Guest guest Posted April 18, 2008 Report Share Posted April 18, 2008 Comments: Hydrocortisone is powerful stuff! Wow. People here and at other forums talk all the time about their 20mg doses like it was routine. I tell you what, 5mg hit me like a ton of bricks. Doc just prescribed HC for hypoadrenalism. Very low cortisol by day, with elevated cortisol beginning about 2am and crashing by 9am. Anyway, much more depressed. I mean, really, wicked depression. Like 5mg all at once or 2.5mg spread out just totally shut down the works. So now I am taking 1.25mg at 9am and 1.25mg at noon with tolerable results thus far. A noticable boost of energy and concentration, nothing miraculous though, but certainly a welcome hint of change, and some aggravation/irritation in early evening. My psychiatric state doesn't seem to like HC much, but my body does. I noticed right away some creases and wrinkles in the skin were less noticable. HC = good skin? Appetite seems better. Stools are much better. I won't get into details, just to say they seem healthy and normal instead of erratic. Anyway, I just wanted to comment on how powerful tiny amounts of HC are to me, when other people handle much larger doses like it is nothing. Question: Common sense says take HC when the daily rythym is low, which for most of us is in the day. But for those of us with nightime excessive peaks, I wonder, has anyone tried taking HC at that time to force bodily production of cortisol to stop? I am thinking maybe the feedback loops would sense the HC and stop any further production of cortisol and thus prevent the wrong peaks. Maybe in time that could retrain things? Purely a hypothetical question. Just wondering. Sometimes what appears illogical is actually perfectly logical? I have my doubts though, because if the feedback loops are to kick in and shut things down, well, then why do they allow extreme excess cortisol production at night? Don't they know things are too extreme already? Anyway, just wondering if anyone had any thoughts of taking HC at times of inappropriate excess cortisol production in order to force production down. Comments welcome. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 19, 2008 Report Share Posted April 19, 2008 If your cortisol is elevated in the evening, when it should be going down, you may be having trouble with blood sugar levels. It's really important to maintain your blood sugar by eating frequently, and with enough protein/fewer high glycemic carbs. This can be particularly difficult if you only eat when you feel hungry. You may not be eating often enough. Try snacking more frequently throughout the day/evening, with adequate protein. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 19, 2008 Report Share Posted April 19, 2008 Thanks for posting this. I had a very similar experience this week. I couldn't figure out what was going on until yesterday when I realized it must be the HC. I've taken this much before (5 mg in AM 2.5 mg mid-day), but only for " stress dosing. " Taking it for several days in a row made me the most depressed I've been, well, maybe ever, and it also increased my level of fatigue. I'll try the 1.25 mg dose and see if that works better. Dana _____ From: frequent-dose-chelation [mailto:frequent-dose-chelation ] On Behalf Of stringworship Hydrocortisone is powerful stuff! Wow. People here and at other forums talk all the time about their 20mg doses like it was routine. I tell you what, 5mg hit me like a ton of bricks. Doc just prescribed HC for hypoadrenalism. Very low cortisol by day, with elevated cortisol beginning about 2am and crashing by 9am. Anyway, much more depressed. I mean, really, wicked depression. Like 5mg all at once or 2.5mg spread out just totally shut down the works. So now I am taking 1.25mg at 9am and 1.25mg at noon with tolerable results thus far. A noticable boost of energy and concentration, nothing miraculous though, but certainly a welcome hint of change, and some aggravation/irritation in early evening. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 19, 2008 Report Share Posted April 19, 2008 ----I would highly recommend looking into this group: http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/? yguid=214911544 and this one as well: http://health.groups.yahoo.com/group/NaturalThyroidHormones/? yguid=214911544 These folks really know their stuff when it comes to thyriod/adrenals. I have gleaned a lot of knowledge from them. Summer > Hydrocortisone is powerful stuff! Wow. People here and at other > forums talk all the time about their 20mg doses like it was routine. > I tell you what, 5mg hit me like a ton of bricks. Doc just > prescribed HC for hypoadrenalism. Very low cortisol by day, with > elevated cortisol beginning about 2am and crashing by 9am. Anyway, > much more depressed. I mean, really, wicked depression. Like 5mg all > at once or 2.5mg spread out just totally shut down the works. > > So now I am taking 1.25mg at 9am and 1.25mg at noon with tolerable > results thus far. A noticable boost of energy and concentration, > nothing miraculous though, but certainly a welcome hint of change, > and some aggravation/irritation in early evening. > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 19, 2008 Report Share Posted April 19, 2008 > > Comments: > Hydrocortisone is powerful stuff! Wow. People here and at other > forums talk all the time about their 20mg doses like it was routine. Yeah, I've always been a little nervous about this. Whenever I've been given cortizone it's made me severely nauseous for 2 days afterwards, even when being used topically in physical therapy. And yet I'm low cortisol, so you'd think it'd give me a boost. Since I haven't found a doctor who'll prescribe HC, it's kind of moot, but I feel better knowing there are others who need it in small doses. <snip> > > Question: Common sense says take HC when the daily rythym is low, > which for most of us is in the day. But for those of us with > nightime excessive peaks, I wonder, has anyone tried taking HC at > that time to force bodily production of cortisol to stop? I am > thinking maybe the feedback loops would sense the HC and stop any > further production of cortisol and thus prevent the wrong peaks. > Maybe in time that could retrain things? Purely a hypothetical > question. Just wondering. Sometimes what appears illogical is > actually perfectly logical? I have my doubts though, because if the > feedback loops are to kick in and shut things down, well, then why > do they allow extreme excess cortisol production at night? Don't > they know things are too extreme already? Anyway, just wondering if > anyone had any thoughts of taking HC at times of inappropriate > excess cortisol production in order to force production down. > > Comments welcome. > Wasn't there something in AI about high cortisol at night? Maybe phosphadlycholine (sp?) But I think your doubts are sound... if the feedback loops were working so that they'd stop production if you gave HC, then they should be working to prevent the excess production in the first place. Interesting idea anyway. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 19, 2008 Report Share Posted April 19, 2008 > > Comments: > Hydrocortisone is powerful stuff! Wow. People here and at other > forums talk all the time about their 20mg doses like it was routine. 20 mg (or more) is now routine for me. When I started with a dose of 1.25 mg it felt like *way too much*. I backed off to .625 mg for a bit before trying 1.25 mg again and then gradually worked up over a period of months. > I tell you what, 5mg hit me like a ton of bricks. Doc just > prescribed HC for hypoadrenalism. Very low cortisol by day, with > elevated cortisol beginning about 2am and crashing by 9am. Anyway, > much more depressed. I mean, really, wicked depression. Like 5mg all > at once or 2.5mg spread out just totally shut down the works. My initial symptoms were not the same as yours, but I did develop some fatigue/depression as my dose got higher, maybe within a month or so. > So now I am taking 1.25mg at 9am and 1.25mg at noon with tolerable > results thus far. A noticable boost of energy and concentration, > nothing miraculous though, but certainly a welcome hint of change, > and some aggravation/irritation in early evening. > > My psychiatric state doesn't seem to like HC much, but my body does. > I noticed right away some creases and wrinkles in the skin were less > noticable. HC = good skin? Appetite seems better. Stools are much > better. I won't get into details, just to say they seem healthy and > normal instead of erratic. > > Anyway, I just wanted to comment on how powerful tiny amounts of HC > are to me, when other people handle much larger doses like it is > nothing. As described above, it was quite powerful for me, too. I think it was because I needed it. I gradually tolerated more. > Question: Common sense says take HC when the daily rythym is low, > which for most of us is in the day. But for those of us with > nightime excessive peaks, I wonder, has anyone tried taking HC at > that time to force bodily production of cortisol to stop? I am > thinking maybe the feedback loops would sense the HC and stop any > further production of cortisol and thus prevent the wrong peaks. > Maybe in time that could retrain things? Purely a hypothetical > question. Just wondering. Sometimes what appears illogical is > actually perfectly logical? I have my doubts though, because if the > feedback loops are to kick in and shut things down, well, then why > do they allow extreme excess cortisol production at night? Don't > they know things are too extreme already? Anyway, just wondering if > anyone had any thoughts of taking HC at times of inappropriate > excess cortisol production in order to force production down. I have heard some people report that taking a small dose of cortisol before bed seems to help them sleep. For me, taking a lot in the morning seemed to help me sleep at night (I was desperate for sleep at the time, getting very little). When my morning dose got up to about 10 mg, that's when I started noticing improved sleep at night. It got better with higher doses. I still have some trouble waking too early, so sometimes I take HC early (such as 5 am) and it helps me go back to sleep. I have never tested my cortisol level at that hour, but I think it may vary, sometimes relatively high and sometimes low. I think the HC helps more when it is low, but that is somewhat a guess. -- > Comments welcome. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 19, 2008 Report Share Posted April 19, 2008 It's interesting that you had this reaction to the HC. Are you using Cortef or some other form? I have heard some people started with very low doses and worked up. I have heard of others who started with high doses and then gradually worked down to maintenance dose. For me, it was totally opposite. I started right away at 20 mg per dose, and I started sleeping 18 h per day. My doc had to finally increased the dose to cut my fatigue. J > > Comments: > Hydrocortisone is powerful stuff! Wow. People here and at other > forums talk all the time about their 20mg doses like it was routine. > I tell you what, 5mg hit me like a ton of bricks. Doc just > prescribed HC for hypoadrenalism. Very low cortisol by day, with > elevated cortisol beginning about 2am and crashing by 9am. Anyway, > much more depressed. I mean, really, wicked depression. Like 5mg all > at once or 2.5mg spread out just totally shut down the works. > > So now I am taking 1.25mg at 9am and 1.25mg at noon with tolerable > results thus far. A noticable boost of energy and concentration, > nothing miraculous though, but certainly a welcome hint of change, > and some aggravation/irritation in early evening. > > My psychiatric state doesn't seem to like HC much, but my body does. > I noticed right away some creases and wrinkles in the skin were less > noticable. HC = good skin? Appetite seems better. Stools are much > better. I won't get into details, just to say they seem healthy and > normal instead of erratic. > > Anyway, I just wanted to comment on how powerful tiny amounts of HC > are to me, when other people handle much larger doses like it is > nothing. > > Question: Common sense says take HC when the daily rythym is low, > which for most of us is in the day. But for those of us with > nightime excessive peaks, I wonder, has anyone tried taking HC at > that time to force bodily production of cortisol to stop? I am > thinking maybe the feedback loops would sense the HC and stop any > further production of cortisol and thus prevent the wrong peaks. > Maybe in time that could retrain things? Purely a hypothetical > question. Just wondering. Sometimes what appears illogical is > actually perfectly logical? I have my doubts though, because if the > feedback loops are to kick in and shut things down, well, then why > do they allow extreme excess cortisol production at night? Don't > they know things are too extreme already? Anyway, just wondering if > anyone had any thoughts of taking HC at times of inappropriate > excess cortisol production in order to force production down. > > Comments welcome. > Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.