Guest guest Posted June 8, 2001 Report Share Posted June 8, 2001 Hi All, Please forgive me if this information has been posted here before. I do not always read everything here. I came across the study pasted below yesterday, even though it was published a year ago. The authors seem to be concentrating on the IgG and IgA antibodies to gluten and casein. I believe that these are indications of " conventional " allergies to these proteins and not necessarily of the opioid theory. Have any of you had your kids tested for a conventional allergic response to gluten or casein? This seems to me to be a very significant study! 90% of autistic kids having a conventional allergy to cow's milk seems at least as important as the recent Pfeiffer Treatment Center results on Copper/Zinc imbalances: http://www.hriptc.org/MetalMetabolism_and_Autism.htm Autism and Schizophrenia: Intestinal Disorders Nutritional Neuroscience, An International Journal on Nutrition, Diet and Nervous System, June 2000, vol. 1, no. 6, pp. 1-16(16) Cade R.; Privette M.; Fregly M.; Rowland N.; Sun Z.; Zele V.; Wagemaker H.; Edelstein C. Departments of Medicine, Physiology, Psychology and Psychiatry, University of Florida, Gainesville, FL 32610-0204, USA Abstract: We examined Dohan's hypothesis that schizophrenia is associated with the absorption of " exorphins " contained in gluten and casein. In addition, because of the work of Reichelt et al. (Reichelt, K.L., Saelid, G., Lindback, J. and Orbeck, H. (1986) Biological Psychiatry 21: 1279–1290) and et al. (, Trav, A.L., Barreiro Marin, P., Galvez, Borrero, I.M., del Olmo Romero-Nieva, F. and Alvarez, A. (1994) Journal of Nervous and Mental Disease Aug; 182(8): 478–479), we carried out similar studies on a group of children with autism. In both syndromes we found similar patterns of peptide containing peaks (Ninhydrin positive) after molecular screening with Sephadex G-15. Immunoglobulin assay of IgA and IgG against gliadin and casein in serum was done. High titer IgG antibodies to gliadin were found in 87% of autistic and 86% of schizophrenic patients and high titer IgG antibodies to bovine casein were found in 90% of autistic and in 93% of schizophrenic patients. High titer IgA antibodies to gluten or casein were found in 30% of children with autism while in schizophrenic patients 86% had elevated IgA antibodies to gluten and 67% to casein; some normal children and adults have these antibodies but only in trace amounts. When schizophrenic patients were treated with dialysis or a gluten–casein free diet, or both (Cade, R., Wagemaker, H., Privette, R.M., Fregly, M., , J. and Orlando, J. (1990) Psychiatry: A World Prespective 1: 494–500) peptiduria and Brief Psychiatric Rating Scores fell while abnormal behavior diminished. A gluten–casein free diet was accompanied by improvement in 81% of autistic children within 3 months in most of the behavior categories. Our data provide support for the proposal that many patients with schizophrenia or autism suffer due to absorption of exorphins formed in the intestine from incomplete digestion of gluten and casein. Keywords: Gluten; Casein; Schizophrenia; Autism; Gliadorphin; -Casomorphin; Diet Language: EN Document Type: SA Publisher: Gordon and Breach Publishing Group Quote Link to comment Share on other sites More sharing options...
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