RE: Re: increased lipids on muscle biopsy

[Guest guest]

Hyperlipidemia is defined as an excess of lipids in blood. That's a

different issue than excess lipid storage in a muscle biopsy. Many people

in the general population have some form of hyperlipidemia, while excess

lipid storage in a muscle biopsy is uncommon and usually associated with

either a primary inborn error in fat metabolism or a secondary biochemical

disturbance in fat metabolism due to another inborn metabolic

disorder---such as a mitochondrial disease. I do happen to have a lipid

storage disorder--that's what CPT deficiency is. A small percentage of

people with CPT have elevated serum cholesterol or triglycerides, but the

percentage is no larger than in the general population. It's not known

whether there is any connection.

Barbara

> Re: increased lipids on muscle biopsy

>

> I personally haven't ever had increased lipids ( hyperlipidemia )

> but here is some info I found.

>

> What causes hyperlipidemia?

>

> Most hyperlipidemia is caused by lifestyle habits or treatable

> medical conditions. Lifestyle contributors include obesity, not

> exercising, and smoking. Conditions that cause hyperlipidemia

> include diabetes, kidney disease, pregnancy, and an underactive

> thyroid gland.

>

> You can also inherit hyperlipidemia. The cause may be genetic if you

> have a normal body weight and other members of your family have

> hyperlipidemia.

>

> You have a greater chance of developing hyperlipidemia if you are a

> man older than age 45 or a woman older than age 55. If a close

> relative had early heart disease (father or brother affected before

> age 55, mother or sister affected before age 65), you also have an

> increased risk.

>

> bug

[Guest guest]

Barbara

Thanks for the info. That is what I thought, but didn't want to say so

without first checking and now I won't have to.

Laurie

> Hyperlipidemia is defined as an excess of lipids in blood. That's a

> different issue than excess lipid storage in a muscle biopsy. Many people

> in the general population have some form of hyperlipidemia, while excess

> lipid storage in a muscle biopsy is uncommon and usually associated with

> either a primary inborn error in fat metabolism or a secondary biochemical

> disturbance in fat metabolism due to another inborn metabolic

> disorder---such as a mitochondrial disease. I do happen to have a lipid

> storage disorder--that's what CPT deficiency is. A small percentage of

> people with CPT have elevated serum cholesterol or triglycerides, but the

> percentage is no larger than in the general population. It's not known

> whether there is any connection.

>

> Barbara

>

>

> > Re: increased lipids on muscle biopsy

> >

> > I personally haven't ever had increased lipids ( hyperlipidemia )

> > but here is some info I found.

> >

> > What causes hyperlipidemia?

> >

> > Most hyperlipidemia is caused by lifestyle habits or treatable

> > medical conditions. Lifestyle contributors include obesity, not

> > exercising, and smoking. Conditions that cause hyperlipidemia

> > include diabetes, kidney disease, pregnancy, and an underactive

> > thyroid gland.

> >

> > You can also inherit hyperlipidemia. The cause may be genetic if you

> > have a normal body weight and other members of your family have

> > hyperlipidemia.

> >

> > You have a greater chance of developing hyperlipidemia if you are a

> > man older than age 45 or a woman older than age 55. If a close

> > relative had early heart disease (father or brother affected before

> > age 55, mother or sister affected before age 65), you also have an

> > increased risk.

> >

> > bug

>

>

>

>

>

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