Guest guest Posted October 25, 2005 Report Share Posted October 25, 2005 I picked this up on the internet this evening. Just thought I'd share. Jerry/NC ******************************************************** *FDA Broadens Liver Warning for Cymbalta*** *Patients With Liver Disease May Risk Further Liver Damage, Says FDA*** Oct. 17, 2005 -- The FDA and Eli Lilly and Co. have broadened a warning about possible liver problems with Cymbalta, a drug used to treat depression and pain associated with diabetic peripheral neuropathy. " Postmarketing reports of liver injury (including hepatitis and cholestatic jaundice) suggest that patients with pre-existing liver disease who take [Cymbalta] may have an increased risk for further liver damage, " says the FDA. Cymbalta's labeling previously noted possible liver problems. The label had warned that " Cymbalta should ordinarily not be prescribed to patients with substantial alcohol use. " Now, that warning will read, " Cymbalta should ordinarily not be prescribed to patients with substantial alcohol use or evidence of chronic liver disease, " according to a letter to doctors sent by Lilly, Cymbalta's maker. " It is recommended that Cymbalta not be administered to patients with any [liver] insufficiency, " says the FDA. *Maker's Letter to Doctors* About a million people have taken Cymbalta since the drug's approval in 2004, according to Lilly's letter. " Among these, several cases of [liver] injury have been spontaneously reported, " states Lilly's letter. " Some of these patients had underlying liver disease. Review of these cases suggests that patients with underlying chronic liver disease may be at increased risk of [liver] toxicity with [Cymbalta], " the letter continues. Lilly is a WebMD sponsor. *Symptoms* Signs and symptoms of liver damage can include dark urine, jaundice (yellowing of the skin and eyes), itchiness, abdominal tenderness in the liver area, or unexplained flu-like symptoms. Elevations of liver enzymes may be found on blood tests. Lilly asks that any questions about the warning be directed to Lilly's medical department at (800) Lilly-Rx (). Report any Cymbalta side effects to Lilly at (800) Lilly-Rx () or to the FDA's Medwatch program at (800) FDA-1088 () or online at www.fda.gov/medwatch <http://www.fda.gov/medwatch>. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 25, 2005 Report Share Posted October 25, 2005 -Jerry thanks for the info. I was on this for one month. I am glad that my insurance did not cover it. It did make me feel good at the beginning then really bad toward the end of the month. Flu type symptoms. I am glad is was only on it for a month! Walt Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 26, 2005 Report Share Posted October 26, 2005 I have been a member of this group for a while. I rarely post, but I would like to say that I am on Cymbalta 60mgs. I take it at night so that I don't feel any of the side effects of the medicine. It has helped me tremendously. I have had a whipple and many other operations. Every day was such a struggle for me until I started the Cymbalta. I know that many people have trouble taking it, I must be an exception. For me, I pray they don't take it off the market. I guess what I want to get across is, that may be the medicine may be not right for you, but for me or others, would have more pain if the medicine is taken off the market. Stay well all Paget Quote Link to comment Share on other sites More sharing options...
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