctor thinks it's so possible that I have > mito, she's treating me for it. I was just about to post the same thing! I still belong to a myasthenia gravis group because a lot of the symptoms are similar to mine. Also, the QUEST magazine from the MDA has a lot of great ideas and stories of people with similar problems, but of course most people in the magazine don't have mito. Take care, RH > I'm gradually adding in ingredients of the > cocktail and I follow many of the same lifestyle guidelines that > people with confirmed mito follow. Whether the dx is right or wrong, I > need support and want to feel connected to others who are going > through similar experiences. And this group is so understanding and > supportive. > > I realize that your doctor is telling you that you don't have mito and > s/he doesn't want to treat you for it, so our situations are slightly > different. But for me, the bottom line is, who can we relate to and > what kind of support do we want? Even medical mysteries like us > deserve support! > > Best, > Shayna > > > > > > > >I still have a long way to go for my quest for diagnosis, but Dr. > Tarnopolsky has ruled out Mito ... he thinks i have FOD (inability to > metabolize fats in muscle) ... in many respects i guess similar to > mito, but i would be lucky in that it is more localized, and not going > to produce the more challenging gut issues etc that so many of you > struggle with. > > > > > > Still, is not curable and apparently my muscles are damaged ... > however, I have a direction now and some strategies. My goal is to > walk some, I am currently unable to walk far at all. I will still > lurk here, would be nearly impossible to leave this group cold turkey > after leaning on it for so long now ... > > > > > > Thank you all for everything > > > > > > > > > > > > > > >-- > > > > > >*********************************************************** > > >Kelta Vineyard > > > > > >--------------------------------- > > >7 bucks a month. This is Huge Yahoo! Music Unlimited > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2006 Report Share Posted April 8, 2006 My daughter's muscle biopsy was negitive for mito, but we were told that is only because the piece of muscle taken didn't have the bad mito in it yet, but her other tests, symptoms and family history gave her a mito dx. Malilibear@... wrote: > >Hi , >I am glad to see another post that you are deciding to stay. I don't >remember whether you stated how mito was actually ruled out. I would be curious to >find this out b/c my understanding is there isn't one single way to rule it >out. > >I had a fresh muscle biopsy done in 2003 which was negative. However, I have >had multiple bloodwork abnormalities pointing toward mito and several other >tests (MRS of my muscle, exercise test, etc) that are also pointing in the >mito direction. Most recently, I had two skin biopsies done--one sent to Dr > in Toronto and one sent to Dr Enns at Stanford in CA--that have been >positive for mito. The one sent to Toronto showed a very high lactate: pyruvate >ratio and the one sent to Dr Enns is brand new testing and my results just >came back two days ago showing mtDNA defects in Complexes 1 & 4. > >All this to say that even if something as definitive as a muscle biopsy is >negative, it doesn't necessarily mean you don't have mito. Oftentimes getting a > diagnosis is like building a case....you have to take clinical history, >family history, labwork, muscle biopsy and other factors into account and keep >adding them together over the years. Hopefully science will keep improving and >those of us without positive muscle biopsies will find other absolute ways of >diagnosing mito. > >Good luck! >Malisa > >In a message dated 4/8/2006 10:59:30 A.M. Eastern Standard Time, >dgregori@... writes: > >I still have a long way to go for my quest for diagnosis, but Dr. >Tarnopolsky has ruled out Mito ... he thinks i have FOD (inability to metabolize >fats in muscle) ... in many respects i guess similar to mito, but i would be >lucky in that it is more localized, and not going to produce the more >challenging gut issues etc that so many of you struggle with. > > >> >> Still, is not curable and apparently my muscles are damaged ... however, >> >> >I have a direction now and some strategies. My goal is to walk some, I am >currently unable to walk far at all. I will still lurk here, would be nearly >impossible to leave this group cold turkey after leaning on it for so long >now ... > > >> >> Thank you all for everything >> >> >> >> >> > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2006 Report Share Posted April 8, 2006 Can you tell me how to get the Quest magazine? We know so little about Mito and I have read all the messages here and the transcripts on Monday night trying to gather as much information as possible. If you know of any other ways to get information, please let me know. Thanks. ohgminion rakshasis@...> wrote: >For me, the reason is that my symptoms are closer to mito than > anything else. Also, my doctor thinks it's so possible that I have > mito, she's treating me for it. I was just about to post the same thing! I still belong to a myasthenia gravis group because a lot of the symptoms are similar to mine. Also, the QUEST magazine from the MDA has a lot of great ideas and stories of people with similar problems, but of course most people in the magazine don't have mito. Take care, RH > I'm gradually adding in ingredients of the > cocktail and I follow many of the same lifestyle guidelines that > people with confirmed mito follow. Whether the dx is right or wrong, I > need support and want to feel connected to others who are going > through similar experiences. And this group is so understanding and > supportive. > > I realize that your doctor is telling you that you don't have mito and > s/he doesn't want to treat you for it, so our situations are slightly > different. But for me, the bottom line is, who can we relate to and > what kind of support do we want? Even medical mysteries like us > deserve support! > > Best, > Shayna > > > > > > > >I still have a long way to go for my quest for diagnosis, but Dr. > Tarnopolsky has ruled out Mito ... he thinks i have FOD (inability to > metabolize fats in muscle) ... in many respects i guess similar to > mito, but i would be lucky in that it is more localized, and not going > to produce the more challenging gut issues etc that so many of you > struggle with. > > > > > > Still, is not curable and apparently my muscles are damaged ... > however, I have a direction now and some strategies. My goal is to > walk some, I am currently unable to walk far at all. I will still > lurk here, would be nearly impossible to leave this group cold turkey > after leaning on it for so long now ... > > > > > > Thank you all for everything > > > > > > > > > > > > > > >-- > > > > > >*********************************************************** > > >Kelta Vineyard > > > > > >--------------------------------- > > >7 bucks a month. This is Huge Yahoo! Music Unlimited > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2006 Report Share Posted April 8, 2006 Cathy You can read past copies of Quest at . It is a magazine for all types of muscular dystrophy, but has many articles that apply to us folks and a few specific articles on mito. You can contact your local MDA office to find out about getting the magazine. laurie > Can you tell me how to get the Quest magazine? We know so little about > Mito and I have read all the messages here and the transcripts on Monday > night trying to gather as much information as possible. If you know of any > other ways to get information, please let me know. Thanks. > > > > ohgminion rakshasis@...> wrote: > >For me, the reason is that my symptoms are closer to mito than > > anything else. Also, my doctor thinks it's so possible that I have > > mito, she's treating me for it. > > I was just about to post the same thing! I still belong to a > myasthenia gravis group because a lot of the symptoms are similar to > mine. Also, the QUEST magazine from the MDA has a lot of great ideas > and stories of people with similar problems, but of course most > people in the magazine don't have mito. > > Take care, > RH > > > > > > > > > > I'm gradually adding in ingredients of the > > cocktail and I follow many of the same lifestyle guidelines that > > people with confirmed mito follow. Whether the dx is right or > wrong, I > > need support and want to feel connected to others who are going > > through similar experiences. And this group is so understanding and > > supportive. > > > > I realize that your doctor is telling you that you don't have mito > and > > s/he doesn't want to treat you for it, so our situations are > slightly > > different. But for me, the bottom line is, who can we relate to and > > what kind of support do we want? Even medical mysteries like us > > deserve support! > > > > Best, > > Shayna > > > > > > > > > > > > >I still have a long way to go for my quest for diagnosis, but > Dr. > > Tarnopolsky has ruled out Mito ... he thinks i have FOD (inability > to > > metabolize fats in muscle) ... in many respects i guess similar to > > mito, but i would be lucky in that it is more localized, and not > going > > to produce the more challenging gut issues etc that so many of you > > struggle with. > > > > > > > > Still, is not curable and apparently my muscles are > damaged ... > > however, I have a direction now and some strategies. My goal is to > > walk some, I am currently unable to walk far at all. I will still > > lurk here, would be nearly impossible to leave this group cold > turkey > > after leaning on it for so long now ... > > > > > > > > Thank you all for everything > > > > > > > > > > > > > > > > > > > >-- > > > > > > > > >*********************************************************** > > > >Kelta Vineyard > > > > > > > >--------------------------------- > > > >7 bucks a month. This is Huge Yahoo! Music Unlimited > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 9, 2006 Report Share Posted April 9, 2006 I was under the impression (unsure) that all people with mito had " good " and " bad " mitochondria. If all the mitochondria were bad, a person would be dead, wouldn't they? > > > > > > > I still have a long way to go for my quest for > > > > diagnosis, but Dr. Tarnopolsky has ruled out Mito > > > > ... he thinks i have FOD > > > > > > FODs can cause secondary mito dysfunction. How did > > > they rule out mito? > > > > > > > > > > > > Mom to the two best kids in the world! > > > http://www.caringbridge.org/visit/thomasandkatie > > > > > > __________________________________________________ > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 9, 2006 Report Share Posted April 9, 2006 Shayna You are mostly correct on this. There are some who have all bad mito of a specific kind, but not one that plays an important role in organ system function. My family has a specific gene in complex I mtDNA that is defective in all tested. It was thought that this condition would always been death, but they are finding out that it can exist. It would depend on what that particular gene does. They haven't figured that out for us. If all mitochondria in the body were bad, it would definitely be incompatible with life. laurie > I was under the impression (unsure) that all people with mito had > " good " and " bad " mitochondria. If all the mitochondria were bad, a > person would be dead, wouldn't they? > > > > > > > > > > > > > > I still have a long way to go for my quest for > > > > > diagnosis, but Dr. Tarnopolsky has ruled out Mito > > > > > ... he thinks i have FOD > > > > > > > > FODs can cause secondary mito dysfunction. How did > > > > they rule out mito? > > > > > > > > > > > > > > > > Mom to the two best kids in the world! > > > > http://www.caringbridge.org/visit/thomasandkatie > > > > > > > > __________________________________________________ > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 9, 2006 Report Share Posted April 9, 2006 The higher the concentration of bad mitochondria in a given area of the body, the more problems that person will have with that organ system lets say. The % of good to bad mitochondria is not the same throughout the body. shaynapearl wrote: >I was under the impression (unsure) that all people with mito had > " good " and " bad " mitochondria. If all the mitochondria were bad, a >person would be dead, wouldn't they? > > > > >>>> >>>> >>>> >>>>>I still have a long way to go for my quest for >>>>>diagnosis, but Dr. Tarnopolsky has ruled out Mito >>>>>... he thinks i have FOD >>>>> >>>>> >>>>FODs can cause secondary mito dysfunction. How did >>>>they rule out mito? >>>> >>>> >>>> >>>>Mom to the two best kids in the world! >>>>http://www.caringbridge.org/visit/thomasandkatie >>>> >>>>__________________________________________________ >>>> Quote Link to comment Share on other sites More sharing options...
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