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Kadian and zofran Rash -

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Hi ,

That thought about an allergic reaction has crossed my mind. So

far the closest to my face that the rash has gotten is the back of

my head. I haven't noticed any other signs of impending

anaphylaxis yet, but I know it can be quick and unexpected. I have

alerted my husband to this being a possible allergic reaction, so

we are set in what to do. But at this time, I am too hesitant to

react too rashly (no pun intended) as this is the first med that

has made me feel like a real human again. If possible, maybe I

can bargain with the doc to let me carry an epi pen in case I have

a bad reaction. In that case I will have to stop taking it I guess.

Oh, I am pretty sure it is from the kadian - most likely the time

release matrix - as I have had no rash type reaction from the IV

injections. And I have had multiple exposures to IV morphine

over the past 4 years. I check in with the doc on Monday and if it

is still there then, I will bring it to her attention. But for now, I am

keeping my fingers crossed that it will go away as my body gets

used to the meds.

Thanks for bringing this up - it is something to be concerned

about but I figure so much other things have happened that I

can't be denied the one med that makes things better - fate just

wouldn't do that to me!

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In reading your reply there are somethings about allergic

reaction that I wanted you to know. You mentioned that the rash

wasn't near your face, I don't understand, that has nothing to do

with an anaphylactic reaction, a true allergic reaction is a

histamine response, it is systemic (the entire system)

Also the amount of times a person is exposed to a substance has

nothing to do with the reaction that can occur, actually if you have

been exposed frequently it is more likely for a person to have a

reaction. A good example of this is ragweed and pollen, people have

exposures and don't even know it, but after time the body developes

a sensitivity to it and then they get itchy watery eyes (this is a

histamine reaction and why the Dr. gives them anti-histamines) the

next example would be posion ivy some people get a rash others their

whole body swells up, and some times their eyes sometimes their

airway it has nothing to do with touching the plant truely sensitive

people only have to be down wind from the plant, or near someone who

has accidently brushed against it.

I hope this helps someone prevent having a life threatening

situation.

Atwell LPN

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