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Re: CDG/Ann

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,

Thank you for asking about Sam's CDG testing. We've been at the

hospital all well so I am just reading the mito digests now.

We actually just did the repeat test this past weeek while he was in

and i think it takes about 3 -4 weeks to come back. (or at least to

make its way from the lab to our doctor). So much has been going on

that I had forgotten to repeat it back in October when we were

supposed to. I doubt it matters.

Regarding IVIg for Vasculitis - do your docs use the 2g/kg dose or

the immune deficient dose (much smaller). I wonder if you used a

higher dose if it would help. We do also use steroids but not in

high amounts.

Darla: so glad that the MRI looked better but sorry that she has to

remain on steroids. Its a double edged sword but in her case it

sounds like it is the right thing to do and so you just do the best

you can. Thank God she responds to them.

and Darla: A little boy I know developed vasculitis about a

month ago. he does not have a known case of mito although there are

times i wonder. Anyway, he had an acute downhill course. he had been

in the hospital just for some routine GI testing and woke up one day

with weakness and trembling and I think peripheral neuropathy.

Withina few days he went into respiratory distress and had to be

placed on a vent, was bleeding out everywhere, uncontrollable blood

pressures and questionable stroke like issues. he cannot walk and

can barely sit up. They tried the high dose IVIG initially to no

avail - the vasculitis continued to progress. They proceeded to slam

him with steroids in amounts I have never personally witnessed in my

nursing experience. Thankfully that was the right thing to do and he

is now out of the ICU and heading to a rehab hospital. For a time

they talked about using cytoxan I believe (chemotherapy which is used

for some cases of vasculitis). It was all so sudden and made me

thankful that sammy's has never progressed to that extent of being

placed on a vent.

Anne

>

> Ann,

> How have the last round of CDG tests come out? Any more news on the

> matter?

> Just curious..

>

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,

Thank you for asking about Sam's CDG testing. We've been at the

hospital all well so I am just reading the mito digests now.

We actually just did the repeat test this past weeek while he was in

and i think it takes about 3 -4 weeks to come back. (or at least to

make its way from the lab to our doctor). So much has been going on

that I had forgotten to repeat it back in October when we were

supposed to. I doubt it matters.

Regarding IVIg for Vasculitis - do your docs use the 2g/kg dose or

the immune deficient dose (much smaller). I wonder if you used a

higher dose if it would help. We do also use steroids but not in

high amounts.

Darla: so glad that the MRI looked better but sorry that she has to

remain on steroids. Its a double edged sword but in her case it

sounds like it is the right thing to do and so you just do the best

you can. Thank God she responds to them.

and Darla: A little boy I know developed vasculitis about a

month ago. he does not have a known case of mito although there are

times i wonder. Anyway, he had an acute downhill course. he had been

in the hospital just for some routine GI testing and woke up one day

with weakness and trembling and I think peripheral neuropathy.

Withina few days he went into respiratory distress and had to be

placed on a vent, was bleeding out everywhere, uncontrollable blood

pressures and questionable stroke like issues. he cannot walk and

can barely sit up. They tried the high dose IVIG initially to no

avail - the vasculitis continued to progress. They proceeded to slam

him with steroids in amounts I have never personally witnessed in my

nursing experience. Thankfully that was the right thing to do and he

is now out of the ICU and heading to a rehab hospital. For a time

they talked about using cytoxan I believe (chemotherapy which is used

for some cases of vasculitis). It was all so sudden and made me

thankful that sammy's has never progressed to that extent of being

placed on a vent.

Anne

>

> Ann,

> How have the last round of CDG tests come out? Any more news on the

> matter?

> Just curious..

>

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Share on other sites

That is so scary to hear about! Oh, I am just feeling horrible for not only

the child, but for the parents! This issue is so unknown and so hard to

treat. We don't know what to expect ever with it, do we? I know most of

the time it is found on autopsy so have always felt blessed Asenath's was

found when it was. We thought 1 narrow artery to 4 narrow arteries in a

year was bad, but that poor child's case is so scary. I am glad to hear the

steroids helped. How much did they use? We were told Asenath's amount was

extremely high (It was started at 10 ml per day with the dosage being a 15

mg/5 ml. liquid solution). Was it much higher than that? Cytoxin was

actually the other drug considered for Asenath. We knew we couldn't risk

giving it to her when we began because not only was she way undernourished

at the time but it was also the fall with the winter months approaching and

she caught every small virus around. Thanks for sharing this information

with me. I would appreciate keeping updated and if you still have contact

with them, let them know about our case and progress as well as let them

know if they would like to talk on the phone, I would be open to that. It

is such a rare case that it sometimes helps to talk to those of us who have

been through it. You or they can write to me at honeybear50317@... to

get my phone number or to give me theirs.

Thanks again. I will be praying for them.

See www.caringbridge.org/ia/mitomomof9 and this link to see a real look into

Mito using a photo collage of my girls at www.heartbeatsformito.org

Darla: mommy to

Asenath (4) Mito, CNS Vasculitis, strokes, migraines, seizures, G-tube,

hypotonicity, disautonomy, SID, dev. delays, asthma, cyclic vomiting...

Zipporrah (12 months) Mito, strokes, neuro-motor planning dysfunction, SID,

GERD, 100% G-tube fed, asthma, trach issues, aberrant subclavian artery,

disautonomy, hypo & hypertonicity, migraines, possible seizures, dumping

syndrome, iron deficiency...

Luke (16), Leah (14), Rachael (12), Isaac (10), Tirzah (8), Kezia (3), &

Marquis (2) (some with Mito symptoms)

Re: CDG/Ann

>

>

>

> ,

> Thank you for asking about Sam's CDG testing. We've been at the

> hospital all well so I am just reading the mito digests now.

>

> We actually just did the repeat test this past weeek while he was in

> and i think it takes about 3 -4 weeks to come back. (or at least to

> make its way from the lab to our doctor). So much has been going on

> that I had forgotten to repeat it back in October when we were

> supposed to. I doubt it matters.

>

> Regarding IVIg for Vasculitis - do your docs use the 2g/kg dose or

> the immune deficient dose (much smaller). I wonder if you used a

> higher dose if it would help. We do also use steroids but not in

> high amounts.

>

> Darla: so glad that the MRI looked better but sorry that she has to

> remain on steroids. Its a double edged sword but in her case it

> sounds like it is the right thing to do and so you just do the best

> you can. Thank God she responds to them.

>

> and Darla: A little boy I know developed vasculitis about a

> month ago. he does not have a known case of mito although there are

> times i wonder. Anyway, he had an acute downhill course. he had been

> in the hospital just for some routine GI testing and woke up one day

> with weakness and trembling and I think peripheral neuropathy.

> Withina few days he went into respiratory distress and had to be

> placed on a vent, was bleeding out everywhere, uncontrollable blood

> pressures and questionable stroke like issues. he cannot walk and

> can barely sit up. They tried the high dose IVIG initially to no

> avail - the vasculitis continued to progress. They proceeded to slam

> him with steroids in amounts I have never personally witnessed in my

> nursing experience. Thankfully that was the right thing to do and he

> is now out of the ICU and heading to a rehab hospital. For a time

> they talked about using cytoxan I believe (chemotherapy which is used

> for some cases of vasculitis). It was all so sudden and made me

> thankful that sammy's has never progressed to that extent of being

> placed on a vent.

>

> Anne

>

>

> >

> > Ann,

> > How have the last round of CDG tests come out? Any more news on the

> > matter?

> > Just curious..

> >

>

>

>

>

>

>

> Please contact mito-owner with any problems or questions.

>

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Share on other sites

That is so scary to hear about! Oh, I am just feeling horrible for not only

the child, but for the parents! This issue is so unknown and so hard to

treat. We don't know what to expect ever with it, do we? I know most of

the time it is found on autopsy so have always felt blessed Asenath's was

found when it was. We thought 1 narrow artery to 4 narrow arteries in a

year was bad, but that poor child's case is so scary. I am glad to hear the

steroids helped. How much did they use? We were told Asenath's amount was

extremely high (It was started at 10 ml per day with the dosage being a 15

mg/5 ml. liquid solution). Was it much higher than that? Cytoxin was

actually the other drug considered for Asenath. We knew we couldn't risk

giving it to her when we began because not only was she way undernourished

at the time but it was also the fall with the winter months approaching and

she caught every small virus around. Thanks for sharing this information

with me. I would appreciate keeping updated and if you still have contact

with them, let them know about our case and progress as well as let them

know if they would like to talk on the phone, I would be open to that. It

is such a rare case that it sometimes helps to talk to those of us who have

been through it. You or they can write to me at honeybear50317@... to

get my phone number or to give me theirs.

Thanks again. I will be praying for them.

See www.caringbridge.org/ia/mitomomof9 and this link to see a real look into

Mito using a photo collage of my girls at www.heartbeatsformito.org

Darla: mommy to

Asenath (4) Mito, CNS Vasculitis, strokes, migraines, seizures, G-tube,

hypotonicity, disautonomy, SID, dev. delays, asthma, cyclic vomiting...

Zipporrah (12 months) Mito, strokes, neuro-motor planning dysfunction, SID,

GERD, 100% G-tube fed, asthma, trach issues, aberrant subclavian artery,

disautonomy, hypo & hypertonicity, migraines, possible seizures, dumping

syndrome, iron deficiency...

Luke (16), Leah (14), Rachael (12), Isaac (10), Tirzah (8), Kezia (3), &

Marquis (2) (some with Mito symptoms)

Re: CDG/Ann

>

>

>

> ,

> Thank you for asking about Sam's CDG testing. We've been at the

> hospital all well so I am just reading the mito digests now.

>

> We actually just did the repeat test this past weeek while he was in

> and i think it takes about 3 -4 weeks to come back. (or at least to

> make its way from the lab to our doctor). So much has been going on

> that I had forgotten to repeat it back in October when we were

> supposed to. I doubt it matters.

>

> Regarding IVIg for Vasculitis - do your docs use the 2g/kg dose or

> the immune deficient dose (much smaller). I wonder if you used a

> higher dose if it would help. We do also use steroids but not in

> high amounts.

>

> Darla: so glad that the MRI looked better but sorry that she has to

> remain on steroids. Its a double edged sword but in her case it

> sounds like it is the right thing to do and so you just do the best

> you can. Thank God she responds to them.

>

> and Darla: A little boy I know developed vasculitis about a

> month ago. he does not have a known case of mito although there are

> times i wonder. Anyway, he had an acute downhill course. he had been

> in the hospital just for some routine GI testing and woke up one day

> with weakness and trembling and I think peripheral neuropathy.

> Withina few days he went into respiratory distress and had to be

> placed on a vent, was bleeding out everywhere, uncontrollable blood

> pressures and questionable stroke like issues. he cannot walk and

> can barely sit up. They tried the high dose IVIG initially to no

> avail - the vasculitis continued to progress. They proceeded to slam

> him with steroids in amounts I have never personally witnessed in my

> nursing experience. Thankfully that was the right thing to do and he

> is now out of the ICU and heading to a rehab hospital. For a time

> they talked about using cytoxan I believe (chemotherapy which is used

> for some cases of vasculitis). It was all so sudden and made me

> thankful that sammy's has never progressed to that extent of being

> placed on a vent.

>

> Anne

>

>

> >

> > Ann,

> > How have the last round of CDG tests come out? Any more news on the

> > matter?

> > Just curious..

> >

>

>

>

>

>

>

> Please contact mito-owner with any problems or questions.

>

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