MITO AND PROBLEMS OF THE HEART?

[Guest guest]

I think those are all excellent points. I also think this needs to be

checked carefully and immediately. I also wondered about blood pressure.

Various meds may interact and react differently with all of us. Bring a list of

any med's you are taking Randall even over the counter and things like

aspirin. Good luck! Vivian

[Guest guest]

Randall,

I too have the cholesterol issues, but was told that due to having Mito I

should not take Stanton based drugs. I believe it is due to the fact that

Stanton drugs block the Mito cells from working properly and if you are already

compromised you can't afford to block the working ones. Maybe someone else

has a little more info on this. I know we avoid them with my son as well due

to his Mito. You might want to ask on this one from the Nuro or the

cardiologist.

O

Mom to Kira almost 16 yrs- Mitochondrial Myopathy- Maternally Inherited

Dysautonomia-Cyclic Vomiter-Complex Regional Pain Syndrome- ASD/VSD mitral valve

repair 2000-G tube 1999

13yrs- Mitochondrial Myopathy-Maternally Inherited Dysautonomia-

Complex Regional Pain Syndrome- Lipoma removals 2004/2005 upper neck area.

Krisalynn 10 yrs- Mitochondrial Myopathy Maternally Inherited Dysautonomia-

Complex Regiaonl pain Syndrome set off by compound break of arm

2005-hypertonia of the bladder

Enrique- The dad of the group!

[Guest guest]

I've noticed people mentioning heart-related issues here. Up until now, assumed

I didn't have any or didn't make the possible connection. For the past 4-5 days

I've been having some intermittent, if mild, discomfort in chest and sometimes a

weird sensation in head that is hard to describe. It is sort of like

light-headedness but not exactly. Exercising seems to bring on these symptoms

but they also seem to occur when at rest. I had a similar " flare up " of these

kind of symptoms about 4 - 5 months ago that lasted for a few weeks, then seemed

to get better. Went to the ER a few times and to Cardiologist. Had various

tests - regular echo, CT coronary angiography and, recently, pulmonary testing

that involved treadmill testing - that did not show anything. In fact CT

coronary angiography surprisingly showed no coronary blockages. Have had

Thallium stress tests - most recent about a year ago - that were considered

normal. Cardiologist said symptoms most likely due to Costochondritis of

ribcage, which he had dx years before and which I definitely have (soreness of

chest muscles, rib area). I'm pretty sure that some of the symptoms are related

to the Costochondritis, but not sure they all are. Aside from that, just mild,

intermittent mitral valve prolapse (not always seen on echo) and high

cholesterol, currently controlled by statins.

Wondering if any of these symptoms could be related to Mito (which I still have

doubts about neuros dx). Are there specific things the Cardiologist would need

to look for to find mito-related cardiac problems? I ask this because the

Cardiologist didn't know of the Mito dx when he did work up (and past work ups).

I do have some bradycardia (resting heart rate is usually around 55 - 60, though

once in awhile in 40's) which seems to run in mother's side and father has

atrial fibrillation, which 1 or 2 of his siblings apparently also have. I

exercise pretty regularly and am in pretty good cardiovascular shape for someone

in their early 50s. Is bradycardia or mitral valve prolapse related to Mito?

Think I may have mentioned it before, but apparently both mitral valve prolapse

AND some myopathies are often associated with a very high-arched palate. Is

this common in Mito folks? If so, might point to connection between Mito and

Mitral Valve Prolapse (MVP), and to connective tissue disorder, which MVP might

be related to.

Wondering if I should call the Cardiologist and specifically mention the Mito

diagnosis in case there are things he should test or look for that he might not

otherwise have done. For example, have never had a stress echo and wonder if I

would need this to rule out Mito-related cardiac problems, despite having had

regular echos, thallium stress tests (even halter monitors many years ago), etc.

I want and need to exercise for physical and mental health) but am again a bit

scared to do much while having symptoms. Was on treadmill yesterday and head

symptoms seemed to start up when got up to a fairly high intensity.

Would appreciate any thoughts. The neuro who says I have Mito didn't mention

anything about cardiac complications. Does CoQ10 help with the Mito cardiac

problems? I know, from my past experience, that anxiety about possible cardiac

symptoms can exacerbate symptoms, if not create some of them, so don't want to

simply give in to this anxiety and avoid exercise, but also don't want to do

something foolish either. Also realize, from past experience, that anxiety or

depression about other things can bring on some apparent cardiac-related

symptoms in the first place.

Hope everyone here has a good 4th weekend.

Randall

[Guest guest]

Hi,

I'm not a doc, so keep that in mind. I have had various mild heart

issues that I have been lucky enough to seem to have been resolved by

upping my CoQ10 level. I had left ventricular diastolic dysfunction

that is no longer present, per the same cardiologist that dx'ed it in

the first place. Before that I had tacicardia (sp) episodes, especially

at night at rest, CoQ10 increase took care of that too. The discomfort

in your chest should be checked out. I would mention the mito as there

might be things that they would only look for cardiac wise in a much

older person that they might look at now if they knew about the mito.

THAT, is if the doc knows anything about mito. Basically, anything

cardiac can happen more quickly with mito if the heart happens to be one

of the muscles with a lot of bad mito % wise. Don't assume it is the

ribcage issue like before. The weird sensation in the head sound like

it might be what I experienced when my blood pressure was up. I have

determined two things that raise my blood pressure, taking Naprosyn

(other NSAIDs don't seem to be an issue) and of all weird things,

creatine.

Yes, CoQ10 is known to help with some cardiac issues from what I have

read and from my own cardiologist. He was thrilled to find out I took

CoQ10 and Fish Oil. Are you aware that Statins deplete even non mito

folks levels of CoQ10? That is another reason you might want to ask

your doc about upping it.

I would get things checked out. Let us know how you are doing and if

you go to the doc what they say.

I hope you have a wonderful holiday too.

Randall Bosin wrote:

> I've noticed people mentioning heart-related issues here. Up until

> now, assumed I didn't have any or didn't make the possible connection.

> For the past 4-5 days I've been having some intermittent, if mild,

> discomfort in chest and sometimes a weird sensation in head that is

> hard to describe. It is sort of like light-headedness but not exactly.

> Exercising seems to bring on these symptoms but they also seem to

> occur when at rest. I had a similar " flare up " of these kind of

> symptoms about 4 - 5 months ago that lasted for a few weeks, then

> seemed to get better. Went to the ER a few times and to Cardiologist.

> Had various tests - regular echo, CT coronary angiography and,

> recently, pulmonary testing that involved treadmill testing - that did

> not show anything. In fact CT coronary angiography surprisingly showed

> no coronary blockages. Have had Thallium stress tests - most recent

> about a year ago - that were considered normal. Cardiologist said

> symptoms most likely due to Costochonditis of ribcage, which he had dx

> years before and which I definitely have (soreness of chest muscles,

> rib area). I'm pretty sure that some of the symptoms are related to

> the Costochondritis, but not sure they all are. Aside from that, just

> mild, intermittent mitral valve prolapse (not always seen on echo) and

> high cholesterol, currently controlled by statins.

>

> Wondering if any of these symptoms could be related to Mito (which I

> still have doubts about neuros dx). Are there specific things the

> Cardiologist would need to look for to find mito-related cardiac

> problems? I ask this because the Cardiologist didn't know of the Mito

> dx when he did work up (and past work ups). I do have some bradycardia

> (resting heart rate is usually around 55 - 60, though once in awhile

> in 40's) which seems to run in mother's side and father has atrial

> fibrillation, which 1 or 2 of his siblings apparently also have. I

> exercise pretty regularly and am in pretty good cardiovascular shape

> for someone in their early 50s. Is bradycardia or mitral valve

> prolapse related to Mito? Think I may have mentioned it before, but

> apparently both mitral valve prolapse AND some myopathies are often

> associated with a very high-arched palate. Is this common in Mito

> folks? If so, might point to connection between Mito and Mitral Valve

> Prolapse (MVP), and to connective tissue disorder, which MVP mightbe

> related to.

>

> Wondering if I should call the Cardiologist and specifically mention

> the Mito diagnosis in case there are things he should test or look for

> that he might not otherwise have done. For example, have never had a

> stress echo and wonder if I would need this to rule out Mito-related

> cardiac problems, despite having had regular echos, thallium stress

> tests (even halter monitors many years ago), etc. I want and need to

> exercise for physical and mental health) but am again a bit scared to

> do much while having symptoms. Was on treadmill yesterday and head

> symptoms seemed to start up when got up to a fairly high intensity.

>

> Would appreciate any thoughts. The neuro who says I have Mito didn't

> mention anything about cardiac complications. Does CoQ10 help with the

> Mito cardiac problems? I know, from my past experience, that anxiety

> about possible cardiac symptoms can exacerbate symptoms, if not create

> some of them, so don't want to simply give in to this anxiety and

> avoid exercise, but also don't want to do something foolish either.

> Also realize, from past experience, that anxiety or depression about

> other things can bring on some apparent cardiac-related symptoms in

> the first place.

>

> Hope everyone here has a good 4th weekend.

>

> Randall

>

>