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I hope this info help.....Mark

EUS (Endoscopic Ultrasound)

This is a test that combines ultrasound(sound waves) with an endoscope. The

doctor places the tube (endoscope) into the stomach and the ultrasound machine

(which is on the endoscope) is used to direct sound waves to the pancreas.

The aim of this section is to help you understand how Endoscopic

Ultrasound (EUS) can benefit you and what you can expect before, during, and

after your procedure.

Jump links to questions: Click image for larger version

Dr. Muthusamy performing an EUS procedure.

1. What is an EUS?

2. What is EUS intended to see?

3. How Do I Prepare for the Procedure?

4. What Happens When I Arrive at the Endoscopy Suite ?

5. What Can I Expect During My EUS?

6. What Type of Diagnostic Tests and Therapy Can Be Performed During My

EUS

7. What are the Possible Complications from an EUS?

8. What Can I Expect After My EUS?

9. What Symptoms Should I Look For After My Procedure That

I Need to Contact the Doctor For?

10. Summary

1. What is an EUS?

The term EUS stands for Endoscopic UltraSound.

Endoscopic refers to the use of an instrument called an endoscope - a

thin, flexible tube with a tiny video camera and light on the end. The high

quality picture from the endoscope is shown on a TV monitor; The resulting image

gives your physician a clear, detailed view of your digestive tract. The

endoscope is used by a highly trained medical specialist, a gastroenterologist,

to diagnose and treat various problems of the GI tract.

Ultrasound refers to an imaging technique that uses sound waves to produce

pictures. This principle is similar to using sonar to detect submarines.

Traditionally, this procedure has been performed by radiology doctors, who move

ultrasound probes over the skin of the abdomen to obtain images of various

organs. However, as sound waves do not travel well through air, occasionally

certain abdominal organs are not well seen due to air in the digestive tract.

Endoscopic ultrasound combines an ultrasound processor on the tip of an

endoscope, allowing for improved ultrasound imaging of the GI tract and the

abdominal organs adjacent to it. This is a result of the closer proximity of the

probe to the organs of interest as well as the ability to remove the air from

within the digestive tract via the endoscope.

The combination of the ultrasound probe and an endoscope have led to the

development of EUS scopes, or echoendoscopes. These instruments allow

examination of both the lining of your digestive tract with the endoscope, but

also of the wall of the tract and its surrounding structures such as the liver,

pancreas, bile ducts, and lymph nodes. Many other structures can also be seen.

Because of these unique capabilities, EUS can sometimes detect abnormalities or

obtain information other imaging tests cannot. EUS procedures can be done via

the mouth (Upper EUS) or via the rectum (Rectal or Lower EUS).

Echoendoscopes use ultrasound frequencies to generate images. The lower

the frequency number (say 5 megahertz), the greater the depth of penetration of

the sound waves into the abdominal tissues. However, the clarity of the image is

somewhat reduced. In contrast, the higher frequencies (typically 12 MHz) allow

for greater detail in the images, but offer more limited tissue penetration

abilities. Thus, they are not as useful for looking at structures outside the GI

tract. Most current echoendoscopes and the processors on which the images are

generated allow your doctor to choose from a range of imaging frequencies to

optimize the images obtained.

It is also possible to study the flow of blood in vessels by a process

known as Doppler ultrasound or pass a small needle down the endoscope and direct

it, under ultrasound guidance, into structures within or adjacent to your

digestive tract, such as lymph nodes or suspicious masses. In this way, tissue

can be aspirated for analysis by a pathologist. This technique is known as fine

needle aspiration aspiration (FNA).

Recently, small flexible catheters have been developed that can be passed

through a regular endoscope. They are referred to as " miniprobes " or " catheter

probes " . They provide high frequency ultrasound images (12-30 MHz), which allow

for very detailed images of the wall of the gastrointestinal tract.

Thus, EUS is a method of combining endoscopy and ultrasound imaging to

obtain high quality images of the digestive tract and its adjacent structures.

When lesions are seen, they can often be diagnosed via a fine-needle aspiration.

However, this procedure, like ERCP, requires much skill and training and is best

performed by trained experts. EUS with fine-needle aspiration also carries a

slightly increased procedure risk compared to standard endoscopy. It is

important to understand these risks and the indications for this test, as well

as possible alternatives to this procedure.

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2. What is EUS intended to see?

EUS procedures can provide a variety of information. The indications for

EUS are still undergoing development as its use is becoming more widespread. It

is primarily used to detect suspected cancers or to evaluate how far a

previously diagnosed cancer has spread in order to determine the appropriate

therapy. This latter process is called staging, and EUS is used to stage cancers

of the esophagus, stomach, pancreas, and rectum. Spread to adjacent lymph nodes

and blood vessels can be determined by the imaging and fine-needle aspiration

capabilities of EUS. EUS gives partial, but incomplete, information regarding

the spread of these tumors to adjacent organs due to its limited depth of

penetration. However, recent imaging enhancements allow for greater evaluation

of adjacent organs than previously possible.

EUS is also useful in identifying the nature of " lumps " and " bumps " seen

on a previous endoscopic exam. These bumps may represent an adjacent structure

compressing the GI tract or represent a mass or fluid collection within the wall

of the digestive tract. EUS can help differentiate between these possibilities.

EUS also plays a role in evaluating disorders of the pancreas and bile

ducts (the tubes that drain bile from your liver and gall bladder).

Visualization of the bile ducts is easily accomplished, and the pancreas can be

evaluated for the presence of masses, cysts, or changes that suggest chronic

inflammation.

More recent applications have been to evaluate patients with fecal

incontinence, stage lung cancers, and to evaluate for clots in the vessels of

the abdomen with the use of Doppler. New applications appear each year, but many

are not yet widespread.

For a more complete list of the conditions in which EUS may be helpful,

please click here (link to referral indications page for EUS).

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3. How Do I Prepare for the Procedure?

Regardless of the reason you are undergoing this procedure, there are

important steps you can take to prepare for and participate in your test. First,

if your doctor has not already reviewed them, bring any x-rays or other relevant

tests you have undergone with you. When you arrive at the endoscopy unit, be

sure to give your doctor a complete list of all the medicines you are taking and

any allergies you have to drugs or other substances. You should specifically

mention to your medical team if you are taking any aspirin containing products,

arthritis medicines such as ibuprofen, anticoagulants ( " blood thinners " ), or

diabetic medications.

The medical staff will also want to know if you have heart, lung, or other

medical conditions that may need special attention before, during, or after your

procedure. You will be given instructions in advance that will outline what you

should and should not do in preparation for your procedure. Be sure to read and

follow these instructions carefully. They are available in the procedure

preparation section of the Patient Information section of this website. Make

sure you identify the preparation specific to your doctor's office.

One very important step in preparing for your procedure is that you should

not eat or drink within six hours of your procedure. Food in the stomach will

block the view through the endoscope. In addition, you could develop pneumonia

if the food enters your lung as a result of vomiting (due to the effects of the

sedative medicines) during or after the procedure, a time your gag reflex may

not have returned to its normal state.

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4. What Happens When I Arrive at the Endoscopy Suite ?

Our EUS procedures are usually done at the endoscopy unit at Mt. Zion

Hospital. Upon arriving, you will change into a hospital gown and remove any

glasses, contacts, and dentures you may have. An intravenous needle (IV) will be

placed (typically in your arm) into which your sedative medications will be

injected when the procedure begins. A detailed medical history will be obtained

by the medical staff and you'll be asked to sign a form that verifies your

consent to proceed with the test and your understanding what is involved.

After signing the consent form, you will be taken to the specially

equipped procedure room and be connected to monitors that will measure your

heart rate, blood pressure, and the oxygenation levels of your blood throughout

the procedure. You will be asked to turn onto your left side and a plastic guard

will placed into your mouth to protect your teeth (this is only done if you are

having an Upper EUS). The sedation will then be administered through your IV.

Complete anesthesia is rarely necessary. The medications are used to provide

relief from discomfort as well as to cause " amnesia " , which usually results in

your not remembering much, if anything, about the test. At this point, the

procedure will begin.

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5. What Can I Expect During My EUS?

During the procedure, everything will be done to help you be as

comfortable as possible. Your blood pressure, pulse, and the oxygen level in

your blood will be carefully monitored. You will be relaxed and drowsy, but you

will remain awake enough to cooperate. You will not, however, be completely

anesthetized as in a surgery.

As the echoendoscope is slowly and carefully inserted, air is introduced

through it to help your doctor see better. As this is done, you should feel some

slight pressure but no pain and it should not interfere with your breathing. The

echoendocope is carefully advanced into the duodenum (for upper EUS) or the

sigmoid colon (for rectal EUS). At this time, after the endoscopic images have

been obtained, the GI tract is suctioned to remove surrounding air and the

echoendoscope is withdrawn and the appropriate structures are imaged. If an

abnormality is seen, a fine needle aspiration may be performed. Once the

appropriate images/tissue are obtained, the procedure is completed. Typically,

an EUS procedure lasts between 30 and 90 minutes.

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6. What Type of Diagnostic Tests and Therapy Can Be Performed During My

EUS?

Depending on the abnormality seen, your doctor may elect to collect some

tissue samples during the procedure. This can be done with a biopsy forceps or

via the fine needle aspiration (FNA) procedure. If a fluid collection is seen,

it can be suctioned through the scope and the fluid sent for analysis.

Occasionally, if there is a large cyst in the pancreas that needs drainage, your

doctor may place a stent through the stomach or small bowel into the pancreatic

cyst. This process is called a cyst-gastrostomy or a cyst-duodenostomy.

For patients with pancreatic cancer and severe pain, medications can be

injected into the nerves responsible for transmitting this pain. This serves to

lessen the pain in these patients for a period of up to several months. This is

called a celiac-plexus blockade. Based on current evidence, it appears to work

better for patients with pancreatic cancer than it does for patients with

chronic pancreatitis.

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7. What are the Possible Complications from an EUS?

EUS has been shown to be a safe procedure, similar to other types of

endoscopy. The risks are similar to regular endoscopy except when fine needle

aspiration is performed.

First, there is a small risk of having a reaction to the sedative

medications or antibiotics that may be given prior to your procedure. This

usually results in nausea or a skin rash and usually goes away quickly. In

addition, the medications used for sedation may cause alterations in your heart

rate or blood pressure. This is why you are monitored throughout your procedure

and during your recovery period. Medications to reverse the effects of the

sedatives are available, if necessary.

For patients undergoing EUS without FNA (also known as diagnostic EUS),

the risks of endoscopy are about 0.05%. This is about a 1 in 2000 chance of a

significant complication. The During these procedures, the major risks are

perforation (a puncture of the intestinal wall), which could require surgical

repair, and bleeding, which could require transfusion. Again, these

complications are unlikely. They typically occur from passing the scope through

a large tumor or " stretching " or dilating a tumor before or during the EUS

procedure.

For patients undergoing EUS with FNA, complications still only occur

between 0.5% - 1.0% of the time (this corresponds to a risk of 1 in 100 to 1 in

200). The risks associated with FNA include bleeding, pancreatitis (rarely, and

only if the pancreas undergoes FNA), or infection. In patients undergoing a

rectal FNA or FNA of any cystic lesion, intraprocedural antibiotics are given

and followed up with a 5 day course of oral antibiotics after the procedure.

Be aware that, occasionally, minor problems may persist, such as a mild

sore throat, bloating, or cramping. These symptoms typically disappear in 24

hours or less.

Be sure to discuss any specific concerns you may have with your doctor.

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8. What Can I Expect After My EUS?

When your EUS is completed you'll be cared for in a recovery area until

most of the effects of the medication have worn off. Typically, this takes 1-2

hours, which is longer than for standard endoscopy. This is because more

medications are needed to sedate you adequately for a longer procedure such as

EUS. You may have a mild sore throat or bloating. Patients can usually eat once

they are awake and alert. Your doctor will also inform you about the results of

the procedure and provide any additional information you need to know. EUS

procedures do not require in-hospital observation except in rare circumstances,

so you will likely be going home after the procedure. You will be given a

prescription for a 5 day course of oral antibiotics if an FNA of a cyst or

rectal lesion was performed. You will also be given guidelines for resuming your

normal activity before leaving the endoscopy unit.

By the time you're ready to go home, you should feel stronger and more

alert. Nevertheless, you should plan on resting for the remainder of the day.

This means not driving, so you'll need to have a family member or friend take

you home.

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9. What Symptoms Should I Look For After My Procedure That I Need to

Contact the Doctor For?

Occasionally, minor problems may persist, such as a mild sore throat,

bloating, or cramping; these should disappear in 24 hours or less. Should you

experience severe abdominal pain, difficulty swallowing, fever, vomiting up

blood, bloody bowel movements, or extreme dizziness/weakness, please contact

your physician regarding these symptoms. Early recognition of possible

complications is important.

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10. Summary

EUS is an advanced procedure that is performed comfortably with light to

moderate sedation. The procedure provides significant diagnostic information

upon which further treatment is usually based. In select cases, therapy can be

administered directly through the echoendoscope. Serious complications rarely

occur as a result of this procedure.

Upcoming EUS/Block

> Now that I have all my ducks in a row and have decided to go ahead

> with it. Can anyone tell me exactly what the EUS part will be like? I

> am starting to worry about that. I am a worry wart by nature and my

> track record with Medical procedures is not a good one.

>

> Any positive comments would surely help!

>

> Thanks so much ahead of time. Cyndi

>

>

>

>

>

>

>

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Thanks Jim. for the info. I have been thru enough Endoscopies and

ERCPs in the past 20 months. Don't know why it bothers me so!

I am just concerned about the combination of EUS and Nerve Block.

Will the EUS allow the Dr. to observe exactly how much damage has

occured? The Dr. keeps saying that inflammation is present but never

a clu as to how much damage has been done. I have been diabetic for

12 years. Only got the CP diagnosis 20 months ago. Anybody else you

know that had Diabetes long before CP?

Thanks, Cyndi

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