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Cytochrome P450 function in mitochondrial disease?

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My primary care doctor (a mainstream, allopathic physician) suggested

I may have a mitochondrial disorder. Meanwhile, a physician of

alternative medicine suggests that a major deficiency in my liver's

cytochrome P450 enzymes (AKA the phase I detoxification system) plays

a role in my symptoms.

Is deficiency in the CYP450 system seen in mitochondrial disorder? If

so, is there any thinking as to whether one of those issues might be

responsible for the development of the other (or if they might result

from a common cause)?

Thanks.

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