mito caused by substances?

[Guest guest]

RH, and others...

I am interested in your remark, excerpted below, about a drug that causes

mito damage.

1) Is there perhaps a distinction I'm missing, e.g. between mito DAMAGE, and

the mito DISEASE/DISORDER we have, on this list? Do you mean that

erythromycin COULD be the SOLE cause of mito? Not so much in yourself, but

in ANYONE?

2) I'm not sure but I THINK this is the first I've heard (on THIS list,

anyway) about a SUBSTANCE causing mito. Seems we either have a known genetic

connection (or it's obvious, by inflicting multiple family members), or are

generally searching for same. Could you please list any other substances

known or thought to be in this category? I know of AARTs (such as AZT, for

HIV/AIDS), some environmental toxins such as mercury and certain pesticides,

and perhaps others (I suspected Depakote/valproate, in my case, until MERRF

was found in my blood, but I still wonder if it somehow contributed). I'm

very intrigued.

3) Do you have pointer(s) for more info?

Steve D.

> Date: Tue, 01 Nov 2005 18:27:52 -0000

>

> Subject: Re: New to the group....again---MRI SPECTROSKY... RESULTS ARE IN

>

> [...]

> I was also called a hypochondriac by my brothers, I was sick for six

> or more weeks per year from 12 to 18. That's when I took A LOT of

> erythromycin, which now we know is one drug that can cause mito

> damage.

>

> [...]

>

> Take care,

> RH