WEBSITE LINKS CORRECTION/ was/Oxylates, Phenol, Salicylate and Food Intolerances

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I just corrected the website links.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstra\

ct & list_uids=9092314 & query_hl=5 & itool=pubmed_docsum

factors affecting the risk for kidney stones in women

1: Ann Intern Med. 1997 Apr 1;126(7):497-504.

Comparison of dietary calcium with supplemental calcium and other

nutrients as factors affecting the risk for kidney stones in women.

Curhan GC, Willett WC, Speizer FE, Spiegelman D, Stampfer MJ.

Department of Nutrition, Harvard School of Public Health, Boston, MA

02115, USA.

BACKGROUND: Calcium intake is believed to play an important role in

the formation of kidney stones, but data on the risk factors for

stone

formation in women are limited. OBJECTIVE: To examine the

association

between intake of dietary and supplemental calcium and the risk for

kidney stones in women. DESIGN: Prospective cohort study with

12-year

follow-up. SETTING: Several U.S. states. PARTICIPANTS: 91,731 women

participating in the Nurses' Health Study I who were 34 to 59 years

of

age in 1980 and had no history of kidney stones. MEASUREMENTS:

Self-administered food-frequency questionnaires were used to assess

diet in 1980, 1984, 1986, and 1990. The main outcome measure was

incident symptomatic kidney stones. RESULTS: During 903,849

person-years of follow-up, 864 cases of kidney stones were

documented.

After adjustment for potential risk factors, intake of dietary

calcium

was inversely associated with risk for kidney stones and intake of

supplemental calcium was positively associated with risk. The

relative

risk for stone formation in women in the highest quintile of dietary

calcium intake compared with women in the lowest quintile was 0.65

(95% CI, 0.50 to 0.83). The relative risk in women who took

supplemental calcium compared with women who did not was 1.20 (CI,

1.02 to 1.41). In 67% of women who took supplemental calcium, the

calcium either was not consumed with a meal or was consumed with

meals

whose oxalate content was probably low. Other dietary factors showed

the following relative risks among women in the highest quintile of

intake compared with those in the lowest quintile: sucrose, 1.52

(CI,

1.18 to 1.96); sodium, 1.30 (CI, 1.05 to 1.62); fluid, 0.61 (CI,

0.48

to 0.78); and potassium, 0.65 (CI, 0.51 to 0.84). CONCLUSIONS: High

intake of dietary calcium appears to decrease risk for symptomatic

kidney stones, whereas intake of supplemental calcium may increase

risk. Because dietary calcium reduces the absorption of oxalate, the

apparently different effects caused by the type of calcium may be

associated with the timing of calcium ingestion relative to the

amount

of oxalate consumed. However, other factors present in dairy

products

(the major source of dietary calcium) could be responsible for the

decreased risk seen with dietary calcium.

PMID: 9092314 [PubMed - indexed for MEDLINE]

[2]

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Abstra\

ct & list_uids=9761503 & query_hl=8 & itool=pubmed_docsum

1: Nephrol Dial Transplant. 1998 Sep;13(9):2241-7

.. High-calcium intake abolishes hyperoxaluria and reduces urinary

crystallization during a 20-fold normal oxalate load in humans.

Hess B, Jost C, Zipperle L, Takkinen R, Jaeger P.

Department of Medicine, University Hospital, Berne, Switzerland.

BACKGROUND: The aim of the study was to test whether increasing

dietary calcium intake lowers intestinal oxalate absorption and

thereby prevents hyperoxaluria and urinary crystallization during a

20-fold normal oxalate load in healthy subjects. METHODS: Fourteen

healthy male volunteers (age 23-44 years, BMI 21.5-27.7 kg/m2)

collected 24-h urines while on free-choice diet as well as on two

standardized diets. The latter contained 2545 kcal, 2500 ml of

mineral

water, 102 g of protein, 13.6 g of sodium chloride and 2220 mg of

oxalate (approximately 20-fold content of an average diet). Subjects

were studied twice while on the standardized diet, once while eating

a

normal amount of calcium (1211 mg/day, oxalate-rich diet), and once

while eating 3858 mg of calcium/day (calcium and oxalate-rich diet).

RESULTS: Compared with the free-choice diet (322+/-36 micromol/d),

UOx

x V increased to 780+/-72 micromol/d on the oxalate-rich diet

(P=0.001) and fell again to 326+/-31 micromol/d on calcium and

oxalate-rich diet (P=0.001 vs oxalate-rich diet). Urinary glycolate

(a

metabolic precursor of Ox) always remained below the upper limit of

the normal range and did not change between different diets,

indicating that changes in UOX x V reflect respective variations in

intestinal absorption of Ox. Uca x V was 4.60+/-0.45 mmol/d on the

free-choice diet and 3.20+/-0.32 mmol/d on the oxalate-rich diet

(P=0.011 vs free-choice diet); it increased to 7.28+/-0.74 mmol/d on

the calcium- and oxalate-rich diet (P=0.001 vs free-choice and

oxalate-rich diets). As indicated by the AP (CaOx) index (Tiselius),

urinary supersaturation did not vary significantly between the three

diets. In freshly voided morning urines (studied in 8/14 subjects)

on

the oxalate-rich diet, CaOx crystals or crystal aggregates of up to

80

microm diameter were found in 5/8 urines, whereas this never

occurred

on the free-choice diet and only t once on the calcium- and

oxalate-rich diet. CONCLUSION: Increasing calcium intake while

eating

Ox-rich food prevents dietary hyperoxaluria and reduces CaOx

crystallization in healthy subjects. This further illustrates that

dietary counseling to idiopathic calcium-stone formers should ensure

sufficient calcium intake, especially during oxalate-rich meals.

Publication Types:

* Clinical Trial

* Randomized Controlled Trial

PMID: 9761503 [PubMed - indexed for MEDLINE]

>

> I have heard of many children who lose their phenol and salycilate

> intolerance after being on SCD for several months. However,there

are

> exceptions. It is not difficult to combine SCD with a phenol or a

> salycilate free diet.

>

> How about oxalates.? This is a very new concept so we do not have

as much data.

> However,we have a lot of hope that SCD would resolve this problem

for

> many of our ASD children. The best version for solving this

problem

> would be SCD with goat yogurt. But there is a hint that we might

even

> have success with dairy free SCD.

>

> I read about a child whose oxalate levels dropped dramatically

after

> doing SCD for 3 months. The amazing thing was that the child's

family

> was not even trying to lower the oxalate levels. Owens asked

> parents on her list for the level of oxalates in ASD children. The

> father of that child was the only one to respond to 's query.

The

> post(#6395 ) appeared on Owens' sulfurstories Yahoo list.

That

> child was doing the dairy free version of SCD. I wish we had more

> oxalate test results for children who did dairy free SCD.

>

> There is scientific proof that dairy lowers oxalate values.and the

> risk of kidney stones. The SCD yogurt is a wonderful source of

calcium

> and most of the children with autism can tolerate it after several

> months of SCD. I will write a seperate post about the goat yogurt

and

> its safety for autistic children in a few days.

>

> I am posting two articles about dairy and oxalates. The first

> research study reports that a high intake of dairy foods is more

> effective than calcium supplements to lower your risk for getting

> kidney stones. The other research paper reports that if your diet

> contains enough calcium rich foods then you do not need to worry

about

> consuming high oxalate foods.

> (However,to be safe one should avoid spinach and beets if one has

an

> oxalate problem. Nuts and beans should be used carefully because

they

> are difficult to digest. ).

>

> Mimi

>

>

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi

> ?cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=9092314

> & query_hl=13

>

> 1: Ann Intern Med. 1997 Apr 1;126(7):497-504.

>

> Comparison of dietary calcium with supplemental calcium and other

> nutrients as factors affecting the risk for kidney stones in

women.

>

> Curhan GC, Willett WC, Speizer FE, Spiegelman D, Stampfer MJ.

>

> Department of Nutrition, Harvard School of Public Health, Boston,

MA 02115, USA.

>

> BACKGROUND: Calcium intake is believed to play an important role

in

> the formation of kidney stones, but data on the risk factors for

stone

> formation in women are limited. OBJECTIVE: To examine the

association

> between intake of dietary and supplemental calcium and the risk

for

> kidney stones in women. DESIGN: Prospective cohort study with

12-year

> follow-up. SETTING: Several U.S. states. PARTICIPANTS: 91,731

women

> participating in the Nurses' Health Study I who were 34 to 59

years of

> age in 1980 and had no history of kidney stones. MEASUREMENTS:

> Self-administered food-frequency questionnaires were used to

assess

> diet in 1980, 1984, 1986, and 1990. The main outcome measure was

> incident symptomatic kidney stones. RESULTS: During 903,849

> person-years of follow-up, 864 cases of kidney stones were

documented.

> After adjustment for potential risk factors, intake of dietary

calcium

> was inversely associated with risk for kidney stones and intake of

> supplemental calcium was positively associated with risk. The

relative

> risk for stone formation in women in the highest quintile of

dietary

> calcium intake compared with women in the lowest quintile was 0.65

> (95% CI, 0.50 to 0.83). The relative risk in women who took

> supplemental calcium compared with women who did not was 1.20 (CI,

> 1.02 to 1.41). In 67% of women who took supplemental calcium, the

> calcium either was not consumed with a meal or was consumed with

meals

> whose oxalate content was probably low. Other dietary factors

showed

> the following relative risks among women in the highest quintile

of

> intake compared with those in the lowest quintile: sucrose, 1.52

(CI,

> 1.18 to 1.96); sodium, 1.30 (CI, 1.05 to 1.62); fluid, 0.61 (CI,

0.48

> to 0.78); and potassium, 0.65 (CI, 0.51 to 0.84). CONCLUSIONS:

High

> intake of dietary calcium appears to decrease risk for symptomatic

> kidney stones, whereas intake of supplemental calcium may increase

> risk. Because dietary calcium reduces the absorption of oxalate,

the

> apparently different effects caused by the type of calcium may be

> associated with the timing of calcium ingestion relative to the

amount

> of oxalate consumed. However, other factors present in dairy

products

> (the major source of dietary calcium) could be responsible for the

> decreased risk seen with dietary calcium.

>

> PMID: 9092314 [PubMed - indexed for MEDLINE]

>

> [2]

>

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi

> ?cmd=Retrieve & db=pubmed & dopt=Abstract

> & list_uids=9761503 & query_hl=13

>

> 1: Nephrol Dial Transplant. 1998 Sep;13(9):2241-7

>

> . High-calcium intake abolishes hyperoxaluria and reduces urinary

> crystallization during a 20-fold normal oxalate load in humans.

>

> Hess B, Jost C, Zipperle L, Takkinen R, Jaeger P.

>

> Department of Medicine, University Hospital, Berne, Switzerland.

>

> BACKGROUND: The aim of the study was to test whether increasing

> dietary calcium intake lowers intestinal oxalate absorption and

> thereby prevents hyperoxaluria and urinary crystallization during

a

> 20-fold normal oxalate load in healthy subjects. METHODS: Fourteen

> healthy male volunteers (age 23-44 years, BMI 21.5-27.7 kg/m2)

> collected 24-h urines while on free-choice diet as well as on two

> standardized diets. The latter contained 2545 kcal, 2500 ml of

mineral

> water, 102 g of protein, 13.6 g of sodium chloride and 2220 mg of

> oxalate (approximately 20-fold content of an average diet).

Subjects

> were studied twice while on the standardized diet, once while

eating a

> normal amount of calcium (1211 mg/day, oxalate-rich diet), and

once

> while eating 3858 mg of calcium/day (calcium and oxalate-rich

diet).

> RESULTS: Compared with the free-choice diet (322+/-36 micromol/d),

UOx

> x V increased to 780+/-72 micromol/d on the oxalate-rich diet

> (P=0.001) and fell again to 326+/-31 micromol/d on calcium and

> oxalate-rich diet (P=0.001 vs oxalate-rich diet). Urinary

glycolate (a

> metabolic precursor of Ox) always remained below the upper limit

of

> the normal range and did not change between different diets,

> indicating that changes in UOX x V reflect respective variations

in

> intestinal absorption of Ox. Uca x V was 4.60+/-0.45 mmol/d on the

> free-choice diet and 3.20+/-0.32 mmol/d on the oxalate-rich diet

> (P=0.011 vs free-choice diet); it increased to 7.28+/-0.74 mmol/d

on

> the calcium- and oxalate-rich diet (P=0.001 vs free-choice and

> oxalate-rich diets). As indicated by the AP (CaOx) index

(Tiselius),

> urinary supersaturation did not vary significantly between the

three

> diets. In freshly voided morning urines (studied in 8/14 subjects)

on

> the oxalate-rich diet, CaOx crystals or crystal aggregates of up

to 80

> microm diameter were found in 5/8 urines, whereas this never

occurred

> on the free-choice diet and only t once on the calcium- and

> oxalate-rich diet. CONCLUSION: Increasing calcium intake while

eating

> Ox-rich food prevents dietary hyperoxaluria and reduces CaOx

> crystallization in healthy subjects. This further illustrates that

> dietary counseling to idiopathic calcium-stone formers should

ensure

> sufficient calcium intake, especially during oxalate-rich meals.

>

>

>

> PMID: 9761503 [PubMed - indexed for MEDLINE]

>