Guest guest Posted July 21, 2007 Report Share Posted July 21, 2007 Hi everyone, I note that there have been some queries about killing off hardy gut bugs, and I have been looking at alternatives to antibiotics. I have done some preliminary enquiries into phage therapy, which I think on this site might be a step too far for some people to embrace. I really do not want to offend anyone, so please, please, please read this with an open mind, I just feel that I have to get this off my chest, and I don't know who else to inform, who would be generous enough in mind to do their own research and be objective about this subject. So here goes. Deep breath people! Phages are viruses. There, I said it. However they are extremely specific in that they only target specific pathogens, and bacteria. They inject their host (pathogens) and more phages grow inside, causing the pathogen to lyse (burst) and release more phages to target and lyse the remaining pathogen until none remain. Then the phages themselves die. They do not harm other, healthy bacteria, unlike antibiotics, or harm human tissue. They are used in Russia, where there is a clinic, and phage cocktails are made up to the specific need of the individual. More info about phages can be found at Wikipedia, where it states " they tend to be more successful where there is a biofilm covered by a polysaccharide layer that antibiotics cannot penetrate " . I know biofilms have been discussed here, so I was immediately interested. I e-mailed a guy a little while ago, informing him of the gut bug connection to autism and various gut conditions, and asked him whether a cocktail could be made based on a stool analysis, if an overgrowth of pathogens were present. He saw no problem with this, but admitted he had not heard of it being used to treat autism or gut conditions. He gave me an e-mail address of someone I could contact for further advise, but I have not yet done so. I have googled phage therapy for info, and as far as I can assume, the phages would be sent over from Russia, and could be given orally. What I wondered was - would someone who has some time (lol) look up phage therapy and give me their feedback, pros and cons etc. I should imagine their would be a huge die off for example. I am going to look this therapy up in Pubmed, to see whether there are any studies, and if anyone is interested I could let them know my findings. I would be interested to hear your views on this subject, so look forward to hearing from you. Regards Glynis mam to Jasmine Diagnosed with Kabuki Syndrome NG tube fed Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 21, 2007 Report Share Posted July 21, 2007 This is what they are starting to do with lunchmeats -- coat them with phage spray to prevent listeria. I think the problem with this therapy might be actually identifying all of the problematic strains in the ASD gut. This would not be easy. A stool test would not identify them all. Also how does the phage " die " after the bacteria is gone? Viruses are not alive to begin with, so they cannot/do not die. - Glynis Steele wrote: Hi everyone, I note that there have been some queries about killing off hardy gut bugs, and I have been looking at alternatives to antibiotics. I have done some preliminary enquiries into phage therapy, which I think on this site might be a step too far for some people to embrace. I really do not want to offend anyone, so please, please, please read this with an open mind, I just feel that I have to get this off my chest, and I don't know who else to inform, who would be generous enough in mind to do their own research and be objective about this subject. So here goes. Deep breath people! Phages are viruses. There, I said it. However they are extremely specific in that they only target specific pathogens, and bacteria. They inject their host (pathogens) and more phages grow inside, causing the pathogen to lyse (burst) and release more phages to target and lyse the remaining pathogen until none remain. Then the phages themselves die. They do not harm other, healthy bacteria, unlike antibiotics, or harm human tissue. They are used in Russia, where there is a clinic, and phage cocktails are made up to the specific need of the individual. More info about phages can be found at Wikipedia, where it states " they tend to be more successful where there is a biofilm covered by a polysaccharide layer that antibiotics cannot penetrate " . I know biofilms have been discussed here, so I was immediately interested. I e-mailed a guy a little while ago, informing him of the gut bug connection to autism and various gut conditions, and asked him whether a cocktail could be made based on a stool analysis, if an overgrowth of pathogens were present. He saw no problem with this, but admitted he had not heard of it being used to treat autism or gut conditions. He gave me an e-mail address of someone I could contact for further advise, but I have not yet done so. I have googled phage therapy for info, and as far as I can assume, the phages would be sent over from Russia, and could be given orally. What I wondered was - would someone who has some time (lol) look up phage therapy and give me their feedback, pros and cons etc. I should imagine their would be a huge die off for example. I am going to look this therapy up in Pubmed, to see whether there are any studies, and if anyone is interested I could let them know my findings. I would be interested to hear your views on this subject, so look forward to hearing from you. Regards Glynis mam to Jasmine Diagnosed with Kabuki Syndrome NG tube fed --------------------------------- Park yourself in front of a world of choices in alternative vehicles. Visit the Yahoo! Auto Green Center. Quote Link to comment Share on other sites More sharing options...
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