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MANUFACTURER: Manufactured

in Denmark by Pharma Nord and distributed

by

Pharma Nord (UK) Ltd

Spital Hall

Mitford

Morpeth

NE16 3PN

PRESENTATION: Tablets (150 in a

box) typically containing:

selenium (organic) 75 mg

methionine 400 mg

beta-carotene 3 mg

vitamin C 150 mg

vitamin E 47 mg

LICENSED INDICATIONS: None

CURRENT STATUS:

Pharma-Nord have given Pancreato-

Biliary Consultants an undertaking

that Bio-Antox, the formulation of which

is based entirely on the work of the

Manchester group, will not be available

" over-the-counter " . The same company

markets a range of food supplements,

one of which is called Bio-Antioxidant,

but this should not be confused with

Bio-Antox. Both contain micronutrients

and vitamins but the formulations of

each markedly differ.

DOSAGE OF Bio-Antox in PANCREATITIS

The usual dose is four tablets daily,

adjusted at intervals according to the

results of blood and urine analyses. For

most patients the initial dosage is required

for ten weeks and a few will require

supplementary methionine (250

mg four times daily). Thereafter a proportion

will continue to need a similar

dose, with or without methionine, for a

further 10 weeks with a 25 per cent

reduction in dosage for the next six

months or so. During the following six

months 50per cent of the initial dose is

given, reducing to 25 per cent as a

maintenance dose indefinitely thereafter.

Ordinarily, blood antioxidant and free

radical marker profiles are checked at

ten weeks and 20 weeks, then six

months later and then annually via the

MRI PBS.

Reference:

S Uden et al. Antioxidant therapy

for recurrent pancreatitis: placebo controlled

trial. Alimentary Pharmacology

and Therapeutics 1 - 4: 357-71

QUESTIONS TO BE ANSWERED

Q: What need is met by this therapy?

A: Treatment of patients with

chronic or recurrent acute pancreatitis

Q: What happens now?

A: Patients are treated with analgesics,

or may go on to near-total pancreatectomy

resulting in malabsorption

and diabetes.

Q: Is quality improved?

A: Yes - patients on this treatment

do not have pain.

Q: What does the treatment

cost?

A: Less than 15 pounds per

month per patient.

Q: Can cost savings be made?

A: Yes - though not quantified,

the cost of treatment with antioxidants

is likely to be much less than present

treatments.

Advice to Health Authorities and

GP's Will increase quality and effectiveness.

May result in reduced costs.

Worth considering in specification.

WARNING: Do not self

dose with these

ingredients as without

proper monitoring some

of these ingredients are

POISONOUS! Contact

MARGARET O'BRIEN in

the first instance! She is

the Chairman of the

Manchester Patient

Support Group for the

Bioantox Treatment.

TRANS FATTY ACIDS -

CONTINUED

Specific TFA Free Foods:

Krusteze brand cake and

muffin mix, Certain

Pringles Potato chips,

Smart Balance spread

(new and patented for not

containing TFA's, and for

being able to help

balance fat metabolism),

Kraft or Henry's no fat

salad dressing,

These specifics were

included because in

these food categories it's

hard to find any

products that are TFA

free. If anyone finds

more please let me know

and I'll add them to the

list. If the theory holds

and the condition of the

pancreas improves, small

amounts of other natural

fats, such as

monounsaturated,

polyunsaturated, and

saturated, may be

beneficial. Some

research indicates that a

balanced fat diet is very

important to the overall

health of an individual.

A Final Thought:: Human

evolution has been taking

place for some 4 or 5

million years. During that

long span our digestive

systems slowly adapted

to the foods that were

consumed. Now we have

been introduced to

hydrogenated oils. It is

killing or making sick

those who cannot adapt

to it. Given a few

thousands years we

won't have to worry about

hydrogenated oil

because those not able to

adapt to it will be gone.

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