Guest guest Posted May 30, 2005 Report Share Posted May 30, 2005 Dear Phil, You asked whether it was known that Crohn's could cause pancreatitis, and I wanted to tell you that there have been documented cases where this has happened. Upon research, this is what I've found: Crohn's disease is a chronic, inflammatory disease that typically involves the small and/or large intestine. However, some Crohn's patients experience symptoms not directly related to the bowel. These can include skin rashes, joint inflammation and arthritis, eye inflammation, hepatitis (liver inflammation) and bile-duct inflammation. It is unknown why these organs, which are not in direct contact with the bowel, are affected. To answer your question, the pancreas is only very rarely directly affected by Crohn's disease. However, it is not uncommon for pancreatitis (inflammation of the pancreas) to arise as a secondary result of Crohn's. If Crohn's involves the upper small bowel, or duodenum, the inflammatory process can extend to the opening of the duct that drains the pancreas. Inflammation at this opening, called the sphincter of Oddi, can lead to obstruction and pressure on the pancreas, resulting in pancreatitis. In addition, inflammation of the sphincter can result in scarring that leaves the duct open to the intestinal contents found in the duodenum. Reflux of these contents into the pancreatic duct is also hypothesized to cause pancreatitis. It is also known that the medications used to treat Crohn's have caused reactions that lead to pancreatitis. Those medications such as sulfasalozine, mesalamine, azathioprine and 6MP have caused pancreatitis when taken by Crohn's patients. There's also documentation that steriods, such as prednisone, can lead to pancreatitis. You need to understand that some patients with pancreatitis don't experience the typical symptoms early in the course of the disease. There are some who seldom have any pain or discomfort, and others who have few initial symptoms initially, until the condition progresses. Pancreatitis, being progressive in nature, doesn't always start with intense pain, vomiting and nausea, but the symptoms build up in intensity over a gradual period of time until they become consistently noticable. I'm not saying that a lipase reading of 600 is only indicative of pancreatitis, though. There could have been other reasons for such a high count, but with Crohn's already established, it is not unreasonable to presume that the high lipase elevation indicates pancreatitis. You should ask your doctor if he would order other testing to verify this diagnosis. I would assume that your doctor already plans to do this, but that may be a silly assumption on my part. If it were me, I would want further documentation or proof that I did, in fact, have pancreatitis, and would ask for further testing to verify this. You should also ask your doctor what treatment he recommends to treat your pancreatitis; whether he plans to put you on pancreatic enzymes to help with your digestive issues, and what other plans are in the future? Please let us know if there's anything we can do to help you. A low fat, low protein, high carb diet is recommended for pancreatitis patients, and total abstinence from alcohol is also a very necessary adjustment. We'll try to answer any questions you should have about this, or anything else, the best we can. With love, hope and prayers, Heidi Heidi H. Griffeth www.pancassociation.org/anthology#Heidi.html Bluffton, SC SC State & SE Regional Representative Pancreatitis Association, International www.health.groups.yahoo.com/group/pancreatitis/ Note: All comments or advice are personal opinion only, and should not be substituted for professional medical consultation. Quote Link to comment Share on other sites More sharing options...
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