cea and topical retinoids.

[Guest guest]

Hi group.

This is the first time i post but i have had private contact with

some of you,Hello Dr Majorie, she knows me as the one who calls

himself a doctor.

My name is Ian and i am acctually a Doctor in medicine, i am willing

to help as much as i can so feel free to ask and i will get back to

you as soon as possible,

I will like to say something about Matijas articule because it seems

ironic but is a matter of fact, is well known that retinoic acid is

not a good choice for people with sensitive skin, Not many years ago

if a Dr was thinking in retinoic acid as a choice for rosacea the

medical comunity would of think of a joke or maybe a mistake because

the rosacea is by some considered as some type of acne or adult acne

other investigations say that they look alike and sometimes coesxist

but they are totally diferent diseases if you think about it who is

who to decide or determine if nobody knows the cause of rosacea, i

believe that is multifactorial begining like all diseases with a

genetic charge, in a personal point of view i think there might be

even diferent causes or types of rosacea and maybe that is why some

people responds well to some drugs and others not respond or respond

in a paradoxicall or oposite way, and theories there is the

neurovascular, the demodex mites, the altered temperture regulation

by the hypotalamus,The H pylori as the responsable, the gluten an

inmune mediated etc at least we have ideas, although sometimes it

feels like we are confused and choosing a dark, wrong direccion in

the plans of investigation because although i am not American there

are some 13 millions of rosaceans only in United States even the

expresident has rosacea plus 2 million of Canadians, Australians and

many in Europe and nobody knows what is going on many times i feel

frustrated when i read a Book or an articule wich comfirms that

rosacea is perfectly controled with Metrogel, Dont get me wrong there

are doctors that have being of great help like Dr Nase sadly he have

to had it to understand the impact of rosacea.

Sorry i am loosing the purpose of these post, in recient

investigations retinoic acid at 0.5% or tretinoin at 0.025 at bedtime

combined with the anibiotic clindamicine in the morning has being a

what i call crazy good choice, why crazy because retinoids are well

known as pro angiogenics, vasodilators and irritants all that is a no

no for rosaceans the irony is that after 6 months of clinical trials

and at diferent concentrations retinoic acid improved the

papulopustular component of rosacea but it had a better impact in

decreasing the redness, and the telangiectasia, inflamation in

general and also improved rosacea with post-inflamatory lessions or

pigmented areas also caused by solar damaged this is because

retinoids interfiere with the melanosomes that carry melanocites to

the dermis and epidermis, In a personal experience i had being using

isotretinoin the same substance as accutane but in a cream base wich

is less irritating than tretinoin and sometimes i like to combine it

with topical ketoconazol or an antibiotic like clindamicine or

erytromicine results are good but again in my personal experience.

With rosacea we never know what to expect lets play by it rules lets

try unexpectable treatments with unexpectable results lets stop and

think why continue with something that is not working, i learned that

living with this condition makes you choose between becoming a victim

of some kind of bad karma or become wisely crazy meaning to be able

to laugh at yourself just to reduce the pain and the stress accepting

the fact that there is a problem like many others in life that took

you to modify your expectations but never the meaning that you gave

to your life once, i guess that if i dont take it crazy i will be

the one ending up crazy, i am not saying it shouldnt be taken

seriously and with smart, secure treatments i have heard of rosacea

being treated with zofran wich i dont understand besides the price

the drug blocks serotonin and serotonin is a vasoregulator many times

responsable for depression and migrain headaches wich is basically a

cycle of vasodilation and vasoconstriccion also asociated with

rosacea.

I want to tell you all that we share and understand the same pain

that maybe we dont know how are we going to feel some day but for

shure there are things that are going to make us feel better, i say

lets keep the eyes shining, we are part of the world and things

sometimes are harder for us,sometimes we are judged by people of

complaining, of being wrong,victims, how many times i end up lifting

shadows of broken dreams, insecure of what i am doing, not sleeping

wondering if my life has sense, but i am shure we are not cowards, we

fight, we are warriors sometimes defeated,sad,hopeless all of that

are part of all fighter but we still believe, we look for a meaning

and search for the cause because we ask and some day we will know.

Take care, sorry but english is not my language hope you understand.

Dr Ian Alarcon.

[Guest guest]

Hi group.

This is the first time i post but i have had private contact with

some of you,Hello Dr Majorie, she knows me as the one who calls

himself a doctor.

My name is Ian and i am acctually a Doctor in medicine, i am willing

to help as much as i can so feel free to ask and i will get back to

you as soon as possible,

I will like to say something about Matijas articule because it seems

ironic but is a matter of fact, is well known that retinoic acid is

not a good choice for people with sensitive skin, Not many years ago

if a Dr was thinking in retinoic acid as a choice for rosacea the

medical comunity would of think of a joke or maybe a mistake because

the rosacea is by some considered as some type of acne or adult acne

other investigations say that they look alike and sometimes coesxist

but they are totally diferent diseases if you think about it who is

who to decide or determine if nobody knows the cause of rosacea, i

believe that is multifactorial begining like all diseases with a

genetic charge, in a personal point of view i think there might be

even diferent causes or types of rosacea and maybe that is why some

people responds well to some drugs and others not respond or respond

in a paradoxicall or oposite way, and theories there is the

neurovascular, the demodex mites, the altered temperture regulation

by the hypotalamus,The H pylori as the responsable, the gluten an

inmune mediated etc at least we have ideas, although sometimes it

feels like we are confused and choosing a dark, wrong direccion in

the plans of investigation because although i am not American there

are some 13 millions of rosaceans only in United States even the

expresident has rosacea plus 2 million of Canadians, Australians and

many in Europe and nobody knows what is going on many times i feel

frustrated when i read a Book or an articule wich comfirms that

rosacea is perfectly controled with Metrogel, Dont get me wrong there

are doctors that have being of great help like Dr Nase sadly he have

to had it to understand the impact of rosacea.

Sorry i am loosing the purpose of these post, in recient

investigations retinoic acid at 0.5% or tretinoin at 0.025 at bedtime

combined with the anibiotic clindamicine in the morning has being a

what i call crazy good choice, why crazy because retinoids are well

known as pro angiogenics, vasodilators and irritants all that is a no

no for rosaceans the irony is that after 6 months of clinical trials

and at diferent concentrations retinoic acid improved the

papulopustular component of rosacea but it had a better impact in

decreasing the redness, and the telangiectasia, inflamation in

general and also improved rosacea with post-inflamatory lessions or

pigmented areas also caused by solar damaged this is because

retinoids interfiere with the melanosomes that carry melanocites to

the dermis and epidermis, In a personal experience i had being using

isotretinoin the same substance as accutane but in a cream base wich

is less irritating than tretinoin and sometimes i like to combine it

with topical ketoconazol or an antibiotic like clindamicine or

erytromicine results are good but again in my personal experience.

With rosacea we never know what to expect lets play by it rules lets

try unexpectable treatments with unexpectable results lets stop and

think why continue with something that is not working, i learned that

living with this condition makes you choose between becoming a victim

of some kind of bad karma or become wisely crazy meaning to be able

to laugh at yourself just to reduce the pain and the stress accepting

the fact that there is a problem like many others in life that took

you to modify your expectations but never the meaning that you gave

to your life once, i guess that if i dont take it crazy i will be

the one ending up crazy, i am not saying it shouldnt be taken

seriously and with smart, secure treatments i have heard of rosacea

being treated with zofran wich i dont understand besides the price

the drug blocks serotonin and serotonin is a vasoregulator many times

responsable for depression and migrain headaches wich is basically a

cycle of vasodilation and vasoconstriccion also asociated with

rosacea.

I want to tell you all that we share and understand the same pain

that maybe we dont know how are we going to feel some day but for

shure there are things that are going to make us feel better, i say

lets keep the eyes shining, we are part of the world and things

sometimes are harder for us,sometimes we are judged by people of

complaining, of being wrong,victims, how many times i end up lifting

shadows of broken dreams, insecure of what i am doing, not sleeping

wondering if my life has sense, but i am shure we are not cowards, we

fight, we are warriors sometimes defeated,sad,hopeless all of that

are part of all fighter but we still believe, we look for a meaning

and search for the cause because we ask and some day we will know.

Take care, sorry but english is not my language hope you understand.

Dr Ian Alarcon.