Guest guest Posted December 19, 2012 Report Share Posted December 19, 2012 Bonnie - My guess would be that you are not methylating well. So, your body builds up the b-12 because it isn't converting it to the methylated form. Taking mb-12 is a good solution until you can improve your methylation. And, you probably have some genetic predisposition to certain pathways (like MTHFR) that are causing the problem. Here is some information on methylation. http://www.holisticheal.com/media/downloads/guide-to-nutrigenomic-testing.pdfHope that helps.RuthSent from my iPad Hello: My first posting. I hope I have joined the right list. I’ve been recently (almost a year) taking 1,000 mcg. of sublingual Methylcobalmin. A recent blood test showed Vitamin B12 = 1475 (198 – 680) MCV = 97 (80 - -96) I have called the doctor’s office for two weeks now to find out what this means. I’m thinking I have Macrocytosis but how could I be anemic with a B12 so high? Thanks for any direction. Thanks, Bonnie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 19, 2012 Report Share Posted December 19, 2012 Ruth: Thank you so much for this reply. I guess I did join the right list. Not converting makes sense, but I thought my blood level would be high, simply because I was taking Methylcobalamin sublingually, so there would be no need to CONVERT IT, right? If it is already in that form, it shouldn’t need converting. Have I got that wrong? Thanks, Bonnie From: mb12valtrex [mailto:mb12valtrex ] On Behalf Of Ruth Setlak Sent: Wednesday, December 19, 2012 8:01 PM To: mb12valtrex Subject: Re: a newbie with a question Bonnie - My guess would be that you are not methylating well. So, your body builds up the b-12 because it isn't converting it to the methylated form. Taking mb-12 is a good solution until you can improve your methylation. And, you probably have some genetic predisposition to certain pathways (like MTHFR) that are causing the problem. Here is some information on methylation. http://www.holisticheal.com/media/downloads/guide-to-nutrigenomic-testing.pdf Hope that helps. Ruth Sent from my iPad Hello: My first posting. I hope I have joined the right list. I’ve been recently (almost a year) taking 1,000 mcg. of sublingual Methylcobalmin. A recent blood test showed Vitamin B12 = 1475 (198 – 680) MCV = 97 (80 - -96) I have called the doctor’s office for two weeks now to find out what this means. I’m thinking I have Macrocytosis but how could I be anemic with a B12 so high? Thanks for any direction. Thanks, Bonnie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 19, 2012 Report Share Posted December 19, 2012 No. You are right in that you are skipping that step in the pathway. That will help. Ultimately you would want to fix whatever is impeding gulag way from working correctly. This could be an infection, a toxin, a nutrient deficiency etc. then your body can use the b-12, convert it, and so on. RuthSent from my iPhone Ruth: Thank you so much for this reply. I guess I did join the right list. Not converting makes sense, but I thought my blood level would be high, simply because I was taking Methylcobalamin sublingually, so there would be no need to CONVERT IT, right? If it is already in that form, it shouldn’t need converting. Have I got that wrong? Thanks, Bonnie From: mb12valtrex [mailto:mb12valtrex ] On Behalf Of Ruth Setlak Sent: Wednesday, December 19, 2012 8:01 PM To: mb12valtrex Subject: Re: a newbie with a question Bonnie - My guess would be that you are not methylating well. So, your body builds up the b-12 because it isn't converting it to the methylated form. Taking mb-12 is a good solution until you can improve your methylation. And, you probably have some genetic predisposition to certain pathways (like MTHFR) that are causing the problem. Here is some information on methylation. http://www.holisticheal.com/media/downloads/guide-to-nutrigenomic-testing.pdf Hope that helps. Ruth Sent from my iPad Hello: My first posting. I hope I have joined the right list. I’ve been recently (almost a year) taking 1,000 mcg. of sublingual Methylcobalmin. A recent blood test showed Vitamin B12 = 1475 (198 – 680) MCV = 97 (80 - -96) I have called the doctor’s office for two weeks now to find out what this means. I’m thinking I have Macrocytosis but how could I be anemic with a B12 so high? Thanks for any direction. Thanks, Bonnie Quote Link to comment Share on other sites More sharing options...
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