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CCFA - Novel Inestinal E. Coli linked to Crohns

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Perhaps another medical reason why the SCD works for many of us?

HYPERLINK

" http://www.ccfa.org/reuters/newecoli " http://www.ccfa.org/reuters/newecoli

Novel Intestinal E. Coli Linked to Crohn's Disease

NEW YORK (Reuters Health) Aug 21 -- A selective increase in a novel type of

invasive Escherichia coli relative to depletion of Clostridial species

appears to be involved in the etiology of Crohn's disease, according to a

report in the July 12th issue of the ISME Journal: Multidisciplinary Journal

of Microbial Ecology.

In the study, Dr. W. Simpson, from Cornell University in Ithaca, New

York, and colleagues used DNA analysis to compare the ileal microbial flora

of patients with ileum-involved or colon-only Crohn's disease and of healthy

subjects.

Compared with the other groups, the ileum-involved Crohn's group showed an

increase in E. coli species and decrease in Clostridiales. Moreover, the

severity of the ileitis was directly related to the number of E. coli

present. Lastly, only invasive species of E. coli were found in inflamed

mucosa.

Further analysis showed that the invasive E. coli exhibited novel phylogeny

with characteristics similar to that of extraintestinal pathogenic E. coli

and Enterobacteriaceae.

" Our findings raise the possibility that a novel group of E. coli contains

opportunistic pathogens that may be causally related to chronic intestinal

inflammation in susceptible individuals, " Dr. Simpson said in a statement.

" They suggest that an integrated approach that considers an individual's

mucosa-associated flora in addition to disease phenotype and genotype may

improve outcome. "

Date Posted: August 22, 2007

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Hi,

I got the email also. Do you mean because of the yogurt, it eventually

starves out the ecoli? How would you get tested and/or treated for this?

I emailed ccfa to ask them also.

Thanks for any info, a little technical for me :P

Debbie 38 crohn's

pentasa

scd 1/07

>

> Perhaps another medical reason why the SCD works for many of us?

>

> HYPERLINK

> " http://www.ccfa.org/reuters/newecoli " http://www.ccfa.org/reuters/newecoli

>

> Novel Intestinal E. Coli Linked to Crohn's Disease

>

> NEW YORK (Reuters Health) Aug 21 -- A selective increase in a novel type

> of

> invasive Escherichia coli relative to depletion of Clostridial species

> appears to be involved in the etiology of Crohn's disease, according to a

> report in the July 12th issue of the ISME Journal: Multidisciplinary

> Journal

> of Microbial Ecology.

>

> In the study, Dr. W. Simpson, from Cornell University in Ithaca,

> New

> York, and colleagues used DNA analysis to compare the ileal microbial

> flora

> of patients with ileum-involved or colon-only Crohn's disease and of

> healthy

> subjects.

>

> Compared with the other groups, the ileum-involved Crohn's group showed an

> increase in E. coli species and decrease in Clostridiales. Moreover, the

> severity of the ileitis was directly related to the number of E. coli

> present. Lastly, only invasive species of E. coli were found in inflamed

> mucosa.

>

> Further analysis showed that the invasive E. coli exhibited novel

> phylogeny

> with characteristics similar to that of extraintestinal pathogenic E. coli

> and Enterobacteriaceae.

>

> " Our findings raise the possibility that a novel group of E. coli contains

> opportunistic pathogens that may be causally related to chronic intestinal

> inflammation in susceptible individuals, " Dr. Simpson said in a statement.

> " They suggest that an integrated approach that considers an individual's

> mucosa-associated flora in addition to disease phenotype and genotype may

> improve outcome. "

>

> Date Posted: August 22, 2007

>

> No virus found in this incoming message.

> Checked by AVG Free Edition.

> Version: 7.5.484 / Virus Database: 269.12.2/967 - Release Date: 8/22/2007

> 6:51 PM

>

> No virus found in this outgoing message.

> Checked by AVG Free Edition.

> Version: 7.5.484 / Virus Database: 269.12.2/967 - Release Date: 8/22/2007

> 6:51 PM

>

>

>

>

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Hi JT,

Thank you so much for this info. I am not surprised.

Children with ASD have also been found to have very high levels of E Coli

E. Coli are negative gram bacteria and therefore contain a toxin called LPS.

LPS has been found to cause lots of intestinal damage for those with IBD.

http://microbialinfluence.com/GI.html

LPS causes brain and emotional damage to ASD children.

http://microbialinfluence.com/Emotions.html

http://microbialinfluence.com/Brain.html

LPS can also bring many other diseases, it all depends where there is a

vulnerability

Mimi

============================================================

http://www.ccfa.org/reuters/newecoli " http://www.ccfa.org/reuters/newecoli

Novel Intestinal E. Coli Linked to Crohn's Disease

NEW YORK (Reuters Health) Aug 21 -- A selective increase in a novel type of

invasive Escherichia coli relative to depletion of Clostridial species

appears to be involved in the etiology of Crohn's disease, according to a

report in the July 12th issue of the ISME Journal: Multidisciplinary Journal

of Microbial Ecology.

In the study, Dr. W. Simpson, from Cornell University in Ithaca, New

York, and colleagues used DNA analysis to compare the ileal microbial flora

of patients with ileum-involved or colon-only Crohn's disease and of healthy

subjects.

Compared with the other groups, the ileum-involved Crohn's group showed an

increase in E. coli species and decrease in Clostridiales. Moreover, the

severity of the ileitis was directly related to the number of E. coli

present. Lastly, only invasive species of E. coli were found in inflamed

mucosa.

>

>

>

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Debbie,

The short form of how I translate that is that

the CCFA finally figured out what Dr. Haas knew

around 60 years ago: an imbalance in our gut bugs

is what can make us sick. Treat the imbalance of

the gut bugs (like with SCD!) and the patient is

likely to respond much, much better.

Man, I wish Elaine were alive to see this!

— Marilyn

New Orleans, Louisiana, USA

Undiagnosed IBS since 1976, SCD since 2001

Darn Good SCD Cook

No Human Children

Shadow & Sunny Longhair Dachshund

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Thank you for posting. I think this is wonderful that they are

starting to get closer to understanding the causes of these

inflammatory conditions. To me it seems a little strange to learn

that they are just now thinking " hey - maybe we should figure out

which baddie is causing what and then treat THAT! " I know that's not

really how it is; they have suspected various things but need to

utilize the scientific method which can only go so far on hunches.

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You are welcome. And thank you! :-)

No virus found in this incoming message.

Checked by AVG Free Edition.

Version: 7.5.484 / Virus Database: 269.12.2/967 - Release Date: 8/22/2007

6:51 PM

No virus found in this outgoing message.

Checked by AVG Free Edition.

Version: 7.5.484 / Virus Database: 269.12.4/969 - Release Date: 8/23/2007

4:04 PM

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