Guest guest Posted September 14, 2008 Report Share Posted September 14, 2008 Ross, I have low ferritin and normal liver enzymes, so I'm not any help there, but I did email Andy and gave him this post number, and asked him about the PDR for DMPS and iron thing. I have no idea if he's around or how busy, but we'll see if we get an answer.--------Jackie In frequent-dose-chelation ratherto78 wrote: I am planning to start chelation with DMPS and then DMPS/ALA soon but have concerns as I have elevated iron and iron saturation levels as well as elevated AST and ALT numbers that seems to bounce around. Last few readings are: AST (0-37) 48 27 35 25 19 31 ALT (15-65) 116 77 80 90 52 83 Iron (30-170) 228 156 227 121 Iron Sat (20-50) 79 58 80 40 Ferritin (33-236) 106 160 151 I have had extensive blood work and a liver biopsy and there were no obvious finding as far as why this was occurring. My doc had suspected hemochromatosis (have a single copy of both genes but that translates to only a 3-7% chance of disease) but my ferritin numbers are low/normal and there was not a significant amount of iron in my liver tissue, although there was 'some'. Basically my docs are stumped and are taking the 'wait and see' approach. I know AI discusses unexplained elevated iron levels and liver enzymes as a symptom of Hg intoxication and I am fairly certain this is the reason for my issue. However, I have some concerns/questions: 1) I read on dmpsbackfire (not sure if this is a terribly reliable info source or not...) that DMPS is not appropriate when you have high iron: " The PDR states that Dimercaprol is...contraindicated in patients with high levels of selenium, iron, or cadmium because the resulting complexes are more toxic than the metal itself, especially to the kidneys. " Anyone (Andy) have opinions on this? 2) Does anyone here have first hand experience with these issues that were solved by DMSA/DMPS/ALA frequent dose chelation? 3) My doc is telling me to limit my vitamin C intake because it can cause increased iron absorption in the intestines. This is a problem as far as chelation and cutler protocol supplementation. I am trying to figure out if it is better to limit C or just take the cutler protocol doses and disregard the doc. I am curious if anyone has any data that would support or negate this theory of absorption. I have found conflicting data and don't know what to make of it. I realize this is a lengthy and specific request so whatever anyone can add is greatly appreciated. Thanks, Ross Quote Link to comment Share on other sites More sharing options...
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