Re: Cutler Protocol Research Study

[Guest guest]

Your level of understanding of this isn't up to asking the right questions yet.

>

> I am in college and one of my assignments is to pick a project for a

> company and write a report on the main details of it. (Basically a

> glorified outline in essay form).

For what kind of class?

> I chose to do a scenario where I am a project manager for Generation

> Rescue (this is fictional) and my project is to do a study on the

> effectiveness of the Andy Cutler Chelation Protocol on children with

> autism.

>

> I was wondering if anyone would be interested in helping me with some

> details. I have chosen a 24 month time period and am still working

> on a budget.

24 months isn't long enough (because most of it would be wasted in bureaucratic

nonsense) and the budget would be millions (because most of it would be wasted

on

bureaucratic nonsense). Find out about IRB's and necessary approvals for human

subject

research and you'll see what I mean.

> Question 1: What tests would be used to measure progress, and at what

> intervals?

I would suggest behavioral tests and parent ratings using things like the ATEC

checklist,

rather than any laboratory tests. Also use the DSM-IV checklists to diagnose

them and

have the exact checklist items for each child tracked and have them re-evaluated

by new

evaluators at intervals to see which items they meet.

I would also suggest using some peer reviewed and generally accepted checklist

that is

similar in content to the non-politically-acceptable checklists used by Dan Amen

in his

books Healing ADD and Change Your Brain, Change Your Life.

> Question 2: How many participants do you feel are necessary,

Probably hundreds to be politically correct and get to an answer that is hard to

reject other

than by just saying " NO, " as all regular MD " s will anyway.

You need to reach the 95% CI on a bunch of outcomes when it is an 'either/or' or

'yes/no'

situation, and to have robust enough statitsics that one could assert that even

with some

dropouts all counted as nonresponders that it would be significant. Web tools

to do these

calculations can be found at

http://statpages.org/confint.html?

x=4.4 & N=50 & P=0.7700 & DL=0.6404 & DU=0.8694 & Z=10 & QL= & QU= & CL=95 & TU=2.5 & TL

=2.5

Let us say you have 25 kids each in the vera (treatment) and placebo arm. 5

drop out and

are lost to follow-up over the 2 year chelation time in each arm (a pretty good

retention

rate). Of the 20 remaining, 5 in the placebo arm and 15 in the treatment arm

are believed

to have improved. These results do not differ at the 95% confidence interval.

You need a

big enough trial that you do see such differences at very high statistical

confidence. And

recall, autistic children do go up and down randomly so some in the placebo arm

WILL

actually improve.

One thing you'd have to control for is institute whatever the OTHER treatments

are for

several months before beginning chelation to rate the kids and not have all the

placebo

group improve because of the nonchelation supplements.

Another thing you'd need to do is monitor very closely to ensure the parents

don't go self

activate and introduce more supplements, or do other therapies (or not count

them in the

results if they do, which many will).

> will there be specific requirements/exclusions?

There will be many, and this is where it becomes extremely difficult. One would

really

have to identify a set of subjects who could be treated EXACTLY the same way, by

rote,

rather than having individualized programs, which means some lab testing for

inclusion

and excclusion as well as doing so based on signs and symptoms.

I'd include counting rules positive children within a certain age group who had

other

specified labs being normal (CBC and thyroid being big ones) or within specified

limits.

The parents would be required to commit to not doing other biomedical or dietary

interventions, and to letting yu know what they DID do and what they fed the

kids.

You would want video diaries at specified intervals.

> Question 3: Will candida be treated in the same way for all

> participants (if need be)?

This indicates how little you really know about autism treatment and thus how

irrelevant

your paper is going to be.

It would be utterly essential that everyone did exactly the same thing other

than whether

they get true chelator (vera) or a placebo.

> Question 4: Who would participate in order for the results to be

> widely accepted? (LOL)

No. It is generally accepted as unethical to withhold an effective therapy for

research

purposes. Just because the government has created laws to protect and empower

criminals instead of to punish them doens't relieve the rest of us of reasonable

ethical

obligations to do the right thing for poor suffering children.

I don't think a reasonable parent who thoughtfully evaluates the situation

would. The

problem is 0% scientific/research related, 100% political. All the chanting

about research

is simply an attractive nuisance to keep people from doing the right thing and

putting all

their available energy into politics as single issue voters - the issue being to

eliminate all

government involvement in medicine and health care in all forms as much as is

practical.

> I would love for this to happen...like many others, so maybe after my

> assignment is done, we can talk about the real thing

Andy

[Guest guest]

Thought you might like to see my instructors comments on my paper. I

got an " A "

, What a worthy project!! The content of the study is

fascinating; I've never heard of a link between heavy metals and

autism. How exciting if the project provides hopeful results for

families impacted by autism. You did a great job on this paper. The

paper is well written and you did a good job of describing the

different components of the assignment. For example, your success

criteria are realistic and quantifiable; it will be easy to tell if

the project has achieved success. You also did a good job of

identifying your project milestones and tying the milestones to a

timeline. Nicely done!

>

> I am in college and one of my assignments is to pick a project for a

> company and write a report on the main details of it. (Basically a

> glorified outline in essay form).

>

> I chose to do a scenario where I am a project manager for Generation

> Rescue (this is fictional) and my project is to do a study on the

> effectiveness of the Andy Cutler Chelation Protocol on children with

> autism.

>

> I was wondering if anyone would be interested in helping me with

some

> details. I have chosen a 24 month time period and am still working

> on a budget.

>

> Question 1: What tests would be used to measure progress, and at

what

> intervals?

>

> Question 2: How many participants do you feel are necessary, will

> there be specific requirements/exclusions?

>

> Question 3: Will candida be treated in the same way for all

> participants (if need be)?

>

> Question 4: Who would participate in order for the results to be

> widely accepted? (LOL)

>

>

> I would love for this to happen...like many others, so maybe after

my

> assignment is done, we can talk about the real thing

>