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Merf

Congratulations and good luck.

For those not aware this is a Phase II study. This drug is also being

studied for cancer tumors.

For this study one must have FVC over 50%. It is starting with a small

group and if there are no serious adverse issues, more persons will be

added. One may get either the placebo or one of three different dosages.

The drug will only be given for 48 weeks. However, the patients will be

followed and tracked for 74 weeks to evaluate what happens when taken

off the drug.

Most of the studies we've seen here and talked about such as

Pirfenidone, Revatio, and Tracleer have been phase III studies so Merf

truly is getting in on a very early and new study.

>

> Hi Gang. I know I haven't been in the group very long but just wanted

to let you know I have been accepted in a clinical trial. It is a phase

2 multinational doubleblind etc. etc,etc, of drug called CNTO888

administered intravenously to patients with IPF. It is sponsored by

Centocor, which is & . The last screening process took

7hrs in hospital. 2 Psyc. evaualtions plus all the other tests we all

take. Hate the PFT. Would like to stomp the h... out of that little

laptop. Start next wed july 28. The length of the test is 72 weeks.

First visit is about 6hrs. My wife is allowed to accompany me for most

of what is going on. Glad she is there as I am sort of

apprehensive,nervous,curious and she keeps reassuring me. Question they

kept throwing at me was did I expect this to help me now. Told them I

knew if they found something good it is probably too late for me but it

can help others coming up behind me. Sorry for rambling guys but a lot

going through my mind now. If you want will keep you updated with posts.

Could almost make it like a journal. O YES WANT A BUNCH OF THOSE

T-SHIRTS WHEN READY.

> Merf 61 IPF 05

>

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Merf,

This is pretty exciting. I'm sure you must be a bit anxious but you are doing this with such a great mindset and a real generous spirit. Thank you from all of us!

Please stick close and keep us posted as to how you are doing!!

Beth

Moderator

Fibrotic NSIP 06/06 Dermatomyositis 11/08

To: Breathe-Support Sent: Friday, July 24, 2009 8:06:20 PMSubject: Clinical Trials

Hi Gang. I know I haven't been in the group very long but just wanted to let you know I have been accepted in a clinical trial. It is a phase 2 multinational doubleblind etc. etc,etc, of drug called CNTO888 administered intravenously to patients with IPF. It is sponsored by Centocor, which is & . The last screening process took 7hrs in hospital. 2 Psyc. evaualtions plus all the other tests we all take. Hate the PFT. Would like to stomp the h... out of that little laptop. Start next wed july 28. The length of the test is 72 weeks. First visit is about 6hrs. My wife is allowed to accompany me for most of what is going on. Glad she is there as I am sort of apprehensive, nervous,curious and she keeps reassuring me. Question they kept throwing at me was did I expect this to help me now. Told them I knew if they found something good it is probably too late for me but it can help others coming up behind me. Sorry for rambling guys but a

lot going through my mind now. If you want will keep you updated with posts. Could almost make it like a journal. O YES WANT A BUNCH OF THOSE T-SHIRTS WHEN READY.Merf 61 IPF 05

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Merf,

You are that speciall soldier on the front line who makes things better for us waiting behind. Which center are you going to? Who knows, hang in there and you may be luckier than you know. I can't wait to hear how things go for you.

Jerry/Mississippi/54/IPF/dx April 05Who believes that hard times help us appreciate the good times even more.

Subject: Clinical TrialsTo: Breathe-Support Date: Saturday, July 25, 2009, 12:06 AM

Hi Gang. I know I haven't been in the group very long but just wanted to let you know I have been accepted in a clinical trial. It is a phase 2 multinational doubleblind etc. etc,etc, of drug called CNTO888 administered intravenously to patients with IPF. It is sponsored by Centocor, which is & . The last screening process took 7hrs in hospital. 2 Psyc. evaualtions plus all the other tests we all take. Hate the PFT. Would like to stomp the h... out of that little laptop. Start next wed july 28. The length of the test is 72 weeks. First visit is about 6hrs. My wife is allowed to accompany me for most of what is going on. Glad she is there as I am sort of apprehensive, nervous,curious and she keeps reassuring me. Question they kept throwing at me was did I expect this to help me now. Told them I knew if they found something good it is probably too late for me but it can help others coming up behind me. Sorry for rambling guys but a

lot going through my mind now. If you want will keep you updated with posts. Could almost make it like a journal. O YES WANT A BUNCH OF THOSE T-SHIRTS WHEN READY.Merf 61 IPF 05

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Merf. I do wish you all the best. We will all be watching the results.. We do appreciate you. Love and Prayers, Peggy IPF 2004, FloridaWorry looks around, Sorry looks back, Faith looks up. Hi Gang. I know I haven't been in the group very long but just wanted to let you know I have been accepted in a clinical trial. It is a phase 2 multinational doubleblind etc. etc,etc, of drug called CNTO888 administered intravenously to patients with IPF. It is sponsored by Centocor, which is & . The last screening process took 7hrs in hospital. 2 Psyc. evaualtions plus all the other tests we all take. Hate the PFT. Would like to stomp the h... out of that little laptop. Start next wed july 28. The length of the test is 72 weeks. First visit is about 6hrs. My wife is allowed to accompany me for most of what is going on. Glad she is there as I am sort of apprehensive,nervous,curious and she keeps reassuring me. Question they kept throwing at me was did I expect this to help me now. Told them I knew if they found something good it is probably too late for me but it can help others coming up behind me. Sorry for rambling guys but a lot going through my mind now. If you want will keep you updated with posts. Could almost make it like a journal. O YES WANT A BUNCH OF THOSE T-SHIRTS WHEN READY. Merf 61 IPF 05

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