Guest guest Posted August 22, 2000 Report Share Posted August 22, 2000 What is DMG and TMG? << Have heard a tape recording of Dr Rimland this morning about DMG and TMG They are reporting HIGH doses are stopping seizures, even in kids taking 3-5 pharmacraps a day. Why not try it? I give my kids TMG with Folic and B-12 from www.kirkmanlabs.com . High doses would equal around 15-20 tabs and or whatever that equates in a powder formulation. >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 8, 2004 Report Share Posted November 8, 2004 My doctor and nutritionist told me that reactions were either, bad, very good, or no effect, and that it was difficult to tell before trying, which would work. Also, some children do well with TMG, and some with DMG. After reading a bit on metallothionein, methylation and genetics, and with the advice of a nutritionist, I tried a very small dose of TMG. My son reacted pretty horribly, lots of perseverative play, dark circles under his eyes, huge processing delays. This lasted about 7 days. I gave him about 45 milligrams with a little bit of folinic acid and methyl b-12, so that might have been part of it. Subsequently, I have been reading on the chelating2 listserve. There is a note there from Dr. Neubrander, basically saying he does not recommend that anyone do TMG without doing methyl b-12, then folinic first. The letter is in the files section. I wish I had read it first, but I do think that all kids are different, and I'm sure others here will report that they have had success with this. The letter is good though, because it explains some of why it may or may not work. Judy > > > New to this group. Anyone have info and/or experience with DMG or > TMG? thanks Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2004 Report Share Posted November 9, 2004 > > > New to this group. Anyone have info and/or experience with DMG or > TMG? thanks We tried TMG for a month, but didn't notice any positive changes. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 9, 2004 Report Share Posted November 9, 2004 My son is on TMG w/ B12 injections and Folinic. He is also on many other therapies but in general we are seeing positive results. Not the major leap I was hoping for but slow but steady. No negative reactions to TMG. Maybe slightly more hyper at times but not a bad hyper. > > > > > > > > New to this group. Anyone have info and/or experience with DMG or > > TMG? thanks Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 6, 2008 Report Share Posted January 6, 2008 http://www.autism.org/dmg.html Di-methyl-glycine (DMG) Written by M. Edelson, Ph.D. Center for the Study of Autism, Salem, Oregon DMG is another nutrient that, according to reports from thousands of families, is quite beneficial to many autistic individuals. Similar to vitamin B6 and magnesium, DMG is safe, relatively inexpensive, and helps about half of autistic children and adults. Research on humans and laboratory animals have shown that DMG strengthens the immune system. The immune system is dysfunctional in many autistic individuals. Some autistic children and adults have seizures, and there are two published reports of decreases in seizure activity as a result of DMG (/New England Journal of Medicine,/ 1982, /307,/ 1081-1082; /Epilepsia,/ 1989, /30,/ 90-93). Two studies have shown no improvements from DMG in autistic individuals; however, at least one of the studies used only half the recommended dose. A recent double-blind placebo-controlled study involving 84 participants doc-umented a significant decrease in behavior problems (Unpublished study by Drs. Shin-siung Jung, Bernard Rimland, and M. Edelson). The recommended daily dose of DMG is between one to four 125 mg tablets for a child, and between two and eight tablets for an adult. Initially, a person should begin with one 125 mg tablet (a 1/2 tablet for a small child), and then increase the amount by one tablet every 2 to 3 days. DMG is also available in capsule, liquid, and sweet-tasting dissolving tablets. There are no documented long-term side effects from DMG; however, in a few cases, parents report agitation and/or hyperactivity in their children. In these cases, it is recom-mended that folic acid also be given to the person. The suggested amount is two 800 microgram tablets for each 125 mg tablet of DMG. Some professionals suggest that DMG should always be supplemented with folic acid since folic acid cannot cause any harm, reduces the possibility of agitation/hyperactivity, and could possibly be more effective than when giving DMG alone. Parents have also reported positive results with a similar product, tri-methyl-glycine (TMG). There are, as yet, no published reports on its efficacy for autistic individuals. TMG breaks down into DMG and SAMe in the body. SAMe is a nutritional supplement and is sometimes used to treat mood disorders such as depression. ------------------------------------------------------------------------ ©2002, Copyright information <http://www.autism.org/copyright.html> Quote Link to comment Share on other sites More sharing options...
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