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Hydrocortisone is powerful stuff! Wow. People here and at other

forums talk all the time about their 20mg doses like it was routine.

I tell you what, 5mg hit me like a ton of bricks. Doc just

prescribed HC for hypoadrenalism. Very low cortisol by day, with

elevated cortisol beginning about 2am and crashing by 9am. Anyway,

much more depressed. I mean, really, wicked depression. Like 5mg all

at once or 2.5mg spread out just totally shut down the works.

So now I am taking 1.25mg at 9am and 1.25mg at noon with tolerable

results thus far. A noticable boost of energy and concentration,

nothing miraculous though, but certainly a welcome hint of change,

and some aggravation/irritation in early evening.

My psychiatric state doesn't seem to like HC much, but my body does.

I noticed right away some creases and wrinkles in the skin were less

noticable. HC = good skin? Appetite seems better. Stools are much

better. I won't get into details, just to say they seem healthy and

normal instead of erratic.

Anyway, I just wanted to comment on how powerful tiny amounts of HC

are to me, when other people handle much larger doses like it is

nothing.

Question: Common sense says take HC when the daily rythym is low,

which for most of us is in the day. But for those of us with

nightime excessive peaks, I wonder, has anyone tried taking HC at

that time to force bodily production of cortisol to stop? I am

thinking maybe the feedback loops would sense the HC and stop any

further production of cortisol and thus prevent the wrong peaks.

Maybe in time that could retrain things? Purely a hypothetical

question. Just wondering. Sometimes what appears illogical is

actually perfectly logical? I have my doubts though, because if the

feedback loops are to kick in and shut things down, well, then why

do they allow extreme excess cortisol production at night? Don't

they know things are too extreme already? Anyway, just wondering if

anyone had any thoughts of taking HC at times of inappropriate

excess cortisol production in order to force production down.

Comments welcome.

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If your cortisol is elevated in the evening, when it should be going down, you

may be having

trouble with blood sugar levels.

It's really important to maintain your blood sugar by eating frequently, and

with enough

protein/fewer high glycemic carbs.

This can be particularly difficult if you only eat when you feel hungry. You

may not be eating

often enough.

Try snacking more frequently throughout the day/evening, with adequate protein.

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Thanks for posting this. I had a very similar experience this week. I

couldn't figure out what was going on until yesterday when I realized it

must be the HC. I've taken this much before (5 mg in AM 2.5 mg mid-day), but

only for " stress dosing. " Taking it for several days in a row made me the

most depressed I've been, well, maybe ever, and it also increased my level

of fatigue. I'll try the 1.25 mg dose and see if that works better.

Dana

_____

From: frequent-dose-chelation

[mailto:frequent-dose-chelation ] On Behalf Of stringworship

Hydrocortisone is powerful stuff! Wow. People here and at other

forums talk all the time about their 20mg doses like it was routine.

I tell you what, 5mg hit me like a ton of bricks. Doc just

prescribed HC for hypoadrenalism. Very low cortisol by day, with

elevated cortisol beginning about 2am and crashing by 9am. Anyway,

much more depressed. I mean, really, wicked depression. Like 5mg all

at once or 2.5mg spread out just totally shut down the works.

So now I am taking 1.25mg at 9am and 1.25mg at noon with tolerable

results thus far. A noticable boost of energy and concentration,

nothing miraculous though, but certainly a welcome hint of change,

and some aggravation/irritation in early evening.

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----I would highly recommend looking into this group:

http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/?

yguid=214911544

and this one as well:

http://health.groups.yahoo.com/group/NaturalThyroidHormones/?

yguid=214911544

These folks really know their stuff when it comes to

thyriod/adrenals. I have gleaned a lot of knowledge from them.

Summer

> Hydrocortisone is powerful stuff! Wow. People here and at other

> forums talk all the time about their 20mg doses like it was

routine.

> I tell you what, 5mg hit me like a ton of bricks. Doc just

> prescribed HC for hypoadrenalism. Very low cortisol by day, with

> elevated cortisol beginning about 2am and crashing by 9am. Anyway,

> much more depressed. I mean, really, wicked depression. Like 5mg

all

> at once or 2.5mg spread out just totally shut down the works.

>

> So now I am taking 1.25mg at 9am and 1.25mg at noon with tolerable

> results thus far. A noticable boost of energy and concentration,

> nothing miraculous though, but certainly a welcome hint of change,

> and some aggravation/irritation in early evening.

>

>

>

>

>

>

>

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>

> Comments:

> Hydrocortisone is powerful stuff! Wow. People here and at other

> forums talk all the time about their 20mg doses like it was routine.

Yeah, I've always been a little nervous about this. Whenever I've

been given cortizone it's made me severely nauseous for 2 days

afterwards, even when being used topically in physical therapy. And

yet I'm low cortisol, so you'd think it'd give me a boost. Since I

haven't found a doctor who'll prescribe HC, it's kind of moot, but I

feel better knowing there are others who need it in small doses.

<snip>

>

> Question: Common sense says take HC when the daily rythym is low,

> which for most of us is in the day. But for those of us with

> nightime excessive peaks, I wonder, has anyone tried taking HC at

> that time to force bodily production of cortisol to stop? I am

> thinking maybe the feedback loops would sense the HC and stop any

> further production of cortisol and thus prevent the wrong peaks.

> Maybe in time that could retrain things? Purely a hypothetical

> question. Just wondering. Sometimes what appears illogical is

> actually perfectly logical? I have my doubts though, because if the

> feedback loops are to kick in and shut things down, well, then why

> do they allow extreme excess cortisol production at night? Don't

> they know things are too extreme already? Anyway, just wondering if

> anyone had any thoughts of taking HC at times of inappropriate

> excess cortisol production in order to force production down.

>

> Comments welcome.

>

Wasn't there something in AI about high cortisol at night? Maybe

phosphadlycholine (sp?)

But I think your doubts are sound... if the feedback loops were

working so that they'd stop production if you gave HC, then they

should be working to prevent the excess production in the first place.

Interesting idea anyway.

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>

> Comments:

> Hydrocortisone is powerful stuff! Wow. People here and at other

> forums talk all the time about their 20mg doses like it was routine.

20 mg (or more) is now routine for me. When I started with a dose

of 1.25 mg it felt like *way too much*. I backed off to .625 mg for

a bit before trying 1.25 mg again and then gradually worked up over

a period of months.

> I tell you what, 5mg hit me like a ton of bricks. Doc just

> prescribed HC for hypoadrenalism. Very low cortisol by day, with

> elevated cortisol beginning about 2am and crashing by 9am. Anyway,

> much more depressed. I mean, really, wicked depression. Like 5mg all

> at once or 2.5mg spread out just totally shut down the works.

My initial symptoms were not the same as yours, but I did develop

some fatigue/depression as my dose got higher, maybe within a month

or so.

> So now I am taking 1.25mg at 9am and 1.25mg at noon with tolerable

> results thus far. A noticable boost of energy and concentration,

> nothing miraculous though, but certainly a welcome hint of change,

> and some aggravation/irritation in early evening.

>

> My psychiatric state doesn't seem to like HC much, but my body does.

> I noticed right away some creases and wrinkles in the skin were less

> noticable. HC = good skin? Appetite seems better. Stools are much

> better. I won't get into details, just to say they seem healthy and

> normal instead of erratic.

>

> Anyway, I just wanted to comment on how powerful tiny amounts of HC

> are to me, when other people handle much larger doses like it is

> nothing.

As described above, it was quite powerful for me, too. I think it

was because I needed it. I gradually tolerated more.

> Question: Common sense says take HC when the daily rythym is low,

> which for most of us is in the day. But for those of us with

> nightime excessive peaks, I wonder, has anyone tried taking HC at

> that time to force bodily production of cortisol to stop? I am

> thinking maybe the feedback loops would sense the HC and stop any

> further production of cortisol and thus prevent the wrong peaks.

> Maybe in time that could retrain things? Purely a hypothetical

> question. Just wondering. Sometimes what appears illogical is

> actually perfectly logical? I have my doubts though, because if the

> feedback loops are to kick in and shut things down, well, then why

> do they allow extreme excess cortisol production at night? Don't

> they know things are too extreme already? Anyway, just wondering if

> anyone had any thoughts of taking HC at times of inappropriate

> excess cortisol production in order to force production down.

I have heard some people report that taking a small dose of cortisol

before bed seems to help them sleep.

For me, taking a lot in the morning seemed to help me sleep at night

(I was desperate for sleep at the time, getting very little). When

my morning dose got up to about 10 mg, that's when I started noticing

improved sleep at night. It got better with higher doses. I still

have some trouble waking too early, so sometimes I take HC early

(such as 5 am) and it helps me go back to sleep. I have never tested

my cortisol level at that hour, but I think it may vary, sometimes

relatively high and sometimes low. I think the HC helps more when it

is low, but that is somewhat a guess.

--

> Comments welcome.

>

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It's interesting that you had this reaction to the HC. Are you using

Cortef or some other form? I have heard some people started with very

low doses and worked up. I have heard of others who started with high

doses and then gradually worked down to maintenance dose.

For me, it was totally opposite. I started right away at 20 mg per

dose, and I started sleeping 18 h per day. My doc had to finally

increased the dose to cut my fatigue.

J

>

> Comments:

> Hydrocortisone is powerful stuff! Wow. People here and at other

> forums talk all the time about their 20mg doses like it was routine.

> I tell you what, 5mg hit me like a ton of bricks. Doc just

> prescribed HC for hypoadrenalism. Very low cortisol by day, with

> elevated cortisol beginning about 2am and crashing by 9am. Anyway,

> much more depressed. I mean, really, wicked depression. Like 5mg all

> at once or 2.5mg spread out just totally shut down the works.

>

> So now I am taking 1.25mg at 9am and 1.25mg at noon with tolerable

> results thus far. A noticable boost of energy and concentration,

> nothing miraculous though, but certainly a welcome hint of change,

> and some aggravation/irritation in early evening.

>

> My psychiatric state doesn't seem to like HC much, but my body does.

> I noticed right away some creases and wrinkles in the skin were less

> noticable. HC = good skin? Appetite seems better. Stools are much

> better. I won't get into details, just to say they seem healthy and

> normal instead of erratic.

>

> Anyway, I just wanted to comment on how powerful tiny amounts of HC

> are to me, when other people handle much larger doses like it is

> nothing.

>

> Question: Common sense says take HC when the daily rythym is low,

> which for most of us is in the day. But for those of us with

> nightime excessive peaks, I wonder, has anyone tried taking HC at

> that time to force bodily production of cortisol to stop? I am

> thinking maybe the feedback loops would sense the HC and stop any

> further production of cortisol and thus prevent the wrong peaks.

> Maybe in time that could retrain things? Purely a hypothetical

> question. Just wondering. Sometimes what appears illogical is

> actually perfectly logical? I have my doubts though, because if the

> feedback loops are to kick in and shut things down, well, then why

> do they allow extreme excess cortisol production at night? Don't

> they know things are too extreme already? Anyway, just wondering if

> anyone had any thoughts of taking HC at times of inappropriate

> excess cortisol production in order to force production down.

>

> Comments welcome.

>

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