Re: Re: Andy - modified dosing schedule okay?

[Guest guest]

In frequent-dose-chelation Dean wrote:

" You should not go longer than 3hr for the night

doses if you extend the lenght between doses. If you go longer than

1 hr from the last dose you are supposed to stop the round. "

TK- are you sure of this? My understanding is that if you go longer than

the recommended maximum - 3 hours in the case of ala - you should stop the

round.

Do you have a reference to a quote from Andy on this? Does anyone else

remember?

---------Here's a link that posted recently, with comments from Andy

on dosing times. http://onibasu.com/archives/am/53040.html

There would be many more in archives, and I'm sure you'd find links in the

ANDY INDEX also.

My understanding has always been that if you miss your dose by more than an

hour, then you should stop the round. So if you were dosing ALA every 3 hours,

then the maximum time between doses would be 4 hours.---------Jackie

Thanks,

Dean

[Guest guest]

I have thought it was said that night time dosage could go 4 hours. We dont do

this much but on occasion I will extend one of the early am dosages to 4 hours .

In frequent-dose-chelation Jackie wrote:

In frequent-dose- chelation@ yahoogroups. com Dean wrote:

" You should not go longer than 3hr for the night

doses if you extend the lenght between doses. If you go longer than

1 hr from the last dose you are supposed to stop the round. "

TK- are you sure of this? My understanding is that if you go longer than

the recommended maximum - 3 hours in the case of ala - you should stop the

round.

Do you have a reference to a quote from Andy on this? Does anyone else

remember?

---------Here' s a link that posted recently, with comments from Andy on

dosing times. http://onibasu. com/archives/ am/53040. html

There would be many more in archives, and I'm sure you'd find links in the ANDY

INDEX also.

My understanding has always been that if you miss your dose by more than an

hour, then you should stop the round. So if you were dosing ALA every 3 hours,

then the maximum time between doses would be 4 hours.------ ---Jackie

Thanks,

Dean

[Guest guest]

In frequent-dose-chelation Largey wrote:

I have thought it was said that night time dosage could go 4 hours. We dont do

this much but on occasion I will extend one of the early am dosages to 4 hours .

-----------Yes it can. Andy has said many times that you can dose ALA every 3

hours during the day, and 4 hours at night. This will allow you to get a little

more sleep, and since metabolism is slower at night, it probably doesn't wear

off as fast, so it should be ok to go 4 hours at night.---------Jackie

In frequent-dose-chelation Jackie wrote:

In frequent-dose- chelation@ yahoogroups. com Dean wrote:

" You should not go longer than 3hr for the night

doses if you extend the lenght between doses. If you go longer than

1 hr from the last dose you are supposed to stop the round. "

TK- are you sure of this? My understanding is that if you go longer than

the recommended maximum - 3 hours in the case of ala - you should stop the

round.

Do you have a reference to a quote from Andy on this? Does anyone else

remember?

---------Here' s a link that posted recently, with comments from Andy

on dosing times. http://onibasu.com/archives/am/53040.html

There would be many more in archives, and I'm sure you'd find links in the

ANDY INDEX also.

My understanding has always been that if you miss your dose by more than an

hour, then you should stop the round. So if you were dosing ALA every 3 hours,

then the maximum time between doses would be 4 hours.------ ---Jackie

Thanks,

Dean

[Guest guest]

In frequent-dose-chelation Dean wrote:

Jackie:

Thanks for posting that. As I read Andy's comment, he clearly says it IS

okay to take a dose more than an hour later than the previous interval, so

long as it is no more than 3 hours. I presume that means 4 hours at night.

=====He says no more than 3-4 hours between doses for ALA. See quote below.

If you take a dose early (which is ok to do), then the next dose should not be

more than 3-4 hours later. 4 hours maximum between doses of ALA, and preferably

only 3.---------Jackie

Here's the quote:

" Giving doses EARLY is never a problem, unless you are not moving up

the rest of the schedule and give the subsequent one a bit late, or

gave one a lot early.

The rule is that no more than 3-4 hours (preferably 3 hours) should

elapse between any 2 doses. Less is OK. The only thing you shouldn't

do is give the 3 PM dose at 1PM then give the 6 PM dose on time - if

you give a 1 PM dose, the next dose is due at 4 PM.

Andy . . .. . . "

So in the example above, it looks like the previous dose was at noon, since

the next dose is due at 3 pm. Andy says that if you give the dose after

only an hour - at 1 pm instead of 3 pm, the next dose is due at 4 pm - 3

hours later. So he's saying it is okay to have an interval of 1 hour, then

3 hours, an increase of 2 hours.

Am I missing something here?

======He is saying that is *ok*, but it is preferable to keep the intervals

closer to 3 hours apart. This is the most important part of that quote:

" The rule is that no more than 3-4 hours (preferably 3 hours) should

elapse between any 2 doses. Less is OK. "

So technically, stretching it out to 4 hours at night is ok, but I think most

people only fluctuate their doses by one hour, not two. Personally, going from

2 hours to 4 hours is doubling the time, and sounds like too much variation to

me, but that's JMO. If this was with DMPS with a longer dosing interval to

begin with, then I would be less concerned. But with the shorter dosing times

with ALA, I would think there is a bigger difference between one and two hours.

If you are doing every 2 hours during the day, and then switch to every 4

hours at night, you have cut your total dosage in half over the night-time

hours. And then to go back to every two hours again the next day, just sounds

like alot of variation to me, and I think that's what TK was trying to warn you

about. Too much variation. And in Andy's example above, the change in dosing

times only happened once, not every night and day, so I don't think it's exactly

the same either.

I guess the bottom line is how you feel doing this, but I wouldn't recommend

this in general to everyone. I would feel better if you did 2 hours during the

day and 3 hours at night, only a one hour change, which Andy frequently

recommends with 3 hours during the day and 4 at night.

I hope this makes some sense ---------Jackie

Thanks,

Dean

In frequent-dose-chelation , Jackie wrote:

In frequent-dose-chelation Dean wrote:

" You should not go longer than 3hr for the night

doses if you extend the lenght between doses. If you go longer than

1 hr from the last dose you are supposed to stop the round. "

TK- are you sure of this? My understanding is that if you go longer than

the recommended maximum - 3 hours in the case of ala - you should stop the

round.

Do you have a reference to a quote from Andy on this? Does anyone else

remember?

---------Here's a link that posted recently, with comments from

Andy on dosing times. http://onibasu.com/archives/am/53040.html

There would be many more in archives, and I'm sure you'd find links in the

ANDY INDEX also.

My understanding has always been that if you miss your dose by more than

an hour, then you should stop the round. So if you were dosing ALA every 3

hours, then the maximum time between doses would be 4 hours.---------Jackie

Thanks,

Dean