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Hi Shayna,

There was an abstract at the UMDF conference written by Dr Boles regarding

the association of RSD/CRPS to maternally inherited mitochondrial disease.

Apparently he has quite a few patients who have both. It was a pretty

interesting abstract. I'm not sure if it's published yet.

Malisa

In a message dated 6/30/2006 12:45:26 P.M. Eastern Standard Time,

happyclam8@... writes:

Dear Enrique,

I noticed that some of the mito folks in your family have Complex

Regional Pain Syndrome. Would you mind telling me what type of pain

they have? Is it neurological (burning, electrical type pain, etc.) or

muscular (cramping, aching, soreness, etc.)? Is there any treatment

that's helped reduce their pain?

Decades ago (before I knew about mito), I was diagnosed with Reflex

Sympathetic Dystrophy (RSD). Years later, many doctors started saying

that Complex Regional Pain Syndrome was a better name for everyone

with RSD. I haven't heard anyone else with mito say they have or have

had RSD. Do you know if the pain syndrome your family members have is

what used to be called RSD? I would be very interested--what used to

they have found anything that helps!

Best wishes,

Shayna

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Hi Shayna,

This is the mom to the group with Complex Regional Pain Syndrome,

Enrique doesn't do a lot of the medical stuff for our family usually. I sent

the

post so I thought it would be ok to answer for him. The type of pain they

get most often is a burning nerve like pain. It can be very intense, they do

have the muscle pain as well where they just ache for no reason at all

really, but it is my understanding that the burning nerve like pain is more the

CRP

from Dr. Boles.

had to use narcotics at one point to control his pain. We went

through pain management at Children's La to try and help him. It was awful

pain that he had at that point from the lipomas being removed, he could hardly

stand the pain. It is very hard to watch them be in such pain when it flairs

up.

Kira will get hot burning pain and her arms will swell up and will be

really red and hot to the touch. We use the Ibuprophen 600-800 mg and sleep

for her. Sometimes heat/cold to it will relieve the pain but not always.

As for Krisalynn, hers wasn't kicked off until she compound broke her arm.

It swelled really bad in the cast and the burning pain was almost intolerable

for her. The doctor from Loma accused her of being a baby and over

reacting, and told me it was just a compound break and to not baby her, until

I

could get him to talk to Dr Boles and have him explain to this idiot what

was going on.( I am not angry at this doctor now am I LOL) We iced her cast

with a continuous ice machine that she kept on for 8 hours at a time and gave

her anti swelling medication along with codeine., split her cast to allow for

the swelling and of course elevated it. It flairs up every once in awhile for

no apparent reason now on and off and for the most part icing it and high

amounts of ibuprohen seem to help her. We have not found any magical

treatment per say for it although Dr. Boles is trying. My kids all take

amitriptaline as well which helps with the dysautonomia, which could in turn

help with

the CRP, but I am not totally sure on that.

My family was in Dr. Bole's study which he presented at the symposium. I

have not seen what was published as of yet but hope to. I don't know if he

has it out as a full publication or not, but I will ask him and let you know.

If we can answer any more questions just let me know. It is a crazy thing

to deal with, I can tell you that!

O

Mom to Kira almost 16 yrs- Mitochondrial Myopathy- Maternally Inherited

Dysautonomia-Cyclic Vomiter-Complex Regional Pain Syndrome- ASD/VSD mitral valve

repair 2000-G tube 1999

13yrs- Mitochondrial Myopathy-Maternally Inherited Dysautonomia-

Complex Regional Pain Syndrome- Lipoma removals 2004/2005 upper neck area.

Krisalynn 10 yrs- Mitochondrial Myopathy Maternally Inherited Dysautonomia-

Complex Regional pain Syndrome set off by compound break of arm

2005-hypertonia of the bladder

Enrique- The dad of the group!

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Dear Enrique,

I noticed that some of the mito folks in your family have Complex

Regional Pain Syndrome. Would you mind telling me what type of pain

they have? Is it neurological (burning, electrical type pain, etc.) or

muscular (cramping, aching, soreness, etc.)? Is there any treatment

that's helped reduce their pain?

Decades ago (before I knew about mito), I was diagnosed with Reflex

Sympathetic Dystrophy (RSD). Years later, many doctors started saying

that Complex Regional Pain Syndrome was a better name for everyone

with RSD. I haven't heard anyone else with mito say they have or have

had RSD. Do you know if the pain syndrome your family members have is

what used to be called RSD? I would be very interested--especially if

they have found anything that helps!

Best wishes,

Shayna

>

> Hi ,

>

> Both My son and daughter have been through treadmill stress tests.

With

> his legs fatigued very quickly and they had to stop. Kira

however was

> able to go long enough for them to see what they needed to see prior

to her

> heart surgery. With they put him in a non weight bearing

situation, it

> was like a treadmill under water and he walked that for them and

they got what

> they needed from that. The conventional one was out for him.

Good luck

> with your test.

> O

>

> Mom to Kira almost 16 yrs- Mitochondrial Myopathy- Maternally

Inherited

> Dysautonomia-Cyclic Vomiter-Complex Regional Pain Syndrome- ASD/VSD

mitral valve

> repair 2000-G tube 1999

> 13yrs- Mitochondrial Myopathy-Maternally Inherited Myopathy-

Complex

> Regional Pain Syndrome- Lipoma removals 2004/2005 upper neck area.

> Krisalynn 10 yrs- Mitochondrial Myopathy Maternally Inherited

Dysautonomia-

> Complex Regiaonl pain Syndrome set off by compound break of arm

> 2005-hypertonia of the bladder

>

> Enrique- The dad of the group!

>

>

>

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