Re: Adrenarche vs. puberty - Kim

[Guest guest]

Pat,

I don't really have the answer about when to start using an aromatase inhibitor.

I think it

may depend on when bone age starts advancing and/or you start seeing physical

signs of

adrenarche (body odor, pubic/underarm hair, acne, etc.), but don't quote me on

this! I

think we really missed the boat a long time ago though. We though was

in

precocious puberty, because of all the signs, but test results didn't confirm

this. I didn't

have the official RSS diagnosis until last summer at the convention when

was 9.75

years. Dr. H recommended he start the aromatase inhibitor, but his local endo

knew

nothing about this & was not going to prescribe something he wsan't familiar

with. After

we saw Dr. H again in New York, he agreed to give this a trial, and we didn't

actually start

Aromasin until was 10 yrs. 4 mos. old. If it is helpful to you & others

who may be

wondering, I will post what 's bone ages/heights/weights were at various

ages as

well as pertinent data related to adrenarche so you can see how he progressed.

CA = chronological age; BA=bone age; Ht = height; Wt = weight

Birth: Ht = 11 " ; Wt = 15 oz. (440 grams)

CA = 14 mos; BA = 0-3 mos; Ht = 23 " ; Wt = 10.5 lbs.

CA = 27 mos; BA = 18 mos; Ht = 28.75 " ; Wt = 18 lbs.

CA = 39 mos; BA = 36 mos; Ht = 32.5 " ; Wt = 24.75 lbs.

CA = 4-4; BA = 5-0; Ht = 36.5 " ; Wt = 31 lbs. *bone age advance & body odor

at 3-10

CA = 5-4; BA = 6-0; Ht = 40 " ; Wt = 31 lbs. * pubic hair onset 4-6; breast

bud 5-0

CA = 6-5; BA = 7-8; Ht = 41 " ; Wt = 36 lbs. * tanner III pubic hair 5-8

CA = 7-1; BA = 9-0; Ht = 42.5 " ; Wt = 39 lbs.

CA = 8-0; BA = 11-0; Ht = 45 " ; Wt = 46 lbs. * huge bone age advance; start

GH at 7-8

CA = 8-6; BA = 11-6; Ht = 46 " ; Wt = 47 lbs. * start Lupron Depot at

8-3

CA = 9-7; BA = 12-6; Ht = 48.75 " ; Wt = 50.5 lbs. *stop Lupron Depot at 9-10

CA = 10-4; BA =12-6; Ht = 50 " ; Wt = 48 lbs. * start Aromasin at 10-4

CA = 10-10; BA = 12-6?; Ht = 50.25 " ; Wt = 48 lbs. * restart Lupron Depot at

10-9

I hope you are able to read/understand this, as I am not sure how the format

will look in

the post! If you have any questions, feel free to email me privately.

Kim C.

> Hi Kim,

>

> I have a question. We got 's blood work back right after the

> convention (big help right? LOL) From the results, Dr H believes that he is

> in premature adrenarche NOW at 32 months of age. 's last bone age

> showed " no delay " . But all that Dr H has us doing for now, is watching his

> weight. He's a little chunk, as anyone at the convention can tell you! LOL

> At what point to do start using an aromatase inhibitor?? This will be a

> major fight with our current endo here at home!

>

> Thanks for the info.

> Pat (g-ma to , RSS, 32 months (today!!), 22.5#, 31.8 " , G-Tube)