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Re: Digest Number 4051

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My daughter was taking 30 mg of Prostigmin (neostigmin) every 4 hours, and

it helped her weakness. When she had her sternotomy (open-heart) the

surgeon also took her Thymus gland. The pathology report stated that the

tissue had lymphoid hyperplasia and that thymic lymphoid hyperplasia is

seen in association with Myasthenia Gravis. While she is here at Mass General

(she's been here for over 3 weeks now) we hope to ask the neurologist if

there has been any correlations drawn between sero-negative Myasthenia or

Myasthenia syndrome and Mito. Since her thymectomy, her weakness has

improved, and she is currently not taking the prostigmine. We'll see what

happens after her colectomy (either this Friday, or sometime next week) if she

needs it again. Other stimulants like albuterol (used for breathing treatments)

had to be stopped because they sent her into atrial fibrillation.

-Lyn (Bonnie's Mummy)

www.caringbridge.org/az/bonniemarie

Date: Sat, 04 Feb 2006 22:14:59 -0000

Subject: new here---first question

I am new here and have lots of questions but hope to answer most of

them by reading. How glad I am to find this forum! Not much

available online for adults with mito I am finding. I have double

vision about half of the time so sometimes reading is tough but will

try. I, like others as I have read so far, was diagnosed with MS

first and now it is looking like mitochondrial disease. I haven't

had a muscle biopsy yet but am taking the supplements and they seem

to be helping.

I am wondering if any of you are on any stimulants? Since the MS

diagnosis I have been taking adderral and provigil, two stimulants.

If I don't take them I will just sleep all day. When I used to read

about MS it was very common to be on these meds, but I haven't read

any stories of mito people on them. I also take Mestinon for

strength and topomax for my headaches.

If you have tried or or taking stimulants please tell me what and how

they work for you? Sometimes I wonder if they cause me more problems

then they are worth and now that I have read about heart problems

with mito, I am concerned. However, I don't know what I would do

without them. Like I said earlier, I would just sleep all day.

Thank you in advance.

Marie Codier

Early Childhood Music & Movement Specialist

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