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Re: Major News (Myst)

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You had asked another family about children in the family, who were/were not affected by mito.

Our family has 5 children, and only one is affected. Our oldest (10 years) is from my husbands first marrage, Our two older girls (7 and 6) are from my first marrage and not affected. My husband and I have two children together (2 years, and 3months), the two year old is affected.

Our child who is affected had an undoubtable positive diagnosis from a fresh muscle biopsy so there is nobody who could argue that she does not have mito. The other children are healthy so I would have a hard time thinking they could be affected.

The doctor who told you this really needs a genetic lesson. There are two ways of inheriting mito. You can inherit it either soley from your mother, or from a gene from both parents. If it is inherited from both parents, all there children will have a 1 in 4 shot of becoming affected. If it is passed from the mother, all of her children have a 50/50 shot of being affected. Dr. Cohen believes our daugter was affected by a gene that both my husband and I have. (Although it is a strong theory, and not proven.) We had done some serious considerations on this, when we were thinking of having our last baby. We ended up knowing he had a 25% shot of having mito, but we put it in higher hands and thankfully he was born healthy.

Best wishes.

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