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Re: Hg and elevated iron levels/liver enzymes

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I should have been more specific in some of my questions...

1) This was a dumb question as I need to get the iron down regardless

of if I chelate or not, disregard.

2) Same - Does anyone here have first hand experience with these

issues that were solved by DMSA/DMPS/ALA frequent dose chelation?

3) A better version of this question would have been 'does anyone know

of ways to reduce iron absorption?' I have read that black tea and

some herbal teas do this. Also that taking Ca with meals can help

block absorbtion.

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>> I have had extensive blood work and a liver biopsy and there were no

>> obvious finding as far as why this was occurring. My doc had

>> suspected hemochromatosis (have a single copy of both genes but that

>> translates to only a 3-7% chance of disease) but my ferritin numbers

>> are low/normal and there was not a significant amount of iron in my

>> liver tissue, although there was 'some'. Basically my docs are

>> stumped and are taking the 'wait and see' approach.

>>

>> I know AI discusses unexplained elevated iron levels and liver

> enzymes

>> as a symptom of Hg intoxication and I am fairly certain this is the

>> reason for my issue. However, I have some concerns/questions:

Hi Ros,

Your Ferritin is quite normal.

I was under the impression that this is the most important indicator of

hemochromatosis?

I know of someone that got it down from 800 to 150 over 4 months doing some

blood letting once a month.

Andy likes ferritin between 30-90 if I'm not mistaken, as it has a highly

oxidizing effect in combination of mercury.

Thanks,

DeanSA

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>I did email Andy and gave him this post number, and asked him about

>the PDR for DMPS and iron thing. I have no idea if he's around or

how >busy, but we'll see if we get an answer.--------Jackie

Thank you for doing that Jackie, and for all the responses. It looks

like I am doing a lot of things that are good for blocking absorption

already, and plan to add some more like more taurine, IP6, and Ca with

meals.

Per your comment Dean, you are correct that Ferritin is the main

indicator for hemochromatosis as far as I am aware. My current docs

are pretty poor and they were grasping at that diagnosis because

everything else seemed to fit (symptoms, other aspects of bloodwork).

Basically they had no idea and just biopsied me and then still had no

idea...seems to be par for the course with my medical adventures!

Thanks again all,

Ross

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My husband was diagnosed with hemochromatosis several years ago. The

only way to control it is by blood letting. He does that once a month

and he's good.

We follow the other precautions but nothing has seemed to matter but

the blood letting. Iron rich blood is fine for donations - when he was

first diagnosed, the Red Cross wouldn't take it. Now they will.

We are looking forward to the chelation, see how that goes for him.

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>

> I am planning to start chelation with DMPS and then DMPS/ALA soon but

> have concerns as I have elevated iron and iron saturation levels as

> well as elevated AST and ALT numbers that seems to bounce around.

> Last few readings are:

>

> AST (0-37) 48 27 35 25 19 31

> ALT (15-65) 116 77 80 90 52 83

> Iron (30-170) 228 156 227 121

> Iron Sat (20-50) 79 58 80 40

> Ferritin (33-236) 106 160 151

>

> I have had extensive blood work and a liver biopsy and there were no

> obvious finding as far as why this was occurring. My doc had

> suspected hemochromatosis (have a single copy of both genes but that

> translates to only a 3-7% chance of disease) but my ferritin numbers

> are low/normal and there was not a significant amount of iron in my

> liver tissue, although there was 'some'. Basically my docs are

> stumped and are taking the 'wait and see' approach.

I can't imagine how those tests translate into a liver biopsy being ethical to

perform on

you. You must have had something else going on clinically.

The numbers are fine. Generally MD's blow off ALT and AST under 100 anyway.

I've never heard of any contraindication for DMPS with high iron, and I've had

people with

ferritins around 8-900 chelate just fine.

> I know AI discusses unexplained elevated iron levels and liver enzymes

> as a symptom of Hg intoxication and I am fairly certain this is the

> reason for my issue. However, I have some concerns/questions:

>

> 1) I read on dmpsbackfire (not sure if this is a terribly reliable

> info source or not...) that DMPS is not appropriate when you have high

> iron:

It reliably reports the results that can be expected from letting a doctor

irresponsibly inject

you with DMPS. Other details may not be fully accurate - the people writing it

do have a

bad attitude about DMPS so they may exaggerate the dangers of it when used

properly.

> " The PDR states that Dimercaprol is

Dimercaprol is not DMPS. It is BAL. A very different compound.

>...contraindicated in patients with

> high levels of selenium, iron, or cadmium because the resulting

> complexes are more toxic than the metal itself, especially to the

> kidneys. "

>

> Anyone (Andy) have opinions on this?

>

> 2) Does anyone here have first hand experience with these issues that

> were solved by DMSA/DMPS/ALA frequent dose chelation?

>

> 3) My doc is telling me to limit my vitamin C intake because it can

> cause increased iron absorption in the intestines.

Your ferritin is perfectly reasonable, that is the best measure of body stores.

The periodic high irons actually are more consistent with hemolytic events

(destruction of

a lot of blood cells) than with iron overload. E. g. due to getting bruised a

lot, or to certain

medical conditions.

I wouldn't suggest you limit it, you might limit dietary iron instead.

> This is a problem

> as far as chelation and cutler protocol supplementation. I am trying

> to figure out if it is better to limit C or just take the cutler

> protocol doses and disregard the doc. I am curious if anyone has any

> data that would support or negate this theory of absorption. I have

> found conflicting data and don't know what to make of it.

Vitamin C does increase iron absorption.

It is not at all clear if you have too much iron.

I'd love to know why they did the liver biopsy, that might be relevant.

>

> I realize this is a lengthy and specific request so whatever anyone

> can add is greatly appreciated.

>

> Thanks,

>

> Ross

>

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