Re: nDNA and mtDNA defects question

[Guest guest]

http://hmg.oxfordjournals.org/cgi/content/full/10/20/2277

Here's a quote about which OxPhos subunits are mtDNA encoded and which are

nDNA encoded. " The subunits of the five enzyme complexes are encoded in both

the nuclear and mitochondrial genomes; of the 82 structural subunits, 13 are

encoded in mtDNA. "

http://www.neuro.wustl.edu/neuromuscular/pathol/diagrams/mito.htm

Scroll down to the OxPhos composition table for more specifics on the

division of subunits in each complex. For example, complex I has 39 nDNA

subunits and 7 mt DNA subunits.

I used to have a site bookmarked that listed the names of every subunit for

complexes I-V along with their code status, but can't seem to find that at

the moment.

Barbara

> my " mtDNA " " blueprints " seem to be okay, but my " nDNA " blueprints for

> the mitochondrial proteins are messed up. They code for different

> things in the mitochondria (does anyone have a brief summary as to

> what they do code for?).

>

> Take care,

> RH

[Guest guest]

Barbara! How lovely to see your signature on a post. I hope the fact

that you were able to post indicates some improvement but I won't

pressure you to give an update before you are ready. Of course you

know we are all rooting for you.

Happy to " see " you,

Shayna

>

> http://hmg.oxfordjournals.org/cgi/content/full/10/20/2277

> Here's a quote about which OxPhos subunits are mtDNA encoded and

which are

> nDNA encoded. " The subunits of the five enzyme complexes are encoded

in both

> the nuclear and mitochondrial genomes; of the 82 structural

subunits, 13 are

> encoded in mtDNA. "

>

> http://www.neuro.wustl.edu/neuromuscular/pathol/diagrams/mito.htm

> Scroll down to the OxPhos composition table for more specifics on the

> division of subunits in each complex. For example, complex I has 39 nDNA

> subunits and 7 mt DNA subunits.

>

> I used to have a site bookmarked that listed the names of every

subunit for

> complexes I-V along with their code status, but can't seem to find

that at

> the moment.

>

> Barbara

>

>

> > my " mtDNA " " blueprints " seem to be okay, but my " nDNA " blueprints for

> > the mitochondrial proteins are messed up. They code for different

> > things in the mitochondria (does anyone have a brief summary as to

> > what they do code for?).

> >

> > Take care,

> > RH

>