Guest guest Posted October 29, 2008 Report Share Posted October 29, 2008 Dear Ali, While DMPS and DMSA are useful for some people suppressing symptoms, these chelators cannot cross the blood-brain barrier nor reach the intracellular spaces. To clean the brain and organs you need to use ALA. It is the main and essential chelator. While DMPS and DMSA only increase natural mercury excretion a little bit (about 30%), ALA increases mercury excretion a lot (in animal studies, from 1200% to 2700%). It is not worth to pay huge amounts of money to get DMPS or DMSA, not to tell about assuming risks using dubious quality DMPS! If you have no economical problems, you may want to get some DMSA or DMPS to see if ALA chelation is smoother when adding it. But a lot of people do well using ALA only. It is so amazing that the main chelator is so cheap! As pointed out before by , it seems unavoidable to wake up several times at night to take our ALA if we want to get well, independently of whether you are using it along with DMSA/DMPS or not. It is not so bad when you get used to it! Good luck! > > Thank you everybody for answering. > > Ok. So I understand that getting DMPS without > prescription is impossible in the US. > > Is it possible for a US doctor to prescribe me > DMPS which can then be sent to me in the Netherlands? > > Does anybody know such a doctor which prescribes > DMPS? I can't come to the US unfortunately. Maybe > online consultation or something? > > Anybody know how much this might cost? All the supps > I am using are already quite expensive, but what can I > do. I must pay to get healthy. > > I will email the New Zealand pharmacy. Let you guys > know if they will compound and ship internationally > without prescription. > > Thanks in advance for help/advise. > > Greetings, > > Ali > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 31, 2008 Report Share Posted October 31, 2008 > > DMPS is not the option of choice for copper. See > http://onibasu.com/archives/am/19480.html. > > > > If you are correct in that ALA increases mercury excretion by 1200% > > and DMPS only 30%, that means that using ALA for a round is the same > > as using DMPS for 40 rounds or so. I don't think this is correct > > . > > Please read Amalgam Illness and Hair Test Interpretation, you will > find there lots of information useful for you. Check AI, p. 202. The > figures for increasing of bile mercury excretion using ALA are found > in Gregus et al., " Effect of lipoic acid on biliary excretion of > glutathione and metals " , Toxicology and Applied Pharmacology, Volume > 114, Issue 1, May 1992, Pages 88-96 . > > > > > I don't think people would use DMPS if it would excrete so little > > mercury. > > There two good reasons to use DMPS are symptom suppression and faster > clearance of blood mercury, for example after amalgam removal. > > Hope you will find your way to get better. > Good luck! > > > Thank you for your advise . I am already taking high dosage zinc everyday for copper detox. Here is an abstract on how DMPS increases copper and mercury excretion: ''Urinary excretion of trace elements in humans after sodium 2,3-dimercaptopropane-1-sulfonate challenge test. -Alanís O, Garza-Ocañas L, Bernal MA, Piñeyro-López A. Centro Antivenenos, Departamento de Farmacología y Toxicología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey Nuevo León, México. otorres@... OBJECTIVE: To evaluate the effects of intravenous sodium 2,3-dimercaptopropane-1-sulfonate (DMPS, Dimaval) on urinary excretion of essential trace elements in subjects who received this chelating agent as a mercury challenge test. SUBJECTS: Eleven subjects sought medical attention due to concern with the toxicity of mercury released from dental amalgam fillings. DESIGN: The subjects were given DMPS 3 mg/kg intravenously. Spot urine samples were collected 1 hour before and 1 hour after the DMPS dose for laboratory analysis. In addition to mercury, the urinary excretion of copper, zinc, selenium, magnesium, manganese, molybdenum, chromium, cobalt, and aluminum were measured. RESULTS: A significant increase in urinary excretion of mercury (3- to 107-fold) was observed after the DMPS dose. The DMPS treatment led to a 2- to 119-fold increase in copper excretion; 3- to 43.8-fold in selenium excretion; 1.6- to 44-fold in zinc excretion; and 1.75- to 42.7-fold in magnesium excretion. The excretion of manganese, chromium, cobalt, aluminium, and molybdenum remained unchanged. CONCLUSIONS: In this study, an intravenous DMPS challenge test produced a significant increase in mercury excretion and also led to an increased excretion of copper, selenium, zinc, and magnesium. http://www.ncbi.nlm.nih.gov/pubmed/11192456?ordinalpos=16 & itool=EntrezSystem2.PE\ ntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum'' From reading this abstract I would assume that DMPS increases excretion of copper and mercury substantially in the urine. Greetings, Ali Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 31, 2008 Report Share Posted October 31, 2008 Ali, If you read the abstract carefully you will notice that the mercury in urine is increased *significantly* (that means they used statistics to test and see if there was a significant increase). The increases reported for other elements were *not significant* (that means that any increase could be due to chance or experimental error because it didn't pass any statistical tests). This paper actually supports the hypothesis that mercury is chelated out selectively by DMPS and not the other elements tested, to any significant extent. When checking to see what really happens in humans one would want to look at all of the literature and cull out the papers where there was something wrong with how they did things. > > Thank you for your advise . > > I am already taking high dosage zinc everyday for copper detox. > > Here is an abstract on how DMPS increases copper and mercury > excretion: > > ''Urinary excretion of trace elements in humans after sodium > 2,3-dimercaptopropane-1-sulfonate challenge test. > -Alanís O, Garza-Ocañas L, Bernal MA, Piñeyro-López A. > > Centro Antivenenos, Departamento de Farmacología y Toxicología, > Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey > Nuevo León, México. otorres@... > > OBJECTIVE: To evaluate the effects of intravenous sodium > 2,3-dimercaptopropane-1-sulfonate (DMPS, Dimaval) on urinary excretion > of essential trace elements in subjects who received this chelating > agent as a mercury challenge test. SUBJECTS: Eleven subjects sought > medical attention due to concern with the toxicity of mercury released > from dental amalgam fillings. DESIGN: The subjects were given DMPS 3 > mg/kg intravenously. Spot urine samples were collected 1 hour before > and 1 hour after the DMPS dose for laboratory analysis. In addition to > mercury, the urinary excretion of copper, zinc, selenium, magnesium, > manganese, molybdenum, chromium, cobalt, and aluminum were measured. > RESULTS: A significant increase in urinary excretion of mercury (3- to > 107-fold) was observed after the DMPS dose. The DMPS treatment led to > a 2- to 119-fold increase in copper excretion; 3- to 43.8-fold in > selenium excretion; 1.6- to 44-fold in zinc excretion; and 1.75- to > 42.7-fold in magnesium excretion. The excretion of manganese, > chromium, cobalt, aluminium, and molybdenum remained unchanged. > CONCLUSIONS: In this study, an intravenous DMPS challenge test > produced a significant increase in mercury excretion and also led to > an increased excretion of copper, selenium, zinc, and magnesium. > > http://www.ncbi.nlm.nih.gov/pubmed/11192456?ordinalpos=16 & itool=EntrezSystem2.PE\ ntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum'' > > From reading this abstract I would assume that DMPS increases > excretion of copper and mercury substantially in the urine. > > > Greetings, > > Ali > Quote Link to comment Share on other sites More sharing options...
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