fracture hazard in cf patients with seizure disorder or signs

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Med. 2003 May;14(3):196-198. <A

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Bilateral fractured neck of the femur in an adult patient with cystic

fibrosis.

Lim AY, Isopescu S, Thickett KM, Gumery LB, Darby AJ, Honeybourne D,

Stableforth DE.

Adult Cystic Fibrosis Unit, Heartlands and Solihull Hospital NHS Trust,

Bordesley Green East, B9 5SS, Birmingham, UK

A 34-year-old man with cystic fibrosis (CF) sustained a bilateral fractured

neck of the femur during the course of six grand mal seizures. The fractures

were successfully treated with bipolar hemi-arthroplasties. Several risk factors

for osteoporosis were present. Bone pathology showed reduced femoral head

bone density. Osteoporosis of the lumbar spine was confirmed by dual-energy

X-ray

absorptiometry. As the life expectancy of patients with CF continues to

improve, osteoporosis and its sequelae will become more common. We should be

aware

of the increased risk of bilateral fractured neck of the femur following

epileptic seizure in CF.

PMID: 12798220 [PubMed - as supplied by publisher]

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