Where do you get OATS test done?

[Guest guest]



Why does one get an OATS test done?

Where do you get them done?

Thanks,

momremb

[Guest guest]

Our doc uses Genova Diagnostics. (Our ins covered most of it). Another option would be Great Plains Lab. If you dont have a doc to order labs, they will hook you up with one (for an additional fee, of course). I believe the price of the lab includes a phone consultation to go over the results.

Tammy

Sent from my Kindle Fire

Sent: Wed Jun 20 13:55:07 EDT 2012

To: mb12valtrex

Subject: Where do you get OATS test done?



Why does one get an OATS test done?

Where do you get them done?

Thanks,

momremb

[Guest guest]

Our doc uses Genova Diagnostics. (Our ins covered most of it). Another option would be Great Plains Lab. If you dont have a doc to order labs, they will hook you up with one (for an additional fee, of course). I believe the price of the lab includes a phone consultation to go over the results.

Tammy

Sent from my Kindle Fire

Sent: Wed Jun 20 13:55:07 EDT 2012

To: mb12valtrex

Subject: Where do you get OATS test done?



Why does one get an OATS test done?

Where do you get them done?

Thanks,

momremb

[Guest guest]

, thank you. So much. As always! I was just bragging about you tonight. It's funny that you popped in with this post.

Tammy

Sent from my Kindle Fire

Sent: Tue Jun 26 19:32:31 EDT 2012

To: mb12valtrex

Subject: Re: Where do you get OATS test done?

Tammy,

The Genova test does not include the oxalate markers, so for this issue of high oxalate, what Genova offers is not a useful test. Neither is Metametrix, though I've talked to them numerous times about adding in this feature, but they won't.

Last September, a group of scientists in Poland (working with me) published a study that is the first one to establish the prevalance of oxalate issues in autism. see: http://www.ncbi.nlm.nih.gov/pubmed/21911305

This study was needed because so many doctors assumed that oxalate being high in autism only represented a " small subgroup " that was probably defined by those with urinary issues. That's why many of these doctors were not seeking this information on their patients or considering that being low oxalate would help in children with autism. Now we know from this study that being high in oxalate is characteristic of the autism population.

I just got back from a trip to Belgium and Germany to go to a meeting of about 65 oxalate scientists.

While over there, in Belgium, I got to visit in the home of a family of one of the first girls with autism to do the low oxalate diet. She had been severely autistic when she was about three, but now, after five or six years of being reduced in oxalate in the diet, this now young teenager has no signs of autism that I could see. She still has some vision problems that she inherited from her dad, but that is unrelated.

She and her ten year old sister on their own prepared for me a gourmet meal with several courses, and a fancy menu. They had done a lot of chopping and artistry making the plates and the table look beautiful and we had several courses with them playing the waiter.

They greeted me with a lot of laughter, and giggles and hugs and playing fun songs on their piano, and showing off their painted fingernails, and other delights. They were very excited to have a guest there to fuss over.

Going low oxalate is not a quick fix, but it is a slow reduction in toxicity. We are still learning a lot of what keeps the oxalate levels from coming down in some people, but overuse of medications seems to be a lot of what does that,as I've seen on people with a series of GPL OATs where they can tell me what their doctor did in between OATs. Problems in oxalate increasing after therapy seems especially an issue with the antimicrobial/antifungal therapies, really opposite of what Great Plains has been saying.

I'm certainly willing to consider that diflucan and nystatin raising oxalate levels may not happen in some people, and for that reason, I am seeking more " before and after " antimicrobial therapy OATs to be sure about the patterns we have seen in this area that have made us concerned. If anyone has before and after GPL OATs when antifungal or antibiotic therapy was used between them, please write me, but realize you cannot see this happening without removing the creatinine correction because raising oxalate can lower everything else on the test, including oxalate.

The Great Plains test does offer three analytes important for spotting the oxalate problem and helping to determine the source of the oxalate. Unfortunately, since oxalate affects the secretion of creatinine, by making secretion from kidney tubule cells unstable, you cannot tell if this huge shift is happening except after the test has gone through new recalculations using a method that gets rid of the already-there correction via creatinine.

I have now analyzed more than 550 of these OATS finding statistical PATTERNS in the amino acid test that are not reported in the writeup of the results that you get from Great Plains.

Labs only look at whether something is above or below a reference range, but there is a lot of information hiding in the changing levels below the reference range, and especially when some things are low but you cannot tell that they are low because the lab gives zero as the bottom of the reference range. I compare you to hundreds of other people and can see when you are abnormally low compared to hundred of other people with a similar diagnosis.

Almosts all urine data is skewed and that is why so many analytes have reference ranges that start with zero. Labs calculate a zero start to the reference range when an analyte's levels are skewed high. When a good chunk of people have high levels on an anlyate, then when the lab calculates two standard deviations below the mean it will take the bottom of the range into numbers that are far below zero, and the labs change that value to zero because people would know something was up if the bottom of the range was a negative number.

Our Polish study, published in the European Journal of Paediatric Neurology, studied only the children who would be assumed to have no risks for being high in oxalate: so they didn't have seizures, they didn't have kidney stones even in their families or kidney issues of their own. They were not on special diets that would increase their oxalate levels, and they hadn't been on antibiotics, etc.

In these children 35 out of 36 children with autism had oxalate levels that did not even overlap at all with control children in both blood and urine, but they were higher than all sixty control children in one of these places, or in both of these compartments where we measure oxalate. This may be one of the most consistent findings ever found in autism.

The one child who overlapped with controls just barely overlapped, but the oxalate levels were so high in most of these children that in a conference I just attended on primary hyperoxaluria (a disease where people die from their bodies making too much oxalate) I had scientists noticing how high the levels were in the study and wondering why the children with autism who had these levels were still alive. That's what they said to me when they saw the data.

Our autism doctors don't realize how extremely high these levels are, especially to professionals in the oxalate field. Many doctors also don't know how toxic oxalate is in general, and don't warn people about spinach and almond milk, and quinoa and amaranth, and buckwheat and chocolate.

So, if you want information about oxalate in your child, don't use the Genova test, but use the test from Great Plains. Nataf's lab also measures oxalate on their organic acid test but I don't have enough of their test to do the urine correction. As far as I know, Great Plains and Nataf's lab (and maybe the European Laboratory) are the only ones who can give you this information . You can order an oxalate only test from Labcorp or Quest that only measures oxalate but it cannot give you the context for it being high.

A DAN! doctor recently sent me repeat tests on three children collecting pee every time they peed on the same day, and the levels of oxalate and creatinine bounced all over the place. The standard in the oxalate field is to use 24 hour tests when you measure oxalate by itself.

>

> Our doc uses Genova Diagnostics. (Our ins covered most of it). Another option would be Great Plains Lab. If you dont have a doc to order labs, they will hook you up with one (for an additional fee, of course). I believe the price of the lab includes a phone consultation to go over the results.

>

> Tammy

>

> Sent from my Kindle Fire

>

[Guest guest]

, thank you. So much. As always! I was just bragging about you tonight. It's funny that you popped in with this post.

Tammy

Sent from my Kindle Fire

Sent: Tue Jun 26 19:32:31 EDT 2012

To: mb12valtrex

Subject: Re: Where do you get OATS test done?

Tammy,

The Genova test does not include the oxalate markers, so for this issue of high oxalate, what Genova offers is not a useful test. Neither is Metametrix, though I've talked to them numerous times about adding in this feature, but they won't.

Last September, a group of scientists in Poland (working with me) published a study that is the first one to establish the prevalance of oxalate issues in autism. see: http://www.ncbi.nlm.nih.gov/pubmed/21911305

This study was needed because so many doctors assumed that oxalate being high in autism only represented a " small subgroup " that was probably defined by those with urinary issues. That's why many of these doctors were not seeking this information on their patients or considering that being low oxalate would help in children with autism. Now we know from this study that being high in oxalate is characteristic of the autism population.

I just got back from a trip to Belgium and Germany to go to a meeting of about 65 oxalate scientists.

While over there, in Belgium, I got to visit in the home of a family of one of the first girls with autism to do the low oxalate diet. She had been severely autistic when she was about three, but now, after five or six years of being reduced in oxalate in the diet, this now young teenager has no signs of autism that I could see. She still has some vision problems that she inherited from her dad, but that is unrelated.

She and her ten year old sister on their own prepared for me a gourmet meal with several courses, and a fancy menu. They had done a lot of chopping and artistry making the plates and the table look beautiful and we had several courses with them playing the waiter.

They greeted me with a lot of laughter, and giggles and hugs and playing fun songs on their piano, and showing off their painted fingernails, and other delights. They were very excited to have a guest there to fuss over.

Going low oxalate is not a quick fix, but it is a slow reduction in toxicity. We are still learning a lot of what keeps the oxalate levels from coming down in some people, but overuse of medications seems to be a lot of what does that,as I've seen on people with a series of GPL OATs where they can tell me what their doctor did in between OATs. Problems in oxalate increasing after therapy seems especially an issue with the antimicrobial/antifungal therapies, really opposite of what Great Plains has been saying.

I'm certainly willing to consider that diflucan and nystatin raising oxalate levels may not happen in some people, and for that reason, I am seeking more " before and after " antimicrobial therapy OATs to be sure about the patterns we have seen in this area that have made us concerned. If anyone has before and after GPL OATs when antifungal or antibiotic therapy was used between them, please write me, but realize you cannot see this happening without removing the creatinine correction because raising oxalate can lower everything else on the test, including oxalate.

The Great Plains test does offer three analytes important for spotting the oxalate problem and helping to determine the source of the oxalate. Unfortunately, since oxalate affects the secretion of creatinine, by making secretion from kidney tubule cells unstable, you cannot tell if this huge shift is happening except after the test has gone through new recalculations using a method that gets rid of the already-there correction via creatinine.

I have now analyzed more than 550 of these OATS finding statistical PATTERNS in the amino acid test that are not reported in the writeup of the results that you get from Great Plains.

Labs only look at whether something is above or below a reference range, but there is a lot of information hiding in the changing levels below the reference range, and especially when some things are low but you cannot tell that they are low because the lab gives zero as the bottom of the reference range. I compare you to hundreds of other people and can see when you are abnormally low compared to hundred of other people with a similar diagnosis.

Almosts all urine data is skewed and that is why so many analytes have reference ranges that start with zero. Labs calculate a zero start to the reference range when an analyte's levels are skewed high. When a good chunk of people have high levels on an anlyate, then when the lab calculates two standard deviations below the mean it will take the bottom of the range into numbers that are far below zero, and the labs change that value to zero because people would know something was up if the bottom of the range was a negative number.

Our Polish study, published in the European Journal of Paediatric Neurology, studied only the children who would be assumed to have no risks for being high in oxalate: so they didn't have seizures, they didn't have kidney stones even in their families or kidney issues of their own. They were not on special diets that would increase their oxalate levels, and they hadn't been on antibiotics, etc.

In these children 35 out of 36 children with autism had oxalate levels that did not even overlap at all with control children in both blood and urine, but they were higher than all sixty control children in one of these places, or in both of these compartments where we measure oxalate. This may be one of the most consistent findings ever found in autism.

The one child who overlapped with controls just barely overlapped, but the oxalate levels were so high in most of these children that in a conference I just attended on primary hyperoxaluria (a disease where people die from their bodies making too much oxalate) I had scientists noticing how high the levels were in the study and wondering why the children with autism who had these levels were still alive. That's what they said to me when they saw the data.

Our autism doctors don't realize how extremely high these levels are, especially to professionals in the oxalate field. Many doctors also don't know how toxic oxalate is in general, and don't warn people about spinach and almond milk, and quinoa and amaranth, and buckwheat and chocolate.

So, if you want information about oxalate in your child, don't use the Genova test, but use the test from Great Plains. Nataf's lab also measures oxalate on their organic acid test but I don't have enough of their test to do the urine correction. As far as I know, Great Plains and Nataf's lab (and maybe the European Laboratory) are the only ones who can give you this information . You can order an oxalate only test from Labcorp or Quest that only measures oxalate but it cannot give you the context for it being high.

A DAN! doctor recently sent me repeat tests on three children collecting pee every time they peed on the same day, and the levels of oxalate and creatinine bounced all over the place. The standard in the oxalate field is to use 24 hour tests when you measure oxalate by itself.

>

> Our doc uses Genova Diagnostics. (Our ins covered most of it). Another option would be Great Plains Lab. If you dont have a doc to order labs, they will hook you up with one (for an additional fee, of course). I believe the price of the lab includes a phone consultation to go over the results.

>

> Tammy

>

> Sent from my Kindle Fire

>