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DMG -- Dimethylglycine

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Starting a new thread to correct some DMG information. I am quoting

directly from Jon Pangborn's book

http://www.amazon.com/Autism-Biomedical-Treatments-Everything-Individual\

ity/dp/0974036099/ref=sr_1_1?ie=UTF8 & s=books & qid=1199603371 & sr=1-1

<http://www.amazon.com/Autism-Biomedical-Treatments-Everything-Individua\

lity/dp/0974036099/ref=sr_1_1?ie=UTF8 & s=books & qid=1199603371 & sr=1-1>

· DMG provides chemical parts needed for folate to do its many

jobs

· For autism, relatively high doses of DMG can have positive

results for speech and eye contact; the data set is anecdotal but huge,

n=5000.

· Start with low trial doses.

Dimethylglycine is the amino acid glycine with two attached methyls that

can be given away. When DMG gives away the first methyl, it becomes

sarcosine, and the donated methyl can add onto tetrahydrofolate (THF).

......

Many clinicians have reported elevation of folate in blood serum for

some autistics. Irritability, hyperactivity and stimming are reported

to increase when these same individuals supplement folate....

Conjectured is a block or " trap' in folate metabolism, a situation where

folate accumulates in some form because a needed helping nutrient,

cofactor, or enzyme is inadequate. Also postulated is poor transport of

folate from serum into cells with some anecdotal reports indicating low

RBC folate. But when DMG is supplemented, we have a huge number of

reports about reduced irritability, hyperactivity and stimming, and the

beginnings of improvement in speech. In fact, improved behavior and/or

speech is reported in over 40% of autistics per nearly 5000 parent

response to ARI.

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