Re: preventing angiogenesis

[Guest guest]

> Did you get to read that entire classification article?

Yes I did, Matija. I wish we could post it, because the full article

is much better than the summaries.

> About his bias in viewing rosacea as a vascular disorder, what do

> you think the primary etiology of it is? I'm not saying that to

> refute your statement, but am curious about your ideas.

I don't know what the primary etiology is. Both primary vascular and

primary immune-mediated theories of rosacea have strengths and

limitations.

It's probably multi-factorial, possibly with a genetic

predisposition. These days, I'm wondering whether early exposure to

the sun sensitizes (something) that later results in pre-rosacea or

rosacea. I don't know. I'm not committing myself at the moment. The

more I learn about rosacea, the less I know. ( " I was so much older

then, I'm younger than that now. " <g>)

My Back Pages Lazoff

Marjorie Lazoff, MD

[Guest guest]

> Did you get to read that entire classification article?

Yes I did, Matija. I wish we could post it, because the full article

is much better than the summaries.

> About his bias in viewing rosacea as a vascular disorder, what do

> you think the primary etiology of it is? I'm not saying that to

> refute your statement, but am curious about your ideas.

I don't know what the primary etiology is. Both primary vascular and

primary immune-mediated theories of rosacea have strengths and

limitations.

It's probably multi-factorial, possibly with a genetic

predisposition. These days, I'm wondering whether early exposure to

the sun sensitizes (something) that later results in pre-rosacea or

rosacea. I don't know. I'm not committing myself at the moment. The

more I learn about rosacea, the less I know. ( " I was so much older

then, I'm younger than that now. " <g>)

My Back Pages Lazoff

Marjorie Lazoff, MD

[Guest guest]

> Did you get to read that entire classification article?

Yes I did, Matija. I wish we could post it, because the full article

is much better than the summaries.

> About his bias in viewing rosacea as a vascular disorder, what do

> you think the primary etiology of it is? I'm not saying that to

> refute your statement, but am curious about your ideas.

I don't know what the primary etiology is. Both primary vascular and

primary immune-mediated theories of rosacea have strengths and

limitations.

It's probably multi-factorial, possibly with a genetic

predisposition. These days, I'm wondering whether early exposure to

the sun sensitizes (something) that later results in pre-rosacea or

rosacea. I don't know. I'm not committing myself at the moment. The

more I learn about rosacea, the less I know. ( " I was so much older

then, I'm younger than that now. " <g>)

My Back Pages Lazoff

Marjorie Lazoff, MD

[Guest guest]

> Did you get to read that entire classification article?

Yes I did, Matija. I wish we could post it, because the full article

is much better than the summaries.

> About his bias in viewing rosacea as a vascular disorder, what do

> you think the primary etiology of it is? I'm not saying that to

> refute your statement, but am curious about your ideas.

I don't know what the primary etiology is. Both primary vascular and

primary immune-mediated theories of rosacea have strengths and

limitations.

It's probably multi-factorial, possibly with a genetic

predisposition. These days, I'm wondering whether early exposure to

the sun sensitizes (something) that later results in pre-rosacea or

rosacea. I don't know. I'm not committing myself at the moment. The

more I learn about rosacea, the less I know. ( " I was so much older

then, I'm younger than that now. " <g>)

My Back Pages Lazoff

Marjorie Lazoff, MD

[Guest guest]

Can somebody please give me a basic understanding of the theory that

explains cea as primarily an immune-mediated disorder? I have a very

low WBC count. In addition to this, I have dermatographism and other stuff

that I was told seems to be coming from the fact that my immune system is

depressed. In my case, this has most likely been caused by long-term

minocycline use. I'm wondering what would happen if I stopped taking it for

a long period of time. I've had problems stopping in the past because

things get so much worse after discontinuing, but perhaps, if I stick with

trying to quit for several months, my skin will be better off in the long

run?

(P.S. Not sure anyone is interested, but personally, it seems to me that

cea probably has tons of different causes. Immune-mediated for some,

primarily vascular in nature for others, digestion-related for others,

primarily an inflammatory disease for others etc.. Hence no one medication

will work for everyone, and not everyone will have the same triggers)

[Guest guest]

Can somebody please give me a basic understanding of the theory that

explains cea as primarily an immune-mediated disorder? I have a very

low WBC count. In addition to this, I have dermatographism and other stuff

that I was told seems to be coming from the fact that my immune system is

depressed. In my case, this has most likely been caused by long-term

minocycline use. I'm wondering what would happen if I stopped taking it for

a long period of time. I've had problems stopping in the past because

things get so much worse after discontinuing, but perhaps, if I stick with

trying to quit for several months, my skin will be better off in the long

run?

(P.S. Not sure anyone is interested, but personally, it seems to me that

cea probably has tons of different causes. Immune-mediated for some,

primarily vascular in nature for others, digestion-related for others,

primarily an inflammatory disease for others etc.. Hence no one medication

will work for everyone, and not everyone will have the same triggers)

[Guest guest]

Can somebody please give me a basic understanding of the theory that

explains cea as primarily an immune-mediated disorder? I have a very

low WBC count. In addition to this, I have dermatographism and other stuff

that I was told seems to be coming from the fact that my immune system is

depressed. In my case, this has most likely been caused by long-term

minocycline use. I'm wondering what would happen if I stopped taking it for

a long period of time. I've had problems stopping in the past because

things get so much worse after discontinuing, but perhaps, if I stick with

trying to quit for several months, my skin will be better off in the long

run?

(P.S. Not sure anyone is interested, but personally, it seems to me that

cea probably has tons of different causes. Immune-mediated for some,

primarily vascular in nature for others, digestion-related for others,

primarily an inflammatory disease for others etc.. Hence no one medication

will work for everyone, and not everyone will have the same triggers)

[Guest guest]

Can somebody please give me a basic understanding of the theory that

explains cea as primarily an immune-mediated disorder? I have a very

low WBC count. In addition to this, I have dermatographism and other stuff

that I was told seems to be coming from the fact that my immune system is

depressed. In my case, this has most likely been caused by long-term

minocycline use. I'm wondering what would happen if I stopped taking it for

a long period of time. I've had problems stopping in the past because

things get so much worse after discontinuing, but perhaps, if I stick with

trying to quit for several months, my skin will be better off in the long

run?

(P.S. Not sure anyone is interested, but personally, it seems to me that

cea probably has tons of different causes. Immune-mediated for some,

primarily vascular in nature for others, digestion-related for others,

primarily an inflammatory disease for others etc.. Hence no one medication

will work for everyone, and not everyone will have the same triggers)