Guest guest Posted February 11, 2003 Report Share Posted February 11, 2003 J Appl Physiol 94: 576-582, 2003. First published October 11, 2002; 10.1152/japplphysiol.00564.2002 Vol. 94, Issue 2, 576-582, February 2003 Magnitude estimation of inspiratory resistive loads by double-lung transplant recipients Weiying Zhao, A. , and W. Davenport Department of Physical Therapy and Physiological Sciences, University of Florida, Gainesville, Florida 32610 The purpose of this study was to investigate the role of afferent input from the lung and lower airways in magnitude estimation of inspiratory resistive loads ®. To assess the role of lung vagal afferents in respiratory sensation, sensations related to inspiratory R, reflected by subjects' percentage of handgrip responses (HG%), were compared between double-lung transplant (DLT) recipients with normal lung function and healthy control (Nor) subjects. Perceptual sensitivity to the external load was measured as the slope of HG% as a function of peak mouth pressure (Pm), and the slope of HG% as a function of R, after a log-log transformation. The results showed that the DLT group had a similar HG% response, as well as the slopes of log HG%-log Pm and log HG%-log R, compared with the Nor group. Furthermore, the ventilatory responses to external loads were also similar between the two groups. These results suggest that lung vagal afferents do not play a significant role in magnitude estimation of inspiratory resistive loads in humans. respiratory sensation; psychophysics; inspiratory load; load compensation Becki YOUR FAVORITE LilGooberGirl YOUNGLUNG EMAIL SUPPORT LIST www.topica.com/lists/younglung Pediatric Interstitial Lung Disease Society http://groups.yahoo.com/group/InterstitialLung_Kids/ Quote Link to comment Share on other sites More sharing options...
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