Guest guest Posted November 12, 2004 Report Share Posted November 12, 2004 I did briefly look through the recent article on Vitamin E. basically the writers had compiled many different studies by many different groups. Several statisticians criticized that approach, saying that it was very miss leading to do that because the studies were different of course. Others found it to be a valid way to get a lot of information. That having been said, if you believe the report, it showed that people on higher doses of Vit E, did die more and younger than those not on Vit E supplementation (or smaller doses). Although the editorialists are arguing about whether it is harmful or not to take > 400 IU/day of Vit E, one of the conclusions that all seemed to agree on was that the Vitamin E was not helpful in large doses, even if not harmful. I believe the study is in New Eng Journal Medicine. I think it is crucial that we all understand why Vitamin E has been prescribed by cardiologists. Yes, it is an anti oxidant and oxidative damage contrubutes to heart failure. But also it has a blood thinning effect, so in individuals with a tendency to clog their arteries and have a heart attack - this is a good thing. Flip that though and think about the effect on an individual who has a tendency to bleed or who is going to surgery. Not a good thing. One of the first things our docs looked at when Sam developed his bleeding disorder was his Vitamin E level - they were scared he was toxic. (he was not). This is a very real issue - there is an HIV drug that had some Vit E in it and it proved to be too much for infants - they developed bleeding - finally some researchers figured out it was the Vitamin E. Darla - you mentioned that your kids are on 800 IU. In previous posts you have mentioned bleeding and bruising. Have the docs considered that the Vit E might be contributing to that? Our children's hospital pharmacy is very conservative with the amount of Vitamin E that kids get. The highest they have ever let sam have is 200/day and even that worries them. (Sam is 40 lbs) One last thing - for those of you using the Epic products - the gel caps have significant amounts of Vitamin E in them. if your child is having bruising/bleeding think about that when considering what could be the cause. And always disclose the amount of Vitamin E being taken before a surgery. Anne Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 21, 2004 Report Share Posted November 21, 2004 On this last trip to Mayo Dr. Whiteman reduced Asenath's Vit. E to 400 IU per day in hopes that she would tolerate it better. Her COQ10 was also cut. He didn't seem too concerned about the issue with the Vit. E but did comment that too much could be dangerous. See www.caringbridge.org/ia/mitomomof9 and this link to see a real look into Mito using a photo collage of my girls at www.heartbeatsformito.org Darla: mommy to Asenath (4) Mito, CNS Vasculitis, strokes, migraines, seizures, G-tube, hypotonicity, disautonomy, SID, dev. delays, asthma, cyclic vomiting... Zipporrah (12 months) Mito, strokes, neuro-motor planning dysfunction, SID, GERD, 100% G-tube fed, asthma, trach issues, aberrant subclavian artery, disautonomy, hypo & hypertonicity, migraines, possible seizures, dumping syndrome, iron deficiency... Luke (16), Leah (14), Rachael (12), Isaac (10), Tirzah (8), Kezia (3), & Marquis (2) (some with Mito symptoms) vitamin E > I did briefly look through the recent article on Vitamin E. basically the > writers had compiled many different studies by many different groups. > Several statisticians criticized that approach, saying that it was very > miss leading to do that because the studies were different of course. > Others found it to be a valid way to get a lot of information. > > That having been said, if you believe the report, it showed that people on > higher doses of Vit E, did die more and younger than those not on Vit E > supplementation (or smaller doses). Although the editorialists are > arguing about whether it is harmful or not to take > 400 IU/day of Vit E, > one of the conclusions that all seemed to agree on was that the Vitamin E > was not helpful in large doses, even if not harmful. I believe the study > is in New Eng Journal Medicine. > > I think it is crucial that we all understand why Vitamin E has been > prescribed by cardiologists. Yes, it is an anti oxidant and oxidative > damage contrubutes to heart failure. But also it has a blood thinning > effect, so in individuals with a tendency to clog their arteries and have > a heart attack - this is a good thing. > > Flip that though and think about the effect on an individual who has a > tendency to bleed or who is going to surgery. Not a good thing. One of > the first things our docs looked at when Sam developed his bleeding > disorder was his Vitamin E level - they were scared he was toxic. (he was > not). This is a very real issue - there is an HIV drug that had some Vit E > in it and it proved to be too much for infants - they developed bleeding - > finally some researchers figured out it was the Vitamin E. > > Darla - you mentioned that your kids are on 800 IU. In previous posts you > have mentioned bleeding and bruising. Have the docs considered that the > Vit E might be contributing to that? Our children's hospital pharmacy is > very conservative with the amount of Vitamin E that kids get. The highest > they have ever let sam have is 200/day and even that worries them. (Sam is > 40 lbs) > > One last thing - for those of you using the Epic products - the gel caps > have significant amounts of Vitamin E in them. if your child is having > bruising/bleeding think about that when considering what could be the > cause. And always disclose the amount of Vitamin E being taken before a > surgery. > > Anne > > > Quote Link to comment Share on other sites More sharing options...
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