Guest guest Posted August 22, 2009 Report Share Posted August 22, 2009 Jack, Why were you taking NAC? I didn't know it had anything to do with allergies or GERD. Subject: Re: vitamins and other supplimentsTo: Breathe-Support Date: Friday, August 21, 2009, 1:19 PM NAC did nothing for me, so I quit taking it and have several bottles for anyone who can use them. I have had great success with Zyrtec, which is an OTC for allergies. My theory is that it is effective in controlling runny noses and coughing and that was my problem. After a month, my runny nose had dried up and my coughing was down to a few instances when I am exposed to high humidity or cold. I have been dripless and coughless for six months. I take one a day. Jack79/IPF - UIP/dx06/05 Maine From: drisanamerry <drisanamerry@ yahoo.com>To: Breathe-Support@ yahoogroups. comSent: Thursday, August 20, 2009 2:03:34 PMSubject: vitamins and other suppliments I would be interested in what other vitamins and suppliments you all would suggest be taken.hugsmerryI count not a day complete till needle, thread and fabric do meet.2009 will be mighty fine!Due to recent budget cuts and the rising cost of electricity, gas and oil,as well as current market conditions, the Light at the End of the Tunnel has been turned off. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 22, 2009 Report Share Posted August 22, 2009 I don't have allergies nor gerd. In fact, the only thing I have is IPF and an occassional head ache. I was taking it for cough, but it didn't help. Jack79/IPF - UIP/dx06/05 Maine To: Breathe-Support Sent: Saturday, August 22, 2009 4:42:39 PMSubject: Re: NAC & Zyrtec Jack, Why were you taking NAC? I didn't know it had anything to do with allergies or GERD. From: Jack Marshall <mrshlljck (AT) yahoo (DOT) com>Subject: Re: vitamins and other supplimentsTo: Breathe-Support@ yahoogroups. comDate: Friday, August 21, 2009, 1:19 PM NAC did nothing for me, so I quit taking it and have several bottles for anyone who can use them. I have had great success with Zyrtec, which is an OTC for allergies. My theory is that it is effective in controlling runny noses and coughing and that was my problem. After a month, my runny nose had dried up and my coughing was down to a few instances when I am exposed to high humidity or cold. I have been dripless and coughless for six months. I take one a day. Jack79/IPF - UIP/dx06/05 Maine From: drisanamerry <drisanamerry@ yahoo.com>To: Breathe-Support@ yahoogroups. comSent: Thursday, August 20, 2009 2:03:34 PMSubject: vitamins and other suppliments I would be interested in what other vitamins and suppliments you all would suggest be taken.hugsmerryI count not a day complete till needle, thread and fabric do meet.2009 will be mighty fine!Due to recent budget cuts and the rising cost of electricity, gas and oil,as well as current market conditions, the Light at the End of the Tunnel has been turned off. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 Jack,NAC (Acetylcystein) is not just for cough. It is a liquid chemical that thins fluids in the lungs, produced by the body that enhances the production of the enzyme glutathione, a powerful antioxidant. It helps boost the immune system. NAC is used as mucus dissolving agent to help break up the thick mucus often present in people suffering from chronic respiratory ailments. This medication belongs to a class of drugs called antioxidants. Oxidation is a natural process that leads to cell and tissue damage. The process that may play a role in development of scarring in the lungs (pulmonary fibrosis). Results froma clinical trial found that, when combined with cortocosteroids and azathioprine, NAC improved lung function in (20%) of people with idiopathic pulmonary fibrosis. C_53_Familial IPF_5/09WashingtonTo: Breathe-Support Sent: Saturday, August 22, 2009 2:18:23 PMSubject: Re: NAC & Zyrtec I don't have allergies nor gerd. In fact, the only thing I have is IPF and an occassional head ache. I was taking it for cough, but it didn't help. Jack79/IPF - UIP/dx06/05 Maine From: Adrienne Bishop <eggie5909 (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Saturday, August 22, 2009 4:42:39 PMSubject: Re: NAC & Zyrtec Jack, Why were you taking NAC? I didn't know it had anything to do with allergies or GERD. From: Jack Marshall <mrshlljck (AT) yahoo (DOT) com>Subject: Re: vitamins and other supplimentsTo: Breathe-Support@ yahoogroups. comDate: Friday, August 21, 2009, 1:19 PM NAC did nothing for me, so I quit taking it and have several bottles for anyone who can use them. I have had great success with Zyrtec, which is an OTC for allergies. My theory is that it is effective in controlling runny noses and coughing and that was my problem. After a month, my runny nose had dried up and my coughing was down to a few instances when I am exposed to high humidity or cold. I have been dripless and coughless for six months. I take one a day. Jack79/IPF - UIP/dx06/05 Maine From: drisanamerry <drisanamerry@ yahoo.com>To: Breathe-Support@ yahoogroups. comSent: Thursday, August 20, 2009 2:03:34 PMSubject: vitamins and other suppliments I would be interested in what other vitamins and suppliments you all would suggest be taken.hugsmerryI count not a day complete till needle, thread and fabric do meet.2009 will be mighty fine!Due to recent budget cuts and the rising cost of electricity, gas and oil,as well as current market conditions, the Light at the End of the Tunnel has been turned off. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 , Thanks for clarifying that for Jack. NAC is not a cough suppressant by any means. It's a mucolytic meaning it does just what says, thins mucous making it easier to cough up and out. In this action it does the same thing that the medication in Mucinex does. If you don't have alot of mucous it's not going to make any kind of perceptable difference in the cough. It is as mentioned a very powerful anti-oxidant. One thing that Dr. Simonelli in NY had told me that though he didn't really believe NAC would do anything useful for my lungs he wanted me to take it for as long as I was on the prednisone. He felt rather strongly that the NAC could help prevent some of the more serious prednisone side effects. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 To: Breathe-Support Sent: Sunday, August 23, 2009 12:34:07 PMSubject: Re: NAC & Zyrtec Jack,NAC (Acetylcystein) is not just for cough. It is a liquid chemical that thins fluids in the lungs, produced by the body that enhances the production of the enzyme glutathione, a powerful antioxidant. It helps boost the immune system. NAC is used as mucus dissolving agent to help break up the thick mucus often present in people suffering from chronic respiratory ailments. This medication belongs to a class of drugs called antioxidants. Oxidation is a natural process that leads to cell and tissue damage. The process that may play a role in development of scarring in the lungs (pulmonary fibrosis). Results froma clinical trial found that, when combined with cortocosteroids and azathioprine, NAC improved lung function in (20%) of people with idiopathic pulmonary fibrosis. C_53_Familial IPF_5/09Washington From: Jack Marshall <mrshlljck (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Saturday, August 22, 2009 2:18:23 PMSubject: Re: NAC & Zyrtec I don't have allergies nor gerd. In fact, the only thing I have is IPF and an occassional head ache. I was taking it for cough, but it didn't help. Jack79/IPF - UIP/dx06/05 Maine From: Adrienne Bishop <eggie5909 (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Saturday, August 22, 2009 4:42:39 PMSubject: Re: NAC & Zyrtec Jack, Why were you taking NAC? I didn't know it had anything to do with allergies or GERD. From: Jack Marshall <mrshlljck (AT) yahoo (DOT) com>Subject: Re: vitamins and other supplimentsTo: Breathe-Support@ yahoogroups. comDate: Friday, August 21, 2009, 1:19 PM NAC did nothing for me, so I quit taking it and have several bottles for anyone who can use them. I have had great success with Zyrtec, which is an OTC for allergies. My theory is that it is effective in controlling runny noses and coughing and that was my problem. After a month, my runny nose had dried up and my coughing was down to a few instances when I am exposed to high humidity or cold. I have been dripless and coughless for six months. I take one a day. Jack79/IPF - UIP/dx06/05 Maine From: drisanamerry <drisanamerry@ yahoo.com>To: Breathe-Support@ yahoogroups. comSent: Thursday, August 20, 2009 2:03:34 PMSubject: vitamins and other suppliments I would be interested in what other vitamins and suppliments you all would suggest be taken.hugsmerryI count not a day complete till needle, thread and fabric do meet.2009 will be mighty fine!Due to recent budget cuts and the rising cost of electricity, gas and oil,as well as current market conditions, the Light at the End of the Tunnel has been turned off. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 , That information you gave Jack was quite helpful for me. I wondered what the real benefits of taking NAC were despite what my doctor said. Between your info and what Beth said about the interaction with Prednisone it has made things a bit clearer for me. Thanks, Adrienne From: Jack Marshall <mrshlljck (AT) yahoo (DOT) com>Subject: Re: vitamins and other supplimentsTo: Breathe-Support@ yahoogroups. comDate: Friday, August 21, 2009, 1:19 PM NAC did nothing for me, so I quit taking it and have several bottles for anyone who can use them. I have had great success with Zyrtec, which is an OTC for allergies. My theory is that it is effective in controlling runny noses and coughing and that was my problem. After a month, my runny nose had dried up and my coughing was down to a few instances when I am exposed to high humidity or cold. I have been dripless and coughless for six months. I take one a day. Jack79/IPF - UIP/dx06/05 Maine From: drisanamerry <drisanamerry@ yahoo.com>To: Breathe-Support@ yahoogroups. comSent: Thursday, August 20, 2009 2:03:34 PMSubject: vitamins and other suppliments I would be interested in what other vitamins and suppliments you all would suggest be taken.hugsmerryI count not a day complete till needle, thread and fabric do meet.2009 will be mighty fine!Due to recent budget cuts and the rising cost of electricity, gas and oil,as well as current market conditions, the Light at the End of the Tunnel has been turned off. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 Thanks, , for that information. I was unaware of it. My NAC are capsules. I do have a nubulizer but have not yet used it. I'll give it a try this winter. Jack79/IPF - UIP/dx06/05 Maine To: Breathe-Support Sent: Sunday, August 23, 2009 12:34:07 PMSubject: Re: NAC & Zyrtec Jack,NAC (Acetylcystein) is not just for cough. It is a liquid chemical that thins fluids in the lungs, produced by the body that enhances the production of the enzyme glutathione, a powerful antioxidant. It helps boost the immune system. NAC is used as mucus dissolving agent to help break up the thick mucus often present in people suffering from chronic respiratory ailments. This medication belongs to a class of drugs called antioxidants. Oxidation is a natural process that leads to cell and tissue damage. The process that may play a role in development of scarring in the lungs (pulmonary fibrosis). Results froma clinical trial found that, when combined with cortocosteroids and azathioprine, NAC improved lung function in (20%) of people with idiopathic pulmonary fibrosis. C_53_Familial IPF_5/09Washington From: Jack Marshall <mrshlljck (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Saturday, August 22, 2009 2:18:23 PMSubject: Re: NAC & Zyrtec I don't have allergies nor gerd. In fact, the only thing I have is IPF and an occassional head ache. I was taking it for cough, but it didn't help. Jack79/IPF - UIP/dx06/05 Maine From: Adrienne Bishop <eggie5909 (AT) yahoo (DOT) com>To: Breathe-Support@ yahoogroups. comSent: Saturday, August 22, 2009 4:42:39 PMSubject: Re: NAC & Zyrtec Jack, Why were you taking NAC? I didn't know it had anything to do with allergies or GERD. From: Jack Marshall <mrshlljck (AT) yahoo (DOT) com>Subject: Re: vitamins and other supplimentsTo: Breathe-Support@ yahoogroups. comDate: Friday, August 21, 2009, 1:19 PM NAC did nothing for me, so I quit taking it and have several bottles for anyone who can use them. I have had great success with Zyrtec, which is an OTC for allergies. My theory is that it is effective in controlling runny noses and coughing and that was my problem. After a month, my runny nose had dried up and my coughing was down to a few instances when I am exposed to high humidity or cold. I have been dripless and coughless for six months. I take one a day. Jack79/IPF - UIP/dx06/05 Maine From: drisanamerry <drisanamerry@ yahoo.com>To: Breathe-Support@ yahoogroups. comSent: Thursday, August 20, 2009 2:03:34 PMSubject: vitamins and other suppliments I would be interested in what other vitamins and suppliments you all would suggest be taken.hugsmerryI count not a day complete till needle, thread and fabric do meet.2009 will be mighty fine!Due to recent budget cuts and the rising cost of electricity, gas and oil,as well as current market conditions, the Light at the End of the Tunnel has been turned off. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 To my knowledge though no trials have been completed yet and published. Dr. Raghu may have observations from what he's seen in his portion or discussions with colleagues. I do believe NAC helps many. But the trials are underway. In fact these are the first trials for prednisone as well. > > > >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com> > >Subject: Re: vitamins and other suppliments > >To: Breathe-Support@ yahoogroups. com > >Date: Friday, August 21, 2009, 1:19 PM > > > > > > > >NAC did nothing for me, so I quit taking it and have several bottles for anyone who can use them. I have had great success with Zyrtec, which is an OTC for allergies. My theory is that it is effective in controlling runny noses and coughing and that was my problem. After a month, my runny nose had dried up and my coughing was down to a few instances when I am exposed to high humidity or cold. I have been dripless and coughless for six months. I take one a day. > > > > Jack > >79/IPF - UIP/dx06/05 Maine > > > > > > > > > > > ________________________________ > From: drisanamerry <drisanamerry@ yahoo.com> > >To: Breathe-Support@ yahoogroups. com > >Sent: Thursday, August 20, 2009 2:03:34 PM > >Subject: vitamins and other suppliments > > > > > >I would be interested in what other vitamins and suppliments you all would suggest be taken. > > > >hugs > > > >merry > > > >I count not a day complete till needle, thread and fabric do meet. > >2009 will be mighty fine! > >Due to recent budget cuts and the rising cost of electricity, gas and oil, > >as well as current market conditions, the Light at the End of the Tunnel has been turned off. > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 Bruce, I haven't seen any published studies yet either. The Panther Trials (Prednisone, Imuran and NAC) are just getting underway and the results are a ways off yet to the best of my knowledge. I am immensely curious about how it will all turn out. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 To: Breathe-Support Sent: Sunday, August 23, 2009 4:19:28 PMSubject: Re: NAC & Zyrtec To my knowledge though no trials have been completed yet and published.Dr. Raghu may have observations from what he's seen in his portion ordiscussions with colleagues. I do believe NAC helps many. But the trialsare underway. In fact these are the first trials for prednisone as well.>>> >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com>> >Subject: Re: vitamins and other suppliments> >To: Breathe-Support@ yahoogroups. com> >Date: Friday, August 21, 2009, 1:19 PM> >> >> >> >NAC did nothing for me, so I quit taking it and have several bottlesfor anyone who can use them. I have had great success with Zyrtec,which is an OTC for allergies. My theory is that it is effective incontrolling runny noses and coughing and that was my problem. After amonth, my runny nose had dried up and my coughing was down to a fewinstances when I am exposed to high humidity or cold. I have beendripless and coughless for six months. I take one a day.> >> > Jack> >79/IPF - UIP/dx06/05 Maine> >> >> >> >> >> ____________ _________ _________ __> From: drisanamerry <drisanamerry@ yahoo.com>> >To: Breathe-Support@ yahoogroups. com> >Sent: Thursday, August 20, 2009 2:03:34 PM> >Subject: vitamins and other suppliments> >> >> >I would be interested in what other vitamins and suppliments you allwould suggest be taken.> >> >hugs> >> >merry> >> >I count not a day complete till needle, thread and fabric do meet.> >2009 will be mighty fine!> >Due to recent budget cuts and the rising cost of electricity, gas andoil,> >as well as current market conditions, the Light at the End of theTunnel has been turned off.> >> >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 From what I have gathered thus far, the animal models have shown reduction in inflamation following induced fibrosis-causing agent with inhaled NAC. And from these studies it has been assumed that human models will react similarly. Although I don't notice any appreciable difference when I don't take NAC, I feel better knowing that it isn't hurting, and most studies support using it. However, in a study of Glutathion by way of an aerosol, it was found that PFT results showed a marked reduction in lung function for up to 2 hours following the Glutathion treatment. The reduction in airway function averaged some 17%. When I mentioned this to my pulmo at Tulane, he all but nixed the idea of inhaling Glutathion, saying if I wanted to take it, use it orally. So I take NAC instead, since from all I can gather, it is more readily absorbed than Glutathion through the digestive system, even though it is the precurser of Glutathion. I am curious to see what difference you see with using NAC through in nebulizer. The animal studies were pretty promising. Jerry/Mississippi/54/IPF/dx April 05 wrote: > > Bruce, > I haven't seen any published studies yet either. The Panther Trials (Prednisone, Imuran and NAC) are just getting underway and the results are a ways off yet to the best of my knowledge. > > I am immensely curious about how it will all turn out. >  > Beth > Moderator > Fibrotic NSIP 06/06 Dermatomyositis 11/08 > > > > > ________________________________ > > To: Breathe-Support > Sent: Sunday, August 23, 2009 4:19:28 PM > Subject: Re: NAC & Zyrtec > >  > To my knowledge though no trials have been completed yet and published. > Dr. Raghu may have observations from what he's seen in his portion or > discussions with colleagues. I do believe NAC helps many. But the trials > are underway. In fact these are the first trials for prednisone as well. > > > > > > > > >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com> > > >Subject: Re: vitamins and other suppliments > > >To: Breathe-Support@ yahoogroups. com > > >Date: Friday, August 21, 2009, 1:19 PM > > > > > > > > > > > >NAC did nothing for me, so I quit taking it and have several bottles > for anyone who can use them. I have had great success with Zyrtec, > which is an OTC for allergies. My theory is that it is effective in > controlling runny noses and coughing and that was my problem. After a > month, my runny nose had dried up and my coughing was down to a few > instances when I am exposed to high humidity or cold. I have been > dripless and coughless for six months. I take one a day. > > > > > > Jack > > >79/IPF - UIP/dx06/05 Maine > > > > > > > > > > > > > > > > > ____________ _________ _________ __ > > From: drisanamerry <drisanamerry@ yahoo.com> > > >To: Breathe-Support@ yahoogroups. com > > >Sent: Thursday, August 20, 2009 2:03:34 PM > > >Subject: vitamins and other suppliments > > > > > > > > >I would be interested in what other vitamins and suppliments you all > would suggest be taken. > > > > > >hugs > > > > > >merry > > > > > >I count not a day complete till needle, thread and fabric do meet. > > >2009 will be mighty fine! > > >Due to recent budget cuts and the rising cost of electricity, gas and > oil, > > >as well as current market conditions, the Light at the End of the > Tunnel has been turned off. > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 Inhaled NAC is marketed under the brand name Mucomyst. It's used with a nebulizer. We've had people on the board who have used it. Most memorably Joyce Dalton. In addition to pulmonary fibrosis, she also had bronchiectasis (an abnormal dilation of the bronchi which causes secretions to gather and pool). She used the Mucomyst, postural drainage and other things to get the mucous up and out. Just fyi NAC is also used to treat acetominophen overdose. It helps to prevent the liver damage associated with that particular OD. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 To: Breathe-Support Sent: Sunday, August 23, 2009 5:39:13 PMSubject: Re: NAC & Zyrtec From what I have gathered thus far, the animal models have shown reduction in inflamation following induced fibrosis-causing agent with inhaled NAC. And from these studies it has been assumed that human models will react similarly. Although I don't notice any appreciable difference when I don't take NAC, I feel better knowing that it isn't hurting, and most studies support using it.However, in a study of Glutathion by way of an aerosol, it was found that PFT results showed a marked reduction in lung function for up to 2 hours following the Glutathion treatment. The reduction in airway function averaged some 17%. When I mentioned this to my pulmo at Tulane, he all but nixed the idea of inhaling Glutathion, saying if I wanted to take it, use it orally. So I take NAC instead, since from all I can gather, it is more readily absorbed than Glutathion through the digestive system, even though it is the precurser of Glutathion. I am curious to see what difference you see with using NAC through in nebulizer. The animal studies were pretty promising. Jerry/Mississippi/ 54/IPF/dx April 05 wrote:>> Bruce,> I haven't seen any published studies yet either. The Panther Trials (Prednisone, Imuran and NAC) are just getting underway and the results are a ways off yet to the best of my knowledge. > > I am immensely curious about how it will all turn out. > > Beth> Moderator> Fibrotic NSIP 06/06 Dermatomyositis 11/08> > > > > ____________ _________ _________ __> From: brucemoreland <brucemoreland@ ...>> To: Breathe-Support@ yahoogroups. com> Sent: Sunday, August 23, 2009 4:19:28 PM> Subject: Re: NAC & Zyrtec> > > To my knowledge though no trials have been completed yet and published.> Dr. Raghu may have observations from what he's seen in his portion or> discussions with colleagues. I do believe NAC helps many. But the trials> are underway. In fact these are the first trials for prednisone as well.> > > >> >> > >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com>> > >Subject: Re: vitamins and other suppliments> > >To: Breathe-Support@ yahoogroups. com> > >Date: Friday, August 21, 2009, 1:19 PM> > >> > >> > >> > >NAC did nothing for me, so I quit taking it and have several bottles> for anyone who can use them. I have had great success with Zyrtec,> which is an OTC for allergies. My theory is that it is effective in> controlling runny noses and coughing and that was my problem. After a> month, my runny nose had dried up and my coughing was down to a few> instances when I am exposed to high humidity or cold. I have been> dripless and coughless for six months. I take one a day.> > >> > > Jack> > >79/IPF - UIP/dx06/05 Maine> > >> > >> > >> > >> > >> > ____________ _________ _________ __> > From: drisanamerry <drisanamerry@ yahoo.com>> > >To: Breathe-Support@ yahoogroups. com> > >Sent: Thursday, August 20, 2009 2:03:34 PM> > >Subject: vitamins and other suppliments> > >> > >> > >I would be interested in what other vitamins and suppliments you all> would suggest be taken.> > >> > >hugs> > >> > >merry> > >> > >I count not a day complete till needle, thread and fabric do meet.> > >2009 will be mighty fine!> > >Due to recent budget cuts and the rising cost of electricity, gas and> oil,> > >as well as current market conditions, the Light at the End of the> Tunnel has been turned off.> > >> > >> >> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 bruce even if the nac just relieves certain symptoms, in my opinion, it is worth it Pink Joyce R (IPF 3/06) IFA 5/09 Pennsylvania Donate Life Listed 1/09 Inactive 4/09 www.transplantfund.org--- Subject: Re: NAC & ZyrtecTo: Breathe-Support Date: Sunday, August 23, 2009, 4:19 PM To my knowledge though no trials have been completed yet and published.Dr. Raghu may have observations from what he's seen in his portion ordiscussions with colleagues. I do believe NAC helps many. But the trialsare underway. In fact these are the first trials for prednisone as well.>>> >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com>> >Subject: Re: vitamins and other suppliments> >To: Breathe-Support@ yahoogroups. com> >Date: Friday, August 21, 2009, 1:19 PM> >> >> >> >NAC did nothing for me, so I quit taking it and have several bottlesfor anyone who can use them. I have had great success with Zyrtec,which is an OTC for allergies. My theory is that it is effective incontrolling runny noses and coughing and that was my problem. After amonth, my runny nose had dried up and my coughing was down to a fewinstances when I am exposed to high humidity or cold. I have beendripless and coughless for six months. I take one a day.> >> > Jack> >79/IPF - UIP/dx06/05 Maine> >> >> >> >> >> ____________ _________ _________ __> From: drisanamerry <drisanamerry@ yahoo.com>> >To: Breathe-Support@ yahoogroups. com> >Sent: Thursday, August 20, 2009 2:03:34 PM> >Subject: vitamins and other suppliments> >> >> >I would be interested in what other vitamins and suppliments you allwould suggest be taken.> >> >hugs> >> >merry> >> >I count not a day complete till needle, thread and fabric do meet.> >2009 will be mighty fine!> >Due to recent budget cuts and the rising cost of electricity, gas andoil,> >as well as current market conditions, the Light at the End of theTunnel has been turned off.> >> >>__________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 Pink I agree, but it seems to at the very least help with mucous and may do more. Anecdotal history is sometimes more valuable than clinical trials are and if the history is people feeling it helps them then I'm all for it. Now, some do have side effects as well. I do think the clinical trials will eventually be most interesting though because up to now we have opinions and guesses on Imuran, Prednisone and NAC when it comes to IPF. To actually have some concrete data where doctors can tell patients that one in three or one in five find benefit from any of the meds will be helpful. It would be even better if the percentages were higher. We speculate about Prednisone and some will go so far as to say it never helps IPF (only IPF not the other PF's) while some will say it helps a significant percentage. Won't it be great to finally have some scientific data. Here's the problem we have with anecdotal information as opposed to clinical trials. Had I been on prednisone the past two years and still been where I am now, I can assure you that the doctors would be saying I was remaining relatively stable as a result of it and it was benefiting me because they would have no way of knowing that I would have remained relatively stable anyway. I know if I was a doctor I would feel very frustrated with nothing else to prescribe and no data on it. I would be fine on NSIP and others but I can imagine telling your patients that we don't know if prednisone helps anyone with IPF or not (beyond calming any inflammation temporarily) but we have nothing else so you decide whether to take it or not. So, you think as patients we're frustrated trying to figure it out, right now doctors have the exact same frustration. NAC falls into a huge group of drugs that we have no idea how they work or what they really might be useful for. Should everyone be taking it, not just PF'ers? Part of this is that we still know so little about our immune system. The world of rheumatology and connective tissue diseases / autoimmune diseases is terribly confusing. Even where treatments have been found, the disease is still largely not understood. I honestly believe treatments for PF will be found before the diseases are understood and their causes known. > > > > > > >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com> > > >Subject: Re: vitamins and other suppliments > > >To: Breathe-Support@ yahoogroups. com > > >Date: Friday, August 21, 2009, 1:19 PM > > > > > > > > > > > >NAC did nothing for me, so I quit taking it and have several bottles > for anyone who can use them. I have had great success with Zyrtec, > which is an OTC for allergies. My theory is that it is effective in > controlling runny noses and coughing and that was my problem. After a > month, my runny nose had dried up and my coughing was down to a few > instances when I am exposed to high humidity or cold. I have been > dripless and coughless for six months. I take one a day. > > > > > > Jack > > >79/IPF - UIP/dx06/05 Maine > > > > > > > > > > > > > > > > > ____________ _________ _________ __ > > From: drisanamerry <drisanamerry@ yahoo.com> > > >To: Breathe-Support@ yahoogroups. com > > >Sent: Thursday, August 20, 2009 2:03:34 PM > > >Subject: vitamins and other suppliments > > > > > > > > >I would be interested in what other vitamins and suppliments you all > would suggest be taken. > > > > > >hugs > > > > > >merry > > > > > >I count not a day complete till needle, thread and fabric do meet. > > >2009 will be mighty fine! > > >Due to recent budget cuts and the rising cost of electricity, gas and > oil, > > >as well as current market conditions, the Light at the End of the > Tunnel has been turned off. > > > > > > > > > > > > > > > > > > > > > > > > > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 Jerry,I don't take NAC through a nebulizer; I take in the liquid form mixed with juice. NAC has health benefits for us. Other drugs such as Prednisone suppress the immune system and NAC works to support the immune system. It also helps to produce new, healthy cells in replacement of older, unhealthy cells. It produces enzymes that protect the body from disease. Other credits include wound healing and iron absorption. Because of its immune-boosting properties, NAC is often used to protect people with AIDS from complications related to immune system deficiency. It also protects the body from the development of other illnesses, including heart disease and cancer. The development of certain eye diseases, including macular degeneration and cataracts, may be delayed by n-acetylcysteine as well. For those of you have gastrointestinal disturbances, nausea and vomiting the dosage may be too high.I don't really look for the feel-good benefits of my medication treatment for IPF. The doctors are trying to help me fight a fatal disease with what they know. Like cancer patients fighting their battle with chemotherapy drugs, I don't think I'd ask them how they feel. C_53_Familial IPF_5/09WashingtonTo: Breathe-Support Sent: Sunday, August 23, 2009 2:39:13 PMSubject: Re: NAC & Zyrtec From what I have gathered thus far, the animal models have shown reduction in inflamation following induced fibrosis-causing agent with inhaled NAC. And from these studies it has been assumed that human models will react similarly. Although I don't notice any appreciable difference when I don't take NAC, I feel better knowing that it isn't hurting, and most studies support using it. However, in a study of Glutathion by way of an aerosol, it was found that PFT results showed a marked reduction in lung function for up to 2 hours following the Glutathion treatment. The reduction in airway function averaged some 17%. When I mentioned this to my pulmo at Tulane, he all but nixed the idea of inhaling Glutathion, saying if I wanted to take it, use it orally. So I take NAC instead, since from all I can gather, it is more readily absorbed than Glutathion through the digestive system, even though it is the precurser of Glutathion. I am curious to see what difference you see with using NAC through in nebulizer. The animal studies were pretty promising. Jerry/Mississippi/ 54/IPF/dx April 05 wrote: > > Bruce, > I haven't seen any published studies yet either. The Panther Trials (Prednisone, Imuran and NAC) are just getting underway and the results are a ways off yet to the best of my knowledge. > > I am immensely curious about how it will all turn out. > > Beth > Moderator > Fibrotic NSIP 06/06 Dermatomyositis 11/08 > > > > > ____________ _________ _________ __ > From: brucemoreland <brucemoreland@ ...> > To: Breathe-Support@ yahoogroups. com > Sent: Sunday, August 23, 2009 4:19:28 PM > Subject: Re: NAC & Zyrtec > > > To my knowledge though no trials have been completed yet and published. > Dr. Raghu may have observations from what he's seen in his portion or > discussions with colleagues. I do believe NAC helps many. But the trials > are underway. In fact these are the first trials for prednisone as well. > > > > > > > > >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com> > > >Subject: Re: vitamins and other suppliments > > >To: Breathe-Support@ yahoogroups. com > > >Date: Friday, August 21, 2009, 1:19 PM > > > > > > > > > > > >NAC did nothing for me, so I quit taking it and have several bottles > for anyone who can use them. I have had great success with Zyrtec, > which is an OTC for allergies. My theory is that it is effective in > controlling runny noses and coughing and that was my problem. After a > month, my runny nose had dried up and my coughing was down to a few > instances when I am exposed to high humidity or cold. I have been > dripless and coughless for six months. I take one a day. > > > > > > Jack > > >79/IPF - UIP/dx06/05 Maine > > > > > > > > > > > > > > > > > ____________ _________ _________ __ > > From: drisanamerry <drisanamerry@ yahoo.com> > > >To: Breathe-Support@ yahoogroups. com > > >Sent: Thursday, August 20, 2009 2:03:34 PM > > >Subject: vitamins and other suppliments > > > > > > > > >I would be interested in what other vitamins and suppliments you all > would suggest be taken. > > > > > >hugs > > > > > >merry > > > > > >I count not a day complete till needle, thread and fabric do meet. > > >2009 will be mighty fine! > > >Due to recent budget cuts and the rising cost of electricity, gas and > oil, > > >as well as current market conditions, the Light at the End of the > Tunnel has been turned off. > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 Iatrogenic Bronchospasm Occurring during Clinical Trials of a New Mucolytic Agent, Acetylcysteinehttp://www.chestjournal.org/content/46/4/469.full.pdf C_53_Familial IPF_5/09WashingtonTo: Breathe-Support Sent: Sunday, August 23, 2009 1:19:28 PMSubject: Re: NAC & Zyrtec To my knowledge though no trials have been completed yet and published. Dr. Raghu may have observations from what he's seen in his portion or discussions with colleagues. I do believe NAC helps many. But the trials are underway. In fact these are the first trials for prednisone as well. > > > >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com> > >Subject: Re: vitamins and other suppliments > >To: Breathe-Support@ yahoogroups. com > >Date: Friday, August 21, 2009, 1:19 PM > > > > > > > >NAC did nothing for me, so I quit taking it and have several bottles for anyone who can use them. I have had great success with Zyrtec, which is an OTC for allergies. My theory is that it is effective in controlling runny noses and coughing and that was my problem. After a month, my runny nose had dried up and my coughing was down to a few instances when I am exposed to high humidity or cold. I have been dripless and coughless for six months. I take one a day. > > > > Jack > >79/IPF - UIP/dx06/05 Maine > > > > > > > > > > > ____________ _________ _________ __ > From: drisanamerry <drisanamerry@ yahoo.com> > >To: Breathe-Support@ yahoogroups. com > >Sent: Thursday, August 20, 2009 2:03:34 PM > >Subject: vitamins and other suppliments > > > > > >I would be interested in what other vitamins and suppliments you all would suggest be taken. > > > >hugs > > > >merry > > > >I count not a day complete till needle, thread and fabric do meet. > >2009 will be mighty fine! > >Due to recent budget cuts and the rising cost of electricity, gas and oil, > >as well as current market conditions, the Light at the End of the Tunnel has been turned off. > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 Thank you . If I ever had any doubts as to taking NAC, you have laid those doubts to rest. I know we have a lot of people on the board (in one way, too many), but I wish others with PF could gain from this kind of knowledge-sharing. I am hoping the best for you after your visit to UWMC. I could well identify with you and the side effects of prednasone at 40Mg. Down to 10 now, and I feel so much better. Jerry/Mississippi/54/IPF/dx April 05 > > > > > > > > > >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com> > > > >Subject: Re: vitamins and other suppliments > > > >To: Breathe-Support@ yahoogroups. com > > > >Date: Friday, August 21, 2009, 1:19 PM > > > > > > > > > > > > > > > >NAC did nothing for me, so I quit taking it and have several bottles > > for anyone who can use them. I have had great success with Zyrtec, > > which is an OTC for allergies. My theory is that it is effective in > > controlling runny noses and coughing and that was my problem. After a > > month, my runny nose had dried up and my coughing was down to a few > > instances when I am exposed to high humidity or cold. I have been > > dripless and coughless for six months. I take one a day. > > > > > > > > Jack > > > >79/IPF - UIP/dx06/05 Maine > > > > > > > > > > > > > > > > > > > > > > > ____________ _________ _________ __ > > > From: drisanamerry <drisanamerry@ yahoo.com> > > > >To: Breathe-Support@ yahoogroups. com > > > >Sent: Thursday, August 20, 2009 2:03:34 PM > > > >Subject: vitamins and other suppliments > > > > > > > > > > > >I would be interested in what other vitamins and suppliments you all > > would suggest be taken. > > > > > > > >hugs > > > > > > > >merry > > > > > > > >I count not a day complete till needle, thread and fabric do meet. > > > >2009 will be mighty fine! > > > >Due to recent budget cuts and the rising cost of electricity, gas and > > oil, > > > >as well as current market conditions, the Light at the End of the > > Tunnel has been turned off. > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 23, 2009 Report Share Posted August 23, 2009 Hi , I just went and muddled my way through the article in Chest Journal. From what I got, the only ones that had a problem with the NAC had asthma. Also, it said that it was administered via nebuliser. The ill effects were fixed by adding some type of bronco dialator. I wonder if it makes a difference if administered in pill form? Anyone else have any ideas on this??? Nan 49, MA List started '82 ILD '04 PF '08 Asthma '09 > > > > > > >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com> > > >Subject: Re: vitamins and other suppliments > > >To: Breathe-Support@ yahoogroups. com > > >Date: Friday, August 21, 2009, 1:19 PM > > > > > > > > > > > >NAC did nothing for me, so I quit taking it and have several bottles > for anyone who can use them. I have had great success with Zyrtec, > which is an OTC for allergies. My theory is that it is effective in > controlling runny noses and coughing and that was my problem. After a > month, my runny nose had dried up and my coughing was down to a few > instances when I am exposed to high humidity or cold. I have been > dripless and coughless for six months. I take one a day. > > > > > > Jack > > >79/IPF - UIP/dx06/05 Maine > > > > > > > > > > > > > > > > > ____________ _________ _________ __ > > From: drisanamerry <drisanamerry@ yahoo.com> > > >To: Breathe-Support@ yahoogroups. com > > >Sent: Thursday, August 20, 2009 2:03:34 PM > > >Subject: vitamins and other suppliments > > > > > > > > >I would be interested in what other vitamins and suppliments you all > would suggest be taken. > > > > > >hugs > > > > > >merry > > > > > >I count not a day complete till needle, thread and fabric do meet. > > >2009 will be mighty fine! > > >Due to recent budget cuts and the rising cost of electricity, gas and > oil, > > >as well as current market conditions, the Light at the End of the > Tunnel has been turned off. > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 24, 2009 Report Share Posted August 24, 2009 Nan, The article from Chest Journal is interesting. Personally however I'd be cautious in drawing alot of conclusions about our own treatment from it. This particular experiment was done with a very small number of asthma patients in the summer of 1962. That's 47 years ago. As I said, it's interesting but I just question it's relevence to those of us with pulmonary fibrosis. PF is not typically a disease where one produces large amounts of thick mucous. That's what Mucomyst (NAC in the nebulizer) is used for. Few, if any, of us on the board nebulize with NAC (Mucomyst) and those that do (or those members in the past who have used it) have their doctors prescribe it for a specifc reason as in the case of treating something like Bronchiectasis. The only ill effects I've ever heard anyone on the board suffering from is stomach upset. That's honestly the reason I stopped taking it. My gastroenterologist told me in no uncertain terms to stop taking it till we got my reflux under control. I stopped taking it and never started again. This can be very confusing. Most pulmonologists who know anything about ILD's usually say it might be a good idea to take NAC. We don't know if it helps but it can't really hurt. Hopefully we'll get more information and clearer answers once the Panther trials are complete. Beth Moderator Fibrotic NSIP 06/06 Dermatomyositis 11/08 To: Breathe-Support Sent: Monday, August 24, 2009 1:06:22 AMSubject: Re: NAC & Zyrtec Hi ,I just went and muddled my way through the article in Chest Journal. From what I got, the only ones that had a problem with the NAC had asthma. Also, it said that it was administered via nebuliser. The ill effects were fixed by adding some type of bronco dialator.I wonder if it makes a difference if administered in pill form?Anyone else have any ideas on this???Nan 49, MAList started '82ILD '04PF '08Asthma '09> >> >> > >From: Jack Marshall mrshlljck (AT) yahoo (DOT) com>> > >Subject: Re: vitamins and other suppliments> > >To: Breathe-Support@ yahoogroups. com> > >Date: Friday, August 21, 2009, 1:19 PM> > >> > >> > >> > >NAC did nothing for me, so I quit taking it and have several bottles> for anyone who can use them. I have had great success with Zyrtec,> which is an OTC for allergies. My theory is that it is effective in> controlling runny noses and coughing and that was my problem. After a> month, my runny nose had dried up and my coughing was down to a few> instances when I am exposed to high humidity or cold. I have been> dripless and coughless for six months. I take one a day.> > >> > > Jack> > >79/IPF - UIP/dx06/05 Maine> > >> > >> > >> > >> > >> > ____________ _________ _________ __> > From: drisanamerry <drisanamerry@ yahoo.com>> > >To: Breathe-Support@ yahoogroups. com> > >Sent: Thursday, August 20, 2009 2:03:34 PM> > >Subject: vitamins and other suppliments> > >> > >> > >I would be interested in what other vitamins and suppliments you all> would suggest be taken.> > >> > >hugs> > >> > >merry> > >> > >I count not a day complete till needle, thread and fabric do meet.> > >2009 will be mighty fine!> > >Due to recent budget cuts and the rising cost of electricity, gas and> oil,> > >as well as current market conditions, the Light at the End of the> Tunnel has been turned off.> > >> > >> >> Quote Link to comment Share on other sites More sharing options...
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