Rich Murray: : fibromyalgia & aspartame & MSG 6.27.1 rmforall

[Guest guest]

Rich Murray: : fibromyalgia & aspartame & MSG 6.27.1 rmforall

Ann Pharmacother 2001 Jun;35(6):702-6

Relief of fibromyalgia symptoms following

discontinuation of dietary excitotoxins.

JD, Terpening CM, Schmidt SO, Gums JG.

Malcolm Randall Veterans Affairs Medical Center, Gainesville, FL, USA.

BACKGROUND: Fibromyalgia is a common

rheumatologic disorder that is often difficult to treat

effectively. CASE SUMMARY: Four patients

diagnosed with fibromyalgia syndrome for two to

17 years are described. All had undergone

multiple treatment modalities with limited success. All

had complete, or nearly complete, resolution

of their symptoms within months after eliminating

monosodium glutamate (MSG) or MSG plus aspartame from their diet.

All patients were women with multiple comorbidities

prior to elimination of MSG. All have had recurrence of symptoms

whenever MSG is ingested. DISCUSSION:

Excitotoxins are molecules, such as MSG and

aspartate, that act as excitatory neurotransmitters,

and can lead to neurotoxicity when used in

excess. We propose that these four patients may

represent a subset of fibromyalgia syndrome

that is induced or exacerbated by excitotoxins or,

alternatively, may comprise an excitotoxin

syndrome that is similar to fibromyalgia.

We suggest that identification of similar patients and

research with larger numbers of patients must be

performed before definitive conclusions can be

made. CONCLUSIONS: The elimination of

MSG and other excitotoxins from the diets of

patients with fibromyalgia offers a benign treatment

option that has the potential for dramatic

results in a subset of patients. PMID: 11408989

****************************************

Ann Pharmacother 1998 Feb;32(2):196-200

Possible lansoprazole-induced eosinophilic syndrome.

JD, Chang KL, Gums JG.

Department of Pharmacy Practice

University of Florida, Gainesville, USA.

OBJECTIVE: To report a case of myalgia with

eosinophilia related to lansoprazole

administration. CASE SUMMARY: A 50-year-old white

woman developed severe myalgia 1 week after

starting lansoprazole. During the

treatment course, the patient was also found to have

eosinophilia. The myalgia and eosinophilia

resolved 40 days after lansoprazole was stopped and

18 days after prednisone therapy was begun. The

patient was not rechallenged with lansoprazole.

DISCUSSION: To our knowledge, this is the first

reported case of lansoprazole-induced

eosinophilic syndrome. Clinically, it is

difficult to distinguish between eosinophilia-myalgia

syndrome and eosinophilic fasciitis, which are

probably part of a continuum of eosinophilic

disorders. This patient presented with symptoms

of both syndromes. Although other causes

cannot be completely ruled out, the time course

strongly suggests that lansoprazole was the

causative agent. CONCLUSIONS: It is important to

consider medications when diagnosing

patients with hypereosinophilia and/or myalgia.

PMID: 9496405

Expert Opin Pharmacother 1999 Nov;1(1):71-80

Management of essential hypertension.

Terpening C, Gums JG, Grauer K. terpening@...

University of Florida, Departments of Pharmacy

Practice and Family Medicine

625 SW 4th Ave., Gainesville, FL 32601, USA.

terpening@...

Hypertension, in spite of a very high prevalence,

remains undertreated. This is not due to a lack of

effective therapeutic modalities.

Non-pharmacological treatments can be effective in many

patients. If those treatments fail to reduce

blood pressure sufficiently, the physician can choose

between numerous classes of antihypertensive

agents. However, interpatient variability in

response to these agents is high, and use of

multiple agents is frequently necessary. Thus, no

single class has proven to be superior for the

majority of patients. This article will review the

different non-pharmacological and pharmacological

methods available to treat hypertension, as

well as the guidelines that are available to aid

in proper selection of a treatment regimen.

Publication Types: Review Review, tutorial

PMID: 11249566

Terpening CM.

The FDA: protector or puppet?

Pharmacotherapy. 2000 Jul;20(7):860-1. No abstract available.

PMID: 10907979

Gums JG.

Empathy to apathy: a consequence of higher education?

Pharmacotherapy. 1994 Mar-Apr;14(2):250-1.

No abstract available. PMID: 8197049

Miles Terpening

Information current as of: 09/09/1999

post doc aso pharmacy practice,uf

Campus mg-58 445

po box 100486 gainesville fl 32610-0486

Home u of f box 100846 gvn fl fl 32611

Email cterpeni@...

G Gums

Information current as of: 09/28/1999

professor pharmacy practice,uf

Campus j486 jhmhc

po box 100486 gainesville fl 32610-0486

Home 3626 nw 23rd pl gainesville fl 32605-2666

Email gums@...

Siegfried O Schmidt

Information current as of: 01/27/1900

clin ast prof community hlth & fam med,uf

Campus w oak clnic

po box 103588 gainesville fl 32610-3588

Home 8120 sw 36th ave gainesville fl 32608-3629

Email siggy@...

***************************************************************

Rich Murray, MA Room For All rmforall@...

1943 Otowi Road, Santa Fe NM USA 87505

M.I.T. (physics and history, BA, 1964), Boston U. Graduate School

(psychology, MA, 1967): As a concerned layman, I want to clarify the

aspartame toxicity debate.

http://groups.yahoo.com/group/aspartameNM/message/618

long 40K summary

Excellent 5-page review by H.J. in " Townsend Letter " ,

Jan 2000, " Aspartame (NutraSweet) Addiction "

http://www.dorway.com/tldaddic.html http://www.sunsentpress.com/

H.J. , M.D. HJmd@... sunsentpress@...

Sunshine Sentinel Press 6708 Pamela Lane West Palm Beach, FL 33405

fax

1038 page text " Aspartame Disease: An Ignored Epidemic "

published May 30 2001 $ 85.00 postpaid data from 1200 cases

http://www.aspartameispoison.com/contents.html 34 chapters

*********************************************************