Guest guest Posted April 22, 2008 Report Share Posted April 22, 2008 > > > > > > Yeah, I've always been a little nervous about this. Whenever I've > > been given cortizone it's made me severely nauseous for 2 days > > afterwards, even when being used topically in physical therapy. > > The nausea comes from the brain sending out ACTH. The adrenals are > waiting for the cortisol to be supplied orally or topically are are > being lazy, so don't immediately respond and ACTH keeps coming. It > is the buildup of ACTH that leads to nausea. This has happened to > me lots when I miss a dose or when I'm changing the dose schedule. > > J > , thanks so much for explaining this! It really makes sense, especially since I also got really nauseous when they did the cortisol stimulation test, which is injections of ACTH. I hadn't been able to figure that one out. Quote Link to comment Share on other sites More sharing options...
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