Update and question about dark under eye circles/Re: Need Help Finding Problem

July 21, 2007

Thanks Sheila. Your advice is always so helpful. It is nice to have

someone there to reassure and guide! :-)

I think it was the folinic acid/B12. We stopped it for one day and the

circles got better, we tried it again the next, and bam, the shiners

were back. The odd thing is that I know it is SCD legal and even my

" NT " child reacted this way to taking it. Now I'm afraid to take it at

all, but I know we aren't getting hardly any folate in our diet right

now and B12 is on the SCD protocol, so I figured we needed that as

well. I guess I will try to start with less and build up gradually as

you suggested. It is just so odd, we've never had any problems

tolerating legal supplements before this.

In other news, we just tried avocado and I think it went well.

(crossing my fingers). Although it won't become a staple for us

because it is so high in copper, it is nice to have another food that

we can have occasionally. Nice change of pace (and color!) from the

orange carrots and squash, LOL!

Oh and whoever came up with the avocado meatloaf recipe, bravo! My

kids loved it, even my son who hates to eat avocado!!!!

K in Dayton, Ohio

Hashimoto's Thyroiditis, Fibro, CFS, yeast/candida, copper overload,

adrenal fatigue (mostly healed!!!)

Kids: son Rhowan 5 yrs old, chronic diarrhea/loose stools,

yeast/candida, ADHD, salicylate intolerance; daughter Willow 6.5 yrs

old, mild GI issues, salicylate intolerance

Started SCD June 2006, went slightly off for awhile in Nov 2006, back

on strict SCD starting May 2007. (Just redid intro the last week of

June 2007 and are struggling to find tolerated foods)

> To rule out the undripped yogurt as the cause you could go back to

> dripped yogurt for a few days and see if that makes any difference.

>

> If it doesn't it may be caused by the folinic acid with Methyl B12.

> Did you start with a full dose of the folinic acid? If yes, you may

> need to start with less and gradually build up to a full dose.

>

> Sheila, SCD Feb. 2001, UC 23yrs, PCOD 22yrs

> mom of and

>

July 21, 2007

Hi

I think Sheila was suggesting to keep the MB12, but slowly intro the folate

(is that what you were saying Sheila?) If so, I wanted to second that and let

you know our experience with folates in any form. My son has " histadelia " and

cannot take folates (he actually needed anti-folates to bring his levels down

after a short time on them). MB12 helps him a lot, just minus the folates. If

slow introduction does not make it tolerable & your kids fit the description,

you may want to look into this (see below)...

-

HISTADELIA

Individuals with high-histamine levels may be due to a metabolic imbalance

that results from under-methylation. As a consequence, these individuals

overproduce and retain excessive levels of histamine. Histamine is a substance

in the body that has wide ranging effects. There are receptors for histamine in

the brain, stomach, skin, lungs, mucus membranes, blood vessels, etc. For some

individuals, high levels of blood histamine (called histadelia) have

psychological, behavioral, and cognitive symptoms.

Many patients with obsessive-compulsive tendencies, " oppositional-defiant

disorder, " or seasonal depression are under-methylated, which is associated with

low serotonin levels. Often with inhalant allergies, frequent headaches,

perfectionism, competitiveness and other distinctive symptoms and traits. Tend

to be very low in calcium, magnesium, methionine, and vitamin B-6 with excessive

levels of folic acid. People with histadelics have a positive effect from SSRIs

and other serotonin-enhancing medications (Paxil, Zoloft, Prozac, Celexa,

Effexor, etc.) because methylation is a step in the manufacture of mood

stabilizing neurotransmitters. Unfortunately, histadelics often have nasty side

effects with these medications.

Histamine excess can be manifest as asthma, vasomotor rhinitis, allergic skin

disorders with pruritis, excess stomach acid production (acts as a gastric

hormone to stimulate flow of HCl), saliva, tears, and thin nasal and bronchial

secretions, and certain types of vascular headaches. This is the basis of

anti-histamine medications. Excessive histamine results because of the

inadequate methylation in liver detoxification. Histamine opposes adrenalin in

its effects and as expected fatigue occurs just as it occurs in adrenal

exhaustion.

Biochemical treatment revolves around antifolates, especially calcium and

methionine. Certain forms of buffered vitamin C can help by providing calcium

and ascorbic acid. Three to six months of nutrient therapy are usually needed

to correct this chemical imbalance. As in most biochemical therapies, the

symptoms usually return if treatment is stopped.

Methylation is involved in DNA synthesis, masking and unmasking of DNA,

detoxification, heavy mental detoxification, nerve myelination, carnitine and

coenzyme Q 10 synthesis. The relationship of mood and behavior to Histadelia is

due to the fact that methylation is involved in neurotransmitter synthesis.

Source -- http://www.drkaslow.com/html/histadelia.html

Kuykendall wrote: