Jody- Stanhope's answer re kidney/urinary problems

[Guest guest]

Jody - I don't know if I can do that, because I would need to ask

his permission. He said I could use his answers to communicate to

the RSS parents. Is it because you want to be able to show it came

from " him " versus me? Write me privately.

> >

> > Hello again,

> >

> > Jen Salem here. The other questions you all raised was about the

> > WebMD Health website and Medline Plus Encyclopedia saying that

RSS

> > children are at risk for " abnormalities of the kidney and

urinary

> > tract, and at an increased risk for liver tumors. "

> >

> > Stanhope replied with the following:

> >

> > " You [me/Jen]are quite right that there are abnormalities of the

> > urinary tract associated with RSS. This usually includes

> > hypospadius, undescended testes, as well as inguingal herniae.

> > These are just more common than in normal boys. Because there

is

> an

> > increased incidence of hypospadius, there must be an increased

> > incidence of other abnormalities of the urinary tract, although

I

> do

> > not now the evidence for this. The two features of upper and

> lower

> > urinary congenital tract abnormalities usually go together.

> >

> > And you are correct in the belief that it is important to

> > distinguish between hypoplasia of one limb, or hyperplasia of

the

> > contralateral limb. In cases of the latter, this is associated

> with

> > Wilm's tumors, but not the former. There are many conditions

> > associated with limb asymmetry and RSS is just one of them. "

> >

> > SO, if you do not understand any of that .... I emailed him back

> to

> > clarify. And essentially it is this:

> >

> > Those websites above still have some incorrect info!!!

> >

> > RSS kids definitely have an increased incidence of urinary tract

> > abnormalities, and as Dr. Stanhope wrote, because the upper and

> > lower are connected, it is appropriate to monitor the upper as

> well,

> > which means the kidneys. So not that RSS kids necessarily have

> been

> > found to have kidney problems more often, but that because of

the

> > lower urinary tract problems, the kidney should be monitored as

> well.

> >

> > HOWEVER, RSS children are not at risk for liver tumors, or

Wilm's

> > tumors. This is because these tumors are correlated with

> asymmetry

> > when the smaller side is actually the NORMAL side. In cases of

> RSS,

> > the smaller side is the ABNORMAL side, known as hypoplasia of

one

> > limb.

> >

> > Hope this helps!!! Salem