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Abnormal glucose tolerance in cystic fibrosis: Why should patients be

screened? -- Journal of Pediatrics

http://www.pulmonologylinx.com/thearts.cfm?artid=519589 & specid=14

Conclusion: Whereas the optimal treatment of their insulin deficient

state is debatable and awaits the completion of ongoing studies, these

high-risk patients warrant close observation and aggressive treatment of

their pulmonary status by the CF team...

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Glucose intolerance in children with cystic fibrosis -- Journal of

Pediatrics

http://www.pulmonologylinx.com/thearts.cfm?artid=519596 & specid=14

Conclusion: Screening of pancreatic-insufficient, adolescent patients

with CF identified more with abnormal oral glucose tolerance than was

suspected clinically and is recommended as a routine practice. HbA1C was

not useful in screening for CF-related glucose intolerance...

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Health values of adolescents with cystic fibrosis -- Journal of

Pediatrics

http://www.pulmonologylinx.com/thearts.cfm?artid=519597 & specid=14

Conclusion: Direct utility assessment in adolescents with CF is

feasible. Their TTO and SG utilities are generally high, indicating that

they are willing to trade very little of their life expectancy or take

more than a small risk of death to obtain perfect health. Their

self-rated health perceptions are related to their health values, but,

as in adult populations, only moderately so, indicating that health

values are highly individualistic. Therefore, health values should be

ascertained directly from adolescents...

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Molecular Species Compositions of Lung and Pancreas Phospholipids in the

cftrtm1HGU/tm1HGU Cystic Fibrosis Mouse -- Pediatric Research

http://www.pulmonologylinx.com/thearts.cfm?artid=519736 & specid=14

Conclusion: These results demonstrate the variability of membrane

phospholipid compositions in different mouse models of CF and suggest

that in cftrtm1HGU/tm1HGU mice, the apparent deficiency was of 20:4n-6-

rather than of 22:6n-3–containing phospholipid species. They highlight

a need for detailed phospholipid molecular species analysis of cells

expressing mutant CFTR from children with CF before the therapeutic

effects of administering high doses of 22:6n-3–containing oils to

children with CF can be fully evaluated...

Becki

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Pediatric Interstitial Lung Disease Society

http://groups.yahoo.com/group/InterstitialLung_Kids/

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