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CF and smoking

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Hi everyone

Does anoyone have articles or info on smoking and CF. I want to give it to my

family so that they understand the effects. Having articles to print out would

be the best.

Thanks

mum to Liam wcf

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WHAT IS THERE TO SHOW THE FAMILY, YOU DONT SMOKE WHEN YOU HAVE CF IT IS A

FATAL ENOUGH LUNG DISEASE WITHOUT ADDING SMOKING TO IT. COME ON PEOPLE LETS

USE SOME COMMON SENSE. SORRY I JUST HAD TO VENT.

>

>Reply-To: cfparents

>To: <cfparents >,<crataegus >

>Subject: CF and smoking

>Date: Mon, 2 Jun 2003 08:51:18 +1200

>

>Hi everyone

>Does anoyone have articles or info on smoking and CF. I want to give it to

>my family so that they understand the effects. Having articles to print

>out would be the best.

>

>

>Thanks

>

>

> mum to Liam wcf

>

>

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sometimes people are ignorant and dont want to admit it is a bad thing to do

around CF! It is a tricky situation because they are family AND THIS SORT OF

THING CAN DESTROY FAMILES!!!

Moniquw

CF and smoking

> >Date: Mon, 2 Jun 2003 08:51:18 +1200

> >

> >Hi everyone

> >Does anoyone have articles or info on smoking and CF. I want to give it

to

> >my family so that they understand the effects. Having articles to print

> >out would be the best.

> >

> >

> >Thanks

> >

> >

> > mum to Liam wcf

> >

> >

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Some people have trouble understanding that their second hand smoke really

effects people. Also, as a former smoker, I know that most smokers don't

realize that even if they smoke outside that the carcinogens get into their

clothes and are then brought into the house. The smoky smell on clothes are

really just the carcinogens being left on the clothes. I know that many people

think that if they are not actively smoking around the child it is good enough.

They think if they air out the house and they can't smell the smoke, there is no

stuff left over in the air. But it is not true, All that junk just embedded

itself in the furniture and curtains and whatnot.

my 2 cents

CF and smoking

>Date: Mon, 2 Jun 2003 08:51:18 +1200

>

>Hi everyone

>Does anoyone have articles or info on smoking and CF. I want to give it to

>my family so that they understand the effects. Having articles to print

>out would be the best.

>

>

>Thanks

>

>

> mum to Liam wcf

>

>

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I really understand your situation. I have a sister that has smoked

for a long time and I had to tell her when Zach was born that he

could not be around any smoke. I told her, " Doctor's orders -

nobody smokes around Zach. " She was very understanding. She also

knows that we make sure we always sit in non-smoking sections at

restaurants and stay in non-smoking rooms at hotels, even if Zach is

not with us. We do not even want the smoke on our clothes.

It can be difficult for people to understand the dangers, but either

they are willing to listen or they are not. It is your

responsibility as the parent to protect your child even if it is

from a family member who is smoking. Know that you are doing the

right thing even if family members become angry with you. Best of

luck handling this difficult situation.

Sara - mommy to Zach 15 months wcf

> Hi everyone

> Does anoyone have articles or info on smoking and CF. I want to

give it to my family so that they understand the effects. Having

articles to print out would be the best.

>

>

> Thanks

>

>

> mum to Liam wcf

>

>

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Guest guest

If at all possible try to find a restaurant that is 0% SMOKING Not just smoking

and non smoking sections. this is only a disguise. It is still in the air even

if you do not smell it. i know it is had finding 100% smoke free places but IT

IS WORTH THE SEARCH!!

Re: CF and smoking

I really understand your situation. I have a sister that has smoked

for a long time and I had to tell her when Zach was born that he

could not be around any smoke. I told her, " Doctor's orders -

nobody smokes around Zach. " She was very understanding. She also

knows that we make sure we always sit in non-smoking sections at

restaurants and stay in non-smoking rooms at hotels, even if Zach is

not with us. We do not even want the smoke on our clothes.

It can be difficult for people to understand the dangers, but either

they are willing to listen or they are not. It is your

responsibility as the parent to protect your child even if it is

from a family member who is smoking. Know that you are doing the

right thing even if family members become angry with you. Best of

luck handling this difficult situation.

Sara - mommy to Zach 15 months wcf

> Hi everyone

> Does anoyone have articles or info on smoking and CF. I want to

give it to my family so that they understand the effects. Having

articles to print out would be the best.

>

>

> Thanks

>

>

> mum to Liam wcf

>

>

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I am so grateful that here in CA they have totally banned smoking in all

restaurants and most public places. Non smoking sections are a joke, the

smoke from the smoking section just drifts over to the non smoking section

anyway. I hope this ban on smoking in public goes nationwide. You can't

even smoke legally in bars here anymore, although I know of some small

places that ignore this law. I really don't care, I wouldn't take my kid to

a bar anyway.

love,

M

Re: CF and smoking

> Ever notice that whenever you go to restaurants, in order to get to the

bathroom, you have to walk through the smoking section and your CF child is

always the one who has to go? that's what happens to us.

>

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In a message dated 6/3/2003 4:10:52 AM Central Daylight Time,

brmorey@... writes:

> I am so grateful that here in CA they have totally banned smoking in all

> restaurants and most public places. Non smoking sections are a joke, the

> smoke from the smoking section just drifts over to the non smoking section

> anyway. I hope this ban on smoking in public goes nationwide. You can't

> even smoke legally in bars here anymore, although I know of some small

> places that ignore this law. I really don't care, I wouldn't take my kid to

> a bar anyway.

>

> love,

> M

>

They had those law her but are state over ruled that and they could go back

to what ever they wanted too. I loved it when I didn't have to go into a

restaurant and ask to be sited in a nonsmoking area and then they would say well

it

will be longer and I give them the look of death and say I don't care we will

wait. LOL! This just happen this month and they have been smoke free in all

the restaurants since the first of the year. It really sucks!! But it was nice

will it lasted. Deb A

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Where did you search? Try searching pubmed

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed

Type

cystic fibrosis smoke

into the search field.

I've copied a couple of the abstracts below.

~

> To elaborate, I have searched and searched and there has been no

real study on CF and smoking. > Tucker

> Mom of Milan 4 1/2 wcf

: Thorax 1999 Apr;54(4):357-66 Related Articles, Links

Health effects of passive smoking-10: Summary of effects of parental

smoking on the respiratory health of children and implications for

research.

Cook DG, Strachan DP.

Department of Public Health Sciences, St 's Hospital Medical

School, Cranmer Terrace, London SW17 0RE, UK.

BACKGROUND: Two recent reviews have assessed the effect of parental

smoking on respiratory disease in children. METHODS: The results of

the systematic quantitative review published as a series in Thorax

are summarised and brought up to date by considering papers appearing

on Embase or Medline up to June 1998. The findings are compared with

those of the review published recently by the Californian

Environmental Protection Agency (EPA). Areas requiring further

research are identified. RESULTS: Overall there is a very consistent

picture with odds ratios for respiratory illnesses and symptoms and

middle ear disease of between 1.2 and 1.6 for either parent smoking,

the odds usually being higher in pre-school than in school aged

children. For sudden infant death syndrome the odds ratio for

maternal smoking is about 2. Significant effects from paternal

smoking suggest a role for postnatal exposure to environmental

tobacco smoke. Recent publications do not lead us to alter the

conclusions of our earlier reviews. While essentially narrative

rather than systematic and quantitative, the findings of the

Californian EPA review are broadly similar. In addition they have

reviewed studies of the effects of environmental tobacco smoke on

children with cystic fibrosis and conclude from the limited evidence

that there is a strong case for a relationship between parental

smoking and admissions to hospital. They also review data from adults

of the effects of acute exposure to environmental tobacco smoke under

laboratory conditions which suggest acute effects on spirometric

parameters rather than on bronchial hyperresponsiveness. It seems

likely that such effects are also present in children. CONCLUSIONS:

Substantial benefits to children would arise if parents stopped

smoking after birth, even if the mother smoked during pregnancy.

Policies need to be developed which reduce smoking amongst parents

and protect infants and young children from exposure to environmental

tobacco smoke. The weight of evidence is such that new prevalence

studies are no longer justified. What are needed are studies which

allow comparison of the effects of critical periods of exposure to

cigarette smoke, particularly in utero, early infancy, and later

childhood. Where longitudinal studies are carried out they should be

analysed to look at the way in which changes in exposure are related

to changes in outcome. Better still would be studies demonstrating

reversibility of adverse effects, especially in asthmatic subjects or

children with cystic fibrosis.

Publication Types:

Review

Review, Tutorial

PMID: 10092699 [PubMed - indexed for MEDLINE]

*********

1: Am J Respir Crit Care Med 2002 Oct 15;166(8):1099-104 Related

Articles, Links

Pulmonary function tests in preschool children with cystic fibrosis.

Beydon N, Amsallem F, Bellet M, Boule M, Chaussain M, Denjean A,

Matran R, Pin I, Alberti C, Gaultier C.

Department of Physiology of the Debre Teaching Hospital,

Paris, France.

Pulmonary function tests have rarely been assessed in preschool

children with cystic fibrosis (CF). The objective of this multicenter

study was to compare pulmonary function in 39 preschool children with

CF (height, 90-130 cm; 16 homozygous Delta F508) and in 79 healthy

control children. Functional residual capacity (helium dilution

technique) and expiratory interrupter resistance (Rint(exp))

(interrupter technique) were measured. As compared with control

children, children with CF had significantly higher Rint(exp),

expressed as absolute values and as Z-scores (1.05 +/- 0.36 versus

0.80 +/- 0.20 kPa.L(-1). second, p < 0.0001; and 1.31 +/- 1.72 versus

0.19 +/- 0.97, p < 0.0001), and significantly lower specific

expiratory interrupter conductance (1.29 +/- 0.34 versus 1.63 +/-

0.43 kPa(-1). second, p < 0.0001). The effect of the bronchodilator

salbutamol on Rint(exp) was not significantly different between

children with CF and control children. Rint(exp) Z-scores were

significantly higher in children with CF who were exposed to passive

smoke (n = 8) (p < 0.03). Children with CF and with a history of

respiratory symptoms (n = 31) had significantly higher functional

residual capacity Z-scores (p < 0.02) and lower specific expiratory

interrupter conductance Z-scores (p < 0.04). Genotype did not

influence the data. We conclude that Rint(exp) and functional

residual capacity measurements may help to follow young children with

CF who are unable to perform reproducible forced expiratory maneuvers.

Publication Types:

Multicenter Study

PMID: 12379554 [PubMed - indexed for MEDLINE]

*************

Glycoconj J 2001 Sep;18(9):661-84 Related Articles, Links

Human airway mucin glycosylation: A combinatory of carbohydrate

determinants which vary in cystic fibrosis.

Lamblin G, Degroote S, Perini JM, Delmotte P, Scharfman A, Davril M,

Lo-Guidice JM, Houdret N, Dumur V, Klein A, Rousse P.

INSERM U 377, Faculte de Medecine and Universite de Lille 2, place de

Verdun, 59045 Lille Cedex, France.

Human airway mucins represent a very broad family of polydisperse

high molecular mass glycoproteins, which are part of the airway

innate immunity. Apomucins, which correspond to their peptide part,

are encoded by at least 6 different mucin genes (MUC1, MUC2, MUC4,

MUC5B, MUC5AC and MUC7). The expression of some of these genes (at

least MUC2 and MUC5AC) is induced by bacterial products, tobacco

smoke and different cytokines. Human airway mucins are highly

glycosylated (70-80% per weight). They contain from one single to

several hundred carbohydrate chains. The carbohydrate chains that

cover the apomucins are extremely diverse, adding to the complexity

of these molecules. Structural information is available for more than

150 different O-glycan chains corresponding to the shortest chains

(less than 12 sugars). The biosynthesis of these carbohydrate chains

is a stepwise process involving many glycosyl- or sulfo-transferases.

The only structural element shared by all mucin O-glycan chains is a

GalNAc residue linked to a serine or threonine residue of the

apomucin. There is growing evidence that the apomucin sequences

influence the first glycosylation reactions. The elongation of the

chains leads to various linear or branched extensions. Their non-

reducing end, which corresponds to the termination of the chains, may

bear different carbohydrate structures, such as histo-blood groups A

or B determinants, H and sulfated H determinants, a, b,

x or y epitopes, as well as sialyl- or sulfo- (sometimes

sialyl- and sulfo-) a or x determinants. The synthesis of

these different terminal determinants involves three different

pathways with a whole set of glycosyl- and sulfo-transferases. Due to

their wide structural diversity forming a combinatory of carbohydrate

determinants as well as their location at the surface of the airways,

mucins are involved in multiple interactions with microorganisms and

are very important in the protection of the underlying airway mucosa.

Airway mucins are oversulfated in cystic fibrosis and this feature

has been considered as being linked to a primary defect of the

disease. However, a similar pattern is observed in mucins from

patients suffering from chronic bronchitis when they are severely

infected. Airway mucins from severely infected patients suffering

either from cystic fibrosis or from chronic bronchitis are also

highly sialylated, and highly express sialylated and sulfated x

determinants, a feature which may reflect severe mucosal inflammation

or infection. These determinants are potential sites of attachment

for Pseudomonas aeruginosa, the pathogen responsible for most of the

morbidity and mortality in cystic fibrosis, and the expression of the

sulfo- and glycosyl-transferases involved in their biosynthesis is

increased by TNFalpha. In summary, airway inflammation may

simultaneously induce the expression of mucin genes (MUC2 and MUC5AC)

and the expression of several glycosyl- and sulfo-transferases,

therefore modifying the combinatory glycosylation of these molecules.

PMID: 12386453 [PubMed - in process]

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This reminds me of the email signature of a pulmonologist:

Having smoking sections is restaurants is like

having peeing sections in swimming pools.

;)

~

> I am so grateful that here in CA they have totally banned smoking

in all

> restaurants and most public places. Non smoking sections are a

joke, the

> smoke from the smoking section just drifts over to the non smoking

section

> anyway.

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This one sums it up nicely:

*************

Arch Dis Child 1994 Oct;71(4):353-4 Related Articles, Links

Passive smoking and impaired lung function in cystic fibrosis.

Smyth A, O'Hea U, G, Smyth R, Heaf D.

University of Liverpool.

Passive smoking was measured in 57 children with cystic fibrosis and

in 51 controls using a questionnaire and a measurement of urinary

cotinine concentration. In the cystic fibrosis group, cotinine was

significantly lower than in the controls. Also in this group, when

the parents smoked the child's forced expiratory volume in one second

decreased by 4% and the forced vital capacity by 3% for every 10

cigarettes smoked in the household each day.

Publication Types:

Clinical Trial

Controlled Clinical Trial

PMID: 7979533 [PubMed - indexed for MEDLINE]

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LOL thats funny!

love,

Re: CF and smoking

> This reminds me of the email signature of a pulmonologist:

>

> Having smoking sections is restaurants is like

> having peeing sections in swimming pools.

>

> ;)

> ~

>

>

> > I am so grateful that here in CA they have totally banned smoking

> in all

> > restaurants and most public places. Non smoking sections are a

> joke, the

> > smoke from the smoking section just drifts over to the non smoking

> section

> > anyway.

>

>

>

> -------------------------------------------

> The opinions and information exchanged on this list should IN NO WAY

> be construed as medical advice.

>

> PLEASE CONSULT YOUR PHYSICIAN BEFORE CHANGING ANY MEDICATIONS OR

TREATMENTS.

>

> ------------------------------------

>

>

>

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Guest guest

Your so right --THEY have done that in FLORIDA ,It is in FULL effect on July

7th . Many have been doing it since Jan 1,2003. It sure makes a difference.

Love you all

THE BEACH WAS GREAT ..I just drove in . I am addicted to you all

:):):):~~~~~~~

LOVE & HUGS, grandmomBEV

Re: CF and smoking

I am so grateful that here in CA they have totally banned smoking in all

restaurants and most public places. Non smoking sections are a joke, the

smoke from the smoking section just drifts over to the non smoking section

anyway. I hope this ban on smoking in public goes nationwide. You can't

even smoke legally in bars here anymore, although I know of some small

places that ignore this law. I really don't care, I wouldn't take my kid to

a bar anyway.

love,

M

Re: CF and smoking

> Ever notice that whenever you go to restaurants, in order to get to the

bathroom, you have to walk through the smoking section and your CF child is

always the one who has to go? that's what happens to us.

>

-------------------------------------------

The opinions and information exchanged on this list should IN NO WAY

be construed as medical advice.

PLEASE CONSULT YOUR PHYSICIAN BEFORE CHANGING ANY MEDICATIONS OR TREATMENTS.

------------------------------------

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Welcome back from us too Grandmom Queen mum :) We missed you!!

love,

M

RE: CF and smoking

> Welcome back Bev. Glad you had a good time with the family.

>

>

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Guest guest

That is so very nice of you all to post me. I sure did miss everyone. I feel

like its been a year:):):) I know all must have been well :):)

thanks again

LOVE & HUGS, GRDMBEV

Re: CF and smoking

Welcome back from us too Grandmom Queen mum :) We missed you!!

love,

M

RE: CF and smoking

> Welcome back Bev. Glad you had a good time with the family.

>

>

-------------------------------------------

The opinions and information exchanged on this list should IN NO WAY

be construed as medical advice.

PLEASE CONSULT YOUR PHYSICIAN BEFORE CHANGING ANY MEDICATIONS OR TREATMENTS.

------------------------------------

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