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Helen, an alternative is that aggressive exfoliative treatment causes

an irritative contact dermatitis, and interruption of the epithelial

protective barrier perpetuates the underlying dermatitis. Not

everything that is acneiform is rosacea, even in rosaceans.

So the key may not be easy flushing/blushing, but skin sensitivity

(that is a frequent rosacean feature from pre-condition onwards, but

also affects non-rosaceans) upon which aggressive treatment causes an

inflammatory reaction more common in rosaceans but unrelated to

rosacea itself. I don't know.

To gain more information, I performed a quick Medline search on

various related terms and came up with:

-=-=-=

Dermatol Surg 1998 Mar;24(3):337-41

The etiology of prolonged erythema after chemical peel.

Maloney BP, Millman B, Monheit G, McCollough EG.

Georgia Facial Plastic Surgery, Atlanta, USA.

BACKGROUND: As the number and methods of skin resurfacing procedures

are increasing, there is a small number of patients that develop a

prolonged inflammation during the postoperative period. OBJECTIVE: We

attempted to correlate risk factors for the development of prolonged

postpeel erythema (PPPE) and inflammation. A treatment regimen will

be described to eliminate permanent skin changes. METHODS: A

retrospective chart review is presented to define and correlate risk

factors for the development of PPPE and a treatment protocol is

described. The setting is a large multisurgeon aesthetic center. Two-

hundred and thirty-six consecutive chemical phenol peels on 196

patients over a 2-year period were reviewed. RESULTS: Eleven percent

of patients developed PPPE. Allergy to tape was the only factor

significantly correlated with PPPE. All patients had complete

resolution of skin changes with appropriate treatment. CONCLUSION: A

small population of patients undergoing skin resurfacing procedures

will develop prolonged erythema. No major risk factor could be

correlated with its development. A treatment plan was devised and was

successful in all cases.

PMID: 9537008 [PubMed - indexed for MEDLINE]

-=-=-=

I can't tell what's going on. Does anyone have access to the full-

text article? I see that the first author has moved on to a new

practice:

http://www.advancedsurgerycenter.com/specialties/cosmetic.htm

A second article looks more objective and may have some answers.

(Unfortunately, I don't have full-text access to this journal either):

-=-=-=

J Oral Maxillofac Surg 1999 Jul;57(7):837-41

Diagnosis and treatment of postoperative complications after skin

resurfacing.

Demas PN, Bridenstine JB.

Department of Oral and Maxillofacial Surgery, University of

Pittsburgh Medical Center, PA 15261, USA.

Chemical peel, dermabrasion, and laser skin resurfacing are

alternative methods to achieve skin resurfacing for reconstructive or

cosmetic applications. The potential postoperative complications are

similar with all of these techniques. These postoperative

complications and their therapy are reviewed.

Publication Types:

Review

Review, Tutorial

PMID: 10416632 [PubMed - indexed for MEDLINE]

-=-=-=

Marjorie

Marjorie Lazoff, MD

> Iwish more people would be aware that a chemical peel or laser skin

> resurfacing (which I had) can bring a tendency to blushing into

full

> rosacea. That is what happened to me. I never was bothered by any

> kind of acne or papules before.

> It is too bad that doctors will not even mention this to their

> patients as one of the possible side effects of the procedure.

> Helen

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Helen, an alternative is that aggressive exfoliative treatment causes

an irritative contact dermatitis, and interruption of the epithelial

protective barrier perpetuates the underlying dermatitis. Not

everything that is acneiform is rosacea, even in rosaceans.

So the key may not be easy flushing/blushing, but skin sensitivity

(that is a frequent rosacean feature from pre-condition onwards, but

also affects non-rosaceans) upon which aggressive treatment causes an

inflammatory reaction more common in rosaceans but unrelated to

rosacea itself. I don't know.

To gain more information, I performed a quick Medline search on

various related terms and came up with:

-=-=-=

Dermatol Surg 1998 Mar;24(3):337-41

The etiology of prolonged erythema after chemical peel.

Maloney BP, Millman B, Monheit G, McCollough EG.

Georgia Facial Plastic Surgery, Atlanta, USA.

BACKGROUND: As the number and methods of skin resurfacing procedures

are increasing, there is a small number of patients that develop a

prolonged inflammation during the postoperative period. OBJECTIVE: We

attempted to correlate risk factors for the development of prolonged

postpeel erythema (PPPE) and inflammation. A treatment regimen will

be described to eliminate permanent skin changes. METHODS: A

retrospective chart review is presented to define and correlate risk

factors for the development of PPPE and a treatment protocol is

described. The setting is a large multisurgeon aesthetic center. Two-

hundred and thirty-six consecutive chemical phenol peels on 196

patients over a 2-year period were reviewed. RESULTS: Eleven percent

of patients developed PPPE. Allergy to tape was the only factor

significantly correlated with PPPE. All patients had complete

resolution of skin changes with appropriate treatment. CONCLUSION: A

small population of patients undergoing skin resurfacing procedures

will develop prolonged erythema. No major risk factor could be

correlated with its development. A treatment plan was devised and was

successful in all cases.

PMID: 9537008 [PubMed - indexed for MEDLINE]

-=-=-=

I can't tell what's going on. Does anyone have access to the full-

text article? I see that the first author has moved on to a new

practice:

http://www.advancedsurgerycenter.com/specialties/cosmetic.htm

A second article looks more objective and may have some answers.

(Unfortunately, I don't have full-text access to this journal either):

-=-=-=

J Oral Maxillofac Surg 1999 Jul;57(7):837-41

Diagnosis and treatment of postoperative complications after skin

resurfacing.

Demas PN, Bridenstine JB.

Department of Oral and Maxillofacial Surgery, University of

Pittsburgh Medical Center, PA 15261, USA.

Chemical peel, dermabrasion, and laser skin resurfacing are

alternative methods to achieve skin resurfacing for reconstructive or

cosmetic applications. The potential postoperative complications are

similar with all of these techniques. These postoperative

complications and their therapy are reviewed.

Publication Types:

Review

Review, Tutorial

PMID: 10416632 [PubMed - indexed for MEDLINE]

-=-=-=

Marjorie

Marjorie Lazoff, MD

> Iwish more people would be aware that a chemical peel or laser skin

> resurfacing (which I had) can bring a tendency to blushing into

full

> rosacea. That is what happened to me. I never was bothered by any

> kind of acne or papules before.

> It is too bad that doctors will not even mention this to their

> patients as one of the possible side effects of the procedure.

> Helen

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: " emarjency " writes in reply to Helen regarding

peels:

> aggressive exfoliative treatment causes

> an irritative contact dermatitis, and interruption of the >epithelial

protective barrier perpetuates the underlying >dermatitis.

I have never had a peel, but would consider cosmetic surgery to correct a

few aging concerns ( I am 51 ) but all this talk has made me a little

apprehensive. I don't have pimples, or a bit problem with redness or

flushing/flaring so I don't want to make a mild case into a full blown one.

If I can get a appointment with a derm in " our one derm town " then I will

discuss this with him as well as the plastic surgeon who will perform the

face lift ( I presume ) but while I am waiting ( probably October/

NOvember ) then I would love to know your opinions, experiences and/or

medical expertise. I have tried to do a web search but came up with nothing.

So perhaps those of you who are more well versed in computer searching could

help me with some appropriate descriptors or whatver they are called in

computer language.

Thanks

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Guest guest

: " emarjency " writes in reply to Helen regarding

peels:

> aggressive exfoliative treatment causes

> an irritative contact dermatitis, and interruption of the >epithelial

protective barrier perpetuates the underlying >dermatitis.

I have never had a peel, but would consider cosmetic surgery to correct a

few aging concerns ( I am 51 ) but all this talk has made me a little

apprehensive. I don't have pimples, or a bit problem with redness or

flushing/flaring so I don't want to make a mild case into a full blown one.

If I can get a appointment with a derm in " our one derm town " then I will

discuss this with him as well as the plastic surgeon who will perform the

face lift ( I presume ) but while I am waiting ( probably October/

NOvember ) then I would love to know your opinions, experiences and/or

medical expertise. I have tried to do a web search but came up with nothing.

So perhaps those of you who are more well versed in computer searching could

help me with some appropriate descriptors or whatver they are called in

computer language.

Thanks

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Guest guest

Hi Marjorie,

In your opinion, how long should " post-operative inflammation " last?

my chemical peel was last august (symptoms began 3 months later,

exactly as dr nase predicted!) it has now been almost a year, with

things looking worse not better. since helen's case is rather similar

to mine, i was wondering whether inflammation could have affected cell

renewal ? hence the almost consistent flakiness of certain parts of

the skin? (i think i read somewhere that typically it takes a month to

rejuvenate new layer of skin, dr nase said damaged skin could take up

to 3 months?)maybe ours is even longer?

> > Iwish more people would be aware that a chemical peel or laser

skin

> > resurfacing (which I had) can bring a tendency to blushing into

> full

> > rosacea. That is what happened to me. I never was bothered by any

> > kind of acne or papules before.

> > It is too bad that doctors will not even mention this to their

> > patients as one of the possible side effects of the procedure.

> > Helen

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Guest guest

Hi Marjorie,

In your opinion, how long should " post-operative inflammation " last?

my chemical peel was last august (symptoms began 3 months later,

exactly as dr nase predicted!) it has now been almost a year, with

things looking worse not better. since helen's case is rather similar

to mine, i was wondering whether inflammation could have affected cell

renewal ? hence the almost consistent flakiness of certain parts of

the skin? (i think i read somewhere that typically it takes a month to

rejuvenate new layer of skin, dr nase said damaged skin could take up

to 3 months?)maybe ours is even longer?

> > Iwish more people would be aware that a chemical peel or laser

skin

> > resurfacing (which I had) can bring a tendency to blushing into

> full

> > rosacea. That is what happened to me. I never was bothered by any

> > kind of acne or papules before.

> > It is too bad that doctors will not even mention this to their

> > patients as one of the possible side effects of the procedure.

> > Helen

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Guest guest

> In your opinion, how long should " post-operative inflammation "

> last?

I don't know, , but I would think it is self-limiting --

assuming it is managed appropriatly and there's no further exposure

to irritants so the skin to heal. Otherwise it could go on

indefinitely. I don't see how a single beta chemical peel can cause

permanent skin damage, but dermatology isn't my specialty -- just my

affliction. <g>

> i was wondering whether inflammation could have affected cell

> renewal ? hence the almost consistent flakiness of certain parts of

> the skin?

The cell renewel occurs at (in other words, cell turnover is

controlled by) the basal layer of the epithelium, and responds to

increase or decrease in cells at the uppermost corneum layer. This

process is normal in rosaceans (though it is affected in seborrheic

dermatitis, as those of you familiar with that condition know about).

I don't believe there's a direct relationship between inflammation

and cell turnover. Inflammation wouldn't directly cause gain or loss

of corneum -- but it could indirectly, through treatments for

inflammation that exfoliate.

I may well be wrong, but I would think a more likely explanation for

continued flakiness is a chronically impaired epithelial protective

barrier resulting in dry and overly sensitive skin. (this has nothing

to do with cell renewel, but with ongoing irritation/inflammation,

even at very low levels).

Marjorie

Marjorie Lazoff, MD

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Guest guest

> In your opinion, how long should " post-operative inflammation "

> last?

I don't know, , but I would think it is self-limiting --

assuming it is managed appropriatly and there's no further exposure

to irritants so the skin to heal. Otherwise it could go on

indefinitely. I don't see how a single beta chemical peel can cause

permanent skin damage, but dermatology isn't my specialty -- just my

affliction. <g>

> i was wondering whether inflammation could have affected cell

> renewal ? hence the almost consistent flakiness of certain parts of

> the skin?

The cell renewel occurs at (in other words, cell turnover is

controlled by) the basal layer of the epithelium, and responds to

increase or decrease in cells at the uppermost corneum layer. This

process is normal in rosaceans (though it is affected in seborrheic

dermatitis, as those of you familiar with that condition know about).

I don't believe there's a direct relationship between inflammation

and cell turnover. Inflammation wouldn't directly cause gain or loss

of corneum -- but it could indirectly, through treatments for

inflammation that exfoliate.

I may well be wrong, but I would think a more likely explanation for

continued flakiness is a chronically impaired epithelial protective

barrier resulting in dry and overly sensitive skin. (this has nothing

to do with cell renewel, but with ongoing irritation/inflammation,

even at very low levels).

Marjorie

Marjorie Lazoff, MD

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Guest guest

Hi ,

I had a facelift and the telangetasia became 100 fold. I don't think the ps

new this would happen to my skin. I didn't either but I have read that this

can be a side effect for those of us that have rosecea.

Patty

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Guest guest

Hi ,

I had a facelift and the telangetasia became 100 fold. I don't think the ps

new this would happen to my skin. I didn't either but I have read that this

can be a side effect for those of us that have rosecea.

Patty

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