cold and Oxaliplatin

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Oxaliplatin may cause nerve damage such as: becoming very sensitive to cold

temperatures and cold objects, trouble breathing, swallowing or saying words,

jaw tightness, odd feelings in your tongue, a " pins and needles " feeling or

a numbing of your hands, feet or around your mouth or throat.

Avoid cold temperatures and cold objects. Cover your skin if you must go

outside in cold temperatures. The following is a list of ways you can reduce

the

side effect caused by cold temperatures:

·do not breathe deeply when exposed to cold air;

·don't take things from the refrigerator or freezer without wearing gloves;

·do not run the air conditioner at high levels in the house or in the car in

hot weather;

·do not drink cold drinks or use ice cubes in drinks;

·do not put ice packs on your body;

·Do Not use ice chips if you have nausea or mouth sores. Ask your nurse

about what you can use.

• You need to discuss your level of activity during treatment with your

doctor and your nurse. You should follow their advice.

• Oxaliplatin can lower the activity of your immune system making you

susceptible to infections. Avoid contact with people who have colds, the flu,

or

other contagious illnesses and do not receive vaccines that contain live

strains of a virus (e.g., live oral polio vaccine) during treatment with

oxaliplatin. In addition, avoid contact with individuals who have recently been

vaccinated with a live vaccine. There is a chance that the virus can be passed

on to

you.